Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR173C
Length:
355
Number of sequences:
5887
Description:
YDR173C ARG82 SGDID:S000002580, Chr IV from 811632-810565, Genome Release 64-1-1, reverse complement, Verified ORF, "Inositol polyphosphate multikinase (IPMK), sequentially phosphorylates Ins(1,4,5)P3 to form Ins(1,3,4,5,6)P5; also has diphosphoinositol polyphosphate synthase activity; regulates arginine-, phosphate-, and nitrogen-responsive genes"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P07250    355   IPMK_YEAST Inositol polyphosphate multikinase...3550     722     100     100GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000824; F:inositol tetrakisphosphate 3-kinase activity; IDA:SGD.::GO:0000825; F:inositol tetrakisphosphate 6-kinase activity; IDA:SGD.::GO:0000827; F:inositol-1,3,4,5,6-pentakisphosphate kinase activity; IDA:SGD.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IMP:SGD.::GO:0000823; F:inositol-1,4,5-trisphosphate 6-kinase activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035004; F:phosphatidylinositol 3-kinase activity; IDA:SGD.::GO:0030674; F:protein binding, bridging; IMP:SGD.
GO:0006525; P:arginine metabolic process; IEA:UniProtKB-KW.::GO:0032958; P:inositol phosphate biosynthetic process; IDA:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0050821; P:protein stabilization; IMP:SGD.::GO:0000821; P:regulation of arginine metabolic process; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2Q9US14    268   YK64_SCHPO Uncharacterized inositol polyphosp...2589e-25     105     30     50GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.
3Q92551    441   IP6K1_HUMAN Inositol hexakisphosphate kinase ...2553e-16     82.8     29     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0052723; F:inositol hexakisphosphate 1-kinase activity; IEA:EC.::GO:0052724; F:inositol hexakisphosphate 3-kinase activity; IEA:EC.::GO:0000832; F:inositol hexakisphosphate 5-kinase activity; IEA:EC.::GO:0004428; F:inositol or phosphatidylinositol kinase activity; IDA:UniProtKB.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.
GO:0046854; P:phosphatidylinositol phosphorylation; IDA:UniProtKB.
4Q9UHH9    426   IP6K2_HUMAN Inositol hexakisphosphate kinase ...2534e-16     82.4     28     46GO:0045111; C:intermediate filament cytoskeleton; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0052723; F:inositol hexakisphosphate 1-kinase activity; IEA:EC.::GO:0052724; F:inositol hexakisphosphate 3-kinase activity; IEA:EC.::GO:0000832; F:inositol hexakisphosphate 5-kinase activity; IEA:EC.::GO:0004428; F:inositol or phosphatidylinositol kinase activity; IDA:UniProtKB.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.
GO:0030308; P:negative regulation of cell growth; IMP:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; IDA:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.
5Q95221    425   IP6K2_RABIT Inositol hexakisphosphate kinase ...2559e-16     81.6     27     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0052723; F:inositol hexakisphosphate 1-kinase activity; IEA:EC.::GO:0052724; F:inositol hexakisphosphate 3-kinase activity; IEA:EC.::GO:0000832; F:inositol hexakisphosphate 5-kinase activity; IEA:EC.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.
6Q9R0U1    425   IP6K2_RAT Inositol hexakisphosphate kinase 2 ...2550.000000000000001     80.9     26     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0052723; F:inositol hexakisphosphate 1-kinase activity; IEA:EC.::GO:0052724; F:inositol hexakisphosphate 3-kinase activity; IEA:EC.::GO:0000832; F:inositol hexakisphosphate 5-kinase activity; IEA:EC.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.
GO:0006817; P:phosphate ion transport; IDA:RGD.
7Q9ESM0    433   IP6K1_RAT Inositol hexakisphosphate kinase 1 ...2560.000000000000002     80.9     31     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0052723; F:inositol hexakisphosphate 1-kinase activity; IEA:EC.::GO:0052724; F:inositol hexakisphosphate 3-kinase activity; IEA:EC.::GO:0000832; F:inositol hexakisphosphate 5-kinase activity; IEA:EC.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0046854; P:phosphatidylinositol phosphorylation; ISS:UniProtKB.
8Q80V72    448   IP6K2_MOUSE Inositol hexakisphosphate kinase ...2550.000000000000002     80.9     26     43GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0052723; F:inositol hexakisphosphate 1-kinase activity; IEA:EC.::GO:0052724; F:inositol hexakisphosphate 3-kinase activity; IEA:EC.::GO:0000832; F:inositol hexakisphosphate 5-kinase activity; IEA:EC.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.
9Q6PD10    433   IP6K1_MOUSE Inositol hexakisphosphate kinase ...2560.000000000000008     79     30     46GO:0005737; C:cytoplasm; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0052723; F:inositol hexakisphosphate 1-kinase activity; IEA:EC.::GO:0052724; F:inositol hexakisphosphate 3-kinase activity; IEA:EC.::GO:0000832; F:inositol hexakisphosphate 5-kinase activity; IEA:EC.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.
GO:0046854; P:phosphatidylinositol phosphorylation; ISS:UniProtKB.
10Q96PC2    410   IP6K3_HUMAN Inositol hexakisphosphate kinase ...2550.00000000000002     77.4     27     42GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0052723; F:inositol hexakisphosphate 1-kinase activity; IEA:EC.::GO:0052724; F:inositol hexakisphosphate 3-kinase activity; IEA:EC.::GO:0000832; F:inositol hexakisphosphate 5-kinase activity; IEA:EC.::GO:0000831; F:inositol hexakisphosphate 6-kinase activity; IDA:MGI.::GO:0004428; F:inositol or phosphatidylinositol kinase activity; IDA:UniProtKB.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.
