Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR170C
Length:
2009
Number of sequences:
5887
Description:
YDR170C SEC7 SGDID:S000002577, Chr IV from 802222-796193, Genome Release 64-1-1, reverse complement, Verified ORF, "Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P11075    2009   SEC7_YEAST Protein transport protein SEC7 OS=...20090     4136     100     100GO:0005829; C:cytosol; IDA:SGD.::GO:0005798; C:Golgi-associated vesicle; IDA:SGD.::GO:0005770; C:late endosome; IDA:SGD.::GO:0005802; C:trans-Golgi network; IDA:SGD.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:SGD.::GO:0005488; F:binding; IEA:InterPro.
GO:0000045; P:autophagic vacuole assembly; IMP:SGD.::GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
2Q9UT02    1811   SEC7A_SCHPO Protein transport protein sec71 O...18670     957     33     54GO:0005798; C:Golgi-associated vesicle; ISS:PomBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; ISS:PomBase.::GO:0005488; F:binding; IEA:InterPro.
GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; ISS:PomBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
3Q9P7V5    1822   SEC7B_SCHPO Protein transport protein sec72 O...1962e-21     106     31     55GO:0005938; C:cell cortex; IDA:PomBase.::GO:0000137; C:Golgi cis cisterna; IDA:PomBase.::GO:0000138; C:Golgi trans cisterna; IDA:PomBase.::GO:0005798; C:Golgi-associated vesicle; ISS:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; ISS:PomBase.::GO:0005488; F:binding; IEA:InterPro.
GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; ISS:PomBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
4Q9Y6D5    1785   BIG2_HUMAN Brefeldin A-inhibited guanine nucl...2113e-20     102     31     55GO:0005829; C:cytosol; IDA:MGI.::GO:0000139; C:Golgi membrane; IDA:MGI.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
GO:0006887; P:exocytosis; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IDA:MGI.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
5O46382    1849   BIG1_BOVIN Brefeldin A-inhibited guanine nucl...2853e-22     109     28     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005488; F:binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
6Q9Y6D6    1849   BIG1_HUMAN Brefeldin A-inhibited guanine nucl...1610.0000000003     69.7     28     55GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0017022; F:myosin binding; IPI:UniProtKB.
GO:0006887; P:exocytosis; TAS:ProtInc.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
7Q42510    1451   EMB30_ARATH Pattern formation protein EMB30 O...3607.8     35.4     18     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0010292; F:GTP:GDP antiporter activity; IGI:TAIR.::GO:0042803; F:protein homodimerization activity; IPI:TAIR.
GO:0010540; P:basipetal auxin transport; IMP:TAIR.::GO:0007155; P:cell adhesion; IMP:TAIR.::GO:0007047; P:cellular cell wall organization; IMP:TAIR.::GO:0000911; P:cytokinesis by cell plate formation; IMP:TAIR.::GO:0010386; P:lateral root primordium development; IMP:TAIR.::GO:0009942; P:longitudinal axis specification; IMP:TAIR.::GO:0010087; P:phloem or xylem histogenesis; IMP:TAIR.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0048209; P:regulation of vesicle targeting, to, from or within Golgi; TAS:TAIR.::GO:0009826; P:unidimensional cell growth; IMP:TAIR.
8Q54KA7    986   SECG_DICDI Ankyrin repeat, PH and SEC7 domain...2062e-48     193     46     64GO:0005829; C:cytosol; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0031589; P:cell-substrate adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
9P63034    400   CYH2_MOUSE Cytohesin-2 OS=Mus musculus (Mouse...1862e-47     181     48     67GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
10P63035    400   CYH2_RAT Cytohesin-2 OS=Rattus norvegicus (Ra...1863e-47     181     48     67GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.
