Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR172W
Length:
685
Number of sequences:
5887
Description:
YDR172W SUP35 SGDID:S000002579, Chr IV from 808324-810381, Genome Release 64-1-1, Verified ORF, "Translation termination factor eRF3, has a role in mRNA deadenylation and decay; altered protein conformation creates the [PSI(+)] prion that alters translational fidelity and results in a nonsense suppressor phenotype"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P05453    685   ERF3_YEAST Eukaryotic peptide chain release f...6850     1419     100     100GO:0005829; C:cytosol; TAS:Reactome.::GO:0018444; C:translation release factor complex; IDA:SGD.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003747; F:translation release factor activity; IDA:SGD.
GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IPI:SGD.
2Q9HGI4    662   ERF3_ZYGRO Eukaryotic peptide chain release f...5660     913     79     89GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003747; F:translation release factor activity; IEA:InterPro.
3Q9HGI8    700   ERF3_KLULA Eukaryotic peptide chain release f...6840     900     69     77GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003747; F:translation release factor activity; IEA:InterPro.
4Q9HGI7    712   ERF3_CANMA Eukaryotic peptide chain release f...6550     854     69     79GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003747; F:translation release factor activity; IEA:InterPro.
5Q9HGI6    701   ERF3_DEBHA Eukaryotic peptide chain release f...6420     837     67     77GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003747; F:translation release factor activity; IEA:InterPro.
6O13354    715   ERF3_CANAX Eukaryotic peptide chain release f...6430     832     66     77GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003747; F:translation release factor activity; IEA:InterPro.
7P23637    741   ERF3_OGAPI Eukaryotic peptide chain release f...5830     797     66     80GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003747; F:translation release factor activity; IEA:InterPro.
8O74718    662   ERF3_SCHPO Eukaryotic peptide chain release f...6230     651     52     70GO:0005829; C:cytosol; IDA:PomBase.::GO:0018444; C:translation release factor complex; IPI:PomBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0046982; F:protein heterodimerization activity; IPI:PomBase.::GO:0003747; F:translation release factor activity; IGI:PomBase.
GO:0002184; P:cytoplasmic translational termination; NAS:PomBase.
9P15170    499   ERF3A_HUMAN Eukaryotic peptide chain release ...4271e-180     530     57     75GO:0005622; C:intracellular; NAS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003747; F:translation release factor activity; IMP:UniProtKB.
GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:UniProtKB.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:UniProtKB.::GO:0006479; P:protein methylation; IDA:MGI.
10Q8IYD1    628   ERF3B_HUMAN Eukaryotic peptide chain release ...4274e-179     531     57     75GO:0005829; C:cytosol; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; TAS:Reactome.::GO:0006415; P:translational termination; TAS:Reactome.
11Q5R4B3    628   ERF3B_PONAB Eukaryotic peptide chain release ...4276e-179     531     57     75GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006412; P:translation; IEA:UniProtKB-KW.
12Q149F3    632   ERF3B_MOUSE Eukaryotic peptide chain release ...4277e-179     531     56     76GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.::GO:0006412; P:translation; IEA:UniProtKB-KW.
13Q8R050    636   ERF3A_MOUSE Eukaryotic peptide chain release ...4274e-178     529     57     75
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003747; F:translation release factor activity; ISS:UniProtKB.
GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
14Q7YZN9    557   ERF3_DICDI Eukaryotic peptide chain release f...4312e-125     390     45     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
15Q9Y450    684   HBS1L_HUMAN HBS1-like protein OS=Homo sapiens...4331e-110     355     42     61
GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; TAS:ProtInc.
16Q5R6Y0    684   HBS1L_PONAB HBS1-like protein OS=Pongo abelii...4332e-110     355     42     61
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
17A1RXW9    433   EF1A_THEPD Elongation factor 1-alpha OS=Therm...4283e-109     344     41     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
18A3DMQ1    438   EF1A_STAMF Elongation factor 1-alpha OS=Staph...4337e-106     335     40     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
19Q2KHZ2    686   HBS1L_BOVIN HBS1-like protein OS=Bos taurus (...4331e-105     343     43     61
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
20Q6AXM7    679   HBS1L_RAT HBS1-like protein OS=Rattus norvegi...4331e-105     342     42     61
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
21Q69ZS7    682   HBS1L_MOUSE HBS1-like protein OS=Mus musculus...4332e-105     342     42     61
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
22Q04634    435   EF1A_TETPY Elongation factor 1-alpha OS=Tetra...4316e-104     330     40     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
23P41203    438   EF1A_DESMO Elongation factor 1-alpha OS=Desul...4287e-103     328     39     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
24P86933    449   EF1A_TRYBB Elongation factor 1-alpha OS=Trypa...4267e-103     328     40     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
25P86939    449   EF1A2_TRYB2 Elongation factor 1-alpha 2 OS=Tr...4262e-102     327     40     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
26P86934    449   EF1A1_TRYB2 Elongation factor 1-alpha 1 OS=Tr...4262e-102     327     40     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
27P18624    453   EF1A_DICDI Elongation factor 1-alpha OS=Dicty...4295e-102     326     41     60GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0030175; C:filopodium; IDA:dictyBase.::GO:0030027; C:lamellipodium; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0051015; F:actin filament binding; IDA:dictyBase.::GO:0005525; F:GTP binding; TAS:dictyBase.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IDA:dictyBase.
GO:0051017; P:actin filament bundle assembly; IDA:dictyBase.::GO:0009617; P:response to bacterium; IEP:dictyBase.
28A8MAJ1    444   EF1A_CALMQ Elongation factor 1-alpha OS=/ IC-...4291e-101     325     41     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
29A8ABM5    442   EF1A_IGNH4 Elongation factor 1-alpha OS=Ignic...4302e-101     323     38     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
30P50256    449   EF1AC_PORPU Elongation factor 1-alpha C OS=Po...4311e-100     322     40     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
31P54959    434   EF1A_BLAHO Elongation factor 1-alpha OS=Blast...4265e-100     320     39     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0003746; F:translation elongation factor activity; IEA:UniProtKB-KW.
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