GO:0032958; P:inositol phosphate biosynthetic process; IDA:MGI.::GO:0046488; P:phosphatidylinositol metabolic process; IDA:UniProtKB.::GO:0006468; P:protein phosphorylation; IDA:UniProtKB.
11Q8NFU5    416   IPMK_HUMAN Inositol polyphosphate multikinase...2750.00000000000003     77     28     45GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000823; F:inositol-1,4,5-trisphosphate 6-kinase activity; IEA:EC.
12Q99NI4    396   IPMK_RAT Inositol polyphosphate multikinase O...2690.0000000000002     74.3     28     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000823; F:inositol-1,4,5-trisphosphate 6-kinase activity; IEA:EC.
13Q8BWD2    396   IP6K3_MOUSE Inositol hexakisphosphate kinase ...2530.0000000000003     73.9     26     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0052723; F:inositol hexakisphosphate 1-kinase activity; IEA:EC.::GO:0052724; F:inositol hexakisphosphate 3-kinase activity; IEA:EC.::GO:0000832; F:inositol hexakisphosphate 5-kinase activity; IEA:EC.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.
14Q7TT16    396   IPMK_MOUSE Inositol polyphosphate multikinase...2680.0000000000007     72.8     28     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000824; F:inositol tetrakisphosphate 3-kinase activity; IMP:MGI.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IMP:MGI.::GO:0000823; F:inositol-1,4,5-trisphosphate 6-kinase activity; IEA:EC.
GO:0032958; P:inositol phosphate biosynthetic process; IMP:MGI.::GO:0001841; P:neural tube formation; IMP:MGI.
15O74561    967   YCZ8_SCHPO Uncharacterized inositol polyphosp...1680.000000002     62.8     29     46GO:0005829; C:cytosol; IDA:PomBase.
GO:0000829; F:inositol heptakisphosphate kinase activity; ISS:PomBase.::GO:0000827; F:inositol-1,3,4,5,6-pentakisphosphate kinase activity; ISS:PomBase.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.
GO:0032958; P:inositol phosphate biosynthetic process; ISS:PomBase.::GO:0048016; P:inositol phosphate-mediated signaling; NAS:PomBase.::GO:0006797; P:polyphosphate metabolic process; NAS:PomBase.
16Q9LY23    286   IPMKA_ARATH Inositol polyphosphate multikinas...1710.00005     47.8     26     42GO:0005829; C:cytosol; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047326; F:inositol tetrakisphosphate 5-kinase activity; IEA:EC.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.::GO:0000823; F:inositol-1,4,5-trisphosphate 6-kinase activity; IDA:TAIR.
GO:0009846; P:pollen germination; IMP:TAIR.::GO:0009860; P:pollen tube growth; IMP:TAIR.
17Q12494    1050   KCS1_YEAST Inositol hexakisphosphate kinase 1...1590.0001     47.8     25     47GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0033200; F:inositol heptakisphosphate 5-kinase activity; ISS:SGD.::GO:0052723; F:inositol hexakisphosphate 1-kinase activity; IEA:EC.::GO:0052724; F:inositol hexakisphosphate 3-kinase activity; IEA:EC.::GO:0000832; F:inositol hexakisphosphate 5-kinase activity; IEA:EC.::GO:0000827; F:inositol-1,3,4,5,6-pentakisphosphate kinase activity; IDA:SGD.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.
GO:0032958; P:inositol phosphate biosynthetic process; IDA:SGD.
18Q9FLT2    300   IPMKB_ARATH Inositol polyphosphate multikinas...1800.0001     47     25     42GO:0005634; C:nucleus; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0047326; F:inositol tetrakisphosphate 5-kinase activity; IEA:EC.::GO:0052725; F:inositol-1,3,4-trisphosphate 6-kinase activity; IDA:TAIR.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:InterPro.::GO:0000823; F:inositol-1,4,5-trisphosphate 6-kinase activity; IDA:TAIR.
GO:0010264; P:myo-inositol hexakisphosphate biosynthetic process; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.
19O14007    474   CBF5_SCHPO H/ACA ribonucleoprotein complex su...891.8     34.3     28     48GO:0031429; C:box H/ACA snoRNP complex; ISS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0034513; F:box H/ACA snoRNA binding; IC:PomBase.::GO:0009982; F:pseudouridine synthase activity; ISS:PomBase.
GO:0000495; P:box H/ACA snoRNA 3'-end processing; ISS:PomBase.::GO:0031118; P:rRNA pseudouridine synthesis; ISS:PomBase.::GO:0031120; P:snRNA pseudouridine synthesis; ISS:PomBase.::GO:0006399; P:tRNA metabolic process; NAS:PomBase.
20P23677    461   IP3KA_HUMAN Inositol-trisphosphate 3-kinase A...393.1     33.5     44     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; TAS:ProtInc.
GO:0007165; P:signal transduction; TAS:ProtInc.
21P17105    459   IP3KA_RAT Inositol-trisphosphate 3-kinase A O...393.2     33.5     44     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IDA:RGD.
22Q8R071    459   IP3KA_MOUSE Inositol-trisphosphate 3-kinase A...393.3     33.5     44     59
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0008440; F:inositol-1,4,5-trisphosphate 3-kinase activity; IEA:EC.
GO:0006020; P:inositol metabolic process; IMP:MGI.
23Q03746    1174   CR1FA_BACTA Pesticidal crystal protein cry1Fa...2096.3     32.7     22     40
GO:0005102; F:receptor binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:InterPro.::GO:0009405; P:pathogenesis; IEA:InterPro.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
24O17919    445   DKC1_CAEEL Putative H/ACA ribonucleoprotein c...897.9     32     29     45GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
GO:0009982; F:pseudouridine synthase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0001522; P:pseudouridine synthesis; IEA:InterPro.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
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