GO:0016358; P:dendrite development; TAS:RGD.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
11Q76MY7    399   CYH2_CHLAE Cytohesin-2 OS=Chlorocebus aethiop...1863e-47     181     48     67GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
12Q99418    400   CYH2_HUMAN Cytohesin-2 OS=Homo sapiens (Human...1863e-47     181     48     67GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0006897; P:endocytosis; TAS:ProtInc.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
13Q2KI41    410   CYH2_BOVIN Cytohesin-2 OS=Bos taurus (Bovine)...1864e-47     181     48     67GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; ISS:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; ISS:RefGenome.
14P97694    398   CYH1_RAT Cytohesin-1 OS=Rattus norvegicus (Ra...1754e-46     178     49     68GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
15Q9QX11    398   CYH1_MOUSE Cytohesin-1 OS=Mus musculus (Mouse...1754e-46     178     49     68GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005923; C:tight junction; IDA:MGI.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0090162; P:establishment of epithelial cell polarity; IMP:MGI.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
16Q15438    398   CYH1_HUMAN Cytohesin-1 OS=Homo sapiens (Human...1752e-45     176     49     67GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IDA:MGI.::GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
17Q76MZ1    398   CYH1_CHLAE Cytohesin-1 OS=Chlorocebus aethiop...1752e-45     176     49     67GO:0005622; C:intracellular; IEA:InterPro.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
18O08967    399   CYH3_MOUSE Cytohesin-3 OS=Mus musculus (Mouse...1754e-44     172     48     65GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IPI:MGI.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.
GO:0090162; P:establishment of epithelial cell polarity; IMP:MGI.::GO:0045785; P:positive regulation of cell adhesion; IDA:MGI.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
19P97696    400   CYH3_RAT Cytohesin-3 OS=Rattus norvegicus (Ra...1754e-44     172     48     65GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
20O43739    400   CYH3_HUMAN Cytohesin-3 OS=Homo sapiens (Human...1752e-43     170     47     65GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005545; F:1-phosphatidylinositol binding; TAS:ProtInc.::GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; TAS:ProtInc.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.::GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
21Q9UIA0    394   CYH4_HUMAN Cytohesin-4 OS=Homo sapiens (Human...1687e-42     165     49     64GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
22Q92538    1859   GBF1_HUMAN Golgi-specific brefeldin A-resista...7972e-41     172     23     42GO:0000139; C:Golgi membrane; TAS:Reactome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0048205; P:COPI coating of Golgi vesicle; TAS:Reactome.::GO:0006892; P:post-Golgi vesicle-mediated transport; TAS:Reactome.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:Reactome.
23Q80YW0    393   CYH4_MOUSE Cytohesin-4 OS=Mus musculus (Mouse...1684e-40     160     48     64GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
24Q9R1D7    1856   GBF1_CRIGR Golgi-specific brefeldin A-resista...7995e-40     167     24     42GO:0005622; C:intracellular; IEA:InterPro.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
25Q6DN90    963   IQEC1_HUMAN IQ motif and SEC7 domain-containi...2015e-36     153     37     62GO:0030054; C:cell junction; IDA:HPA.::GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
26Q8R0S2    961   IQEC1_MOUSE IQ motif and SEC7 domain-containi...2016e-36     152     37     62GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
27Q5JU85    1478   IQEC2_HUMAN IQ motif and SEC7 domain-containi...1819e-35     150     39     64GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
28Q5DU25    1478   IQEC2_MOUSE IQ motif and SEC7 domain-containi...1819e-35     150     39     64GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
29Q9P7R8    1462   YHV3_SCHPO Uncharacterized protein C211.03 OS...4021e-34     149     28     46GO:0005829; C:cytosol; IDA:PomBase.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; ISS:PomBase.::GO:0005488; F:binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; ISS:PomBase.::GO:0006888; P:ER to Golgi vesicle-mediated transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
30Q76M68    1194   IQEC3_RAT IQ motif and SEC7 domain-containing...2201e-33     145     35     56GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032857; P:activation of ARF GTPase activity; IDA:UniProtKB.
31Q3TES0    1195   IQEC3_MOUSE IQ motif and SEC7 domain-containi...2202e-33     145     35     56GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0060077; C:inhibitory synapse; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; IDA:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
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