UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR170C

Length:

2009

Number of sequences:

5887

Description:

YDR170C SEC7 SGDID:S000002577, Chr IV from 802222-796193, Genome Release 64-1-1, reverse complement, Verified ORF, "Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	Q80TL7	1715	MON2_MOUSE Protein MON2 homolog OS=Mus muscul...	245	0.67	38.9	23	41	GO:0005737; C:cytoplasm; IBA:RefGenome.
									GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005488; F:binding; IEA:InterPro.
									GO:0006895; P:Golgi to endosome transport; ISS:HGNC.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
62	Q7Z3U7	1718	MON2_HUMAN Protein MON2 homolog OS=Homo sapie...	460	0.004	46.2	20	37	GO:0005737; C:cytoplasm; IBA:RefGenome.
									GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005488; F:binding; IEA:InterPro.
									GO:0006895; P:Golgi to endosome transport; ISS:HGNC.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
63	C5DQU9	833	YEL1_ZYGRC Guanine-nucleotide exchange factor...	102	0.004	45.8	28	52	GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
									GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
64	Q61SD1	1645	MON2_CAEBR Protein MON2 homolog OS=Caenorhabd...	422	0.006	45.4	18	38
									GO:0005488; F:binding; IEA:InterPro.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.
65	Q9XYH7	349	MIC6_TOXGO Micronemal protein 6 OS=Toxoplasma...	75	0.011	43.9	37	53	GO:0031410; C:cytoplasmic vesicle; IEA:UniProtKB-KW.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0033163; C:microneme membrane; IEA:UniProtKB-SubCell.
									GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
66	P0C6U5	4421	R1A_CVHN5 Replicase polyprotein 1a OS=Human c...	116	0.38	39.7	25	47	GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
									GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
67	Q6UDG4	433	UL01_PSHV1 Uncharacterized protein UL-1 OS=(P...	126	2.6	36.6	27	42	GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
68	Q6GP04	1721	MON2_XENLA Protein MON2 homolog OS=Xenopus la...	286	0.14	41.2	23	41
									GO:0005488; F:binding; IEA:InterPro.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.
69	P0C6X4	7132	R1AB_CVHN5 Replicase polyprotein 1ab OS=Human...	116	0.66	38.9	25	47	GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
70	P0C6U4	4441	R1A_CVHN2 Replicase polyprotein 1a OS=Human c...	97	0.43	39.7	32	53	GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
									GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
71	P0C6X3	7152	R1AB_CVHN2 Replicase polyprotein 1ab OS=Human...	135	0.56	39.3	27	47	GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
72	A8MU46	457	SMTL1_HUMAN Smoothelin-like protein 1 OS=Homo...	184	0.48	38.9	22	41	GO:0031674; C:I band; IEA:UniProtKB-SubCell.::GO:0031430; C:M band; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
									GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
									GO:0045908; P:negative regulation of vasodilation; ISS:UniProtKB.::GO:0045907; P:positive regulation of vasoconstriction; ISS:UniProtKB.
73	P0C6U3	4471	R1A_CVHN1 Replicase polyprotein 1a OS=Human c...	97	0.81	38.5	32	52	GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
									GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
74	P0C6X2	7182	R1AB_CVHN1 Replicase polyprotein 1ab OS=Human...	97	0.89	38.5	32	52	GO:0044172; C:host cell endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.::GO:0033644; C:host cell membrane; IEA:UniProtKB-SubCell.::GO:0044220; C:host cell perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:InterPro.::GO:0019034; C:viral replication complex; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0016896; F:exoribonuclease activity, producing 5'-phosphomonoesters; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008168; F:methyltransferase activity; IEA:InterPro.::GO:0008242; F:omega peptidase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0003968; F:RNA-directed RNA polymerase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.::GO:0019079; P:viral genome replication; IEA:InterPro.::GO:0019082; P:viral protein processing; IEA:InterPro.
75	C7GNA4	687	YEL1_YEAS2 Guanine-nucleotide exchange factor...	139	0.13	40.8	24	46	GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
									GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
76	B3LNJ6	687	YEL1_YEAS1 Guanine-nucleotide exchange factor...	139	0.13	40.8	24	46	GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
									GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
77	P12027	542	PSGP_ONCMY Polysialoglycoprotein OS=Oncorhync...	203	0.33	39.7	23	41
78	Q12019	4910	MDN1_YEAST Midasin OS=Saccharomyces cerevisia...	136	4.1	36.2	31	46	GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005654; C:nucleoplasm; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IEA:InterPro.::GO:0008134; F:transcription factor binding; IEA:InterPro.
									GO:0006461; P:protein complex assembly; IEA:InterPro.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0000027; P:ribosomal large subunit assembly; IMP:SGD.::GO:0006364; P:rRNA processing; IMP:SGD.
79	P0C7Q8	532	DA1_ARATH Protein DA1 OS=Arabidopsis thaliana...	71	0.23	40	31	52
									GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0046621; P:negative regulation of organ growth; IMP:TAIR.::GO:0048482; P:ovule morphogenesis; IMP:TAIR.::GO:0048317; P:seed morphogenesis; IMP:TAIR.
80	P06836	242	NEUM_BOVIN Neuromodulin OS=Bos taurus (Bovine...	166	0.24	39.3	22	39	GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0031527; C:filopodium membrane; IEA:UniProtKB-SubCell.::GO:0032584; C:growth cone membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
									GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
									GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
81	P53353	349	ASPX_VULVU Sperm acrosomal protein FSA-ACR.1 ...	207	2.7	36.2	22	43	GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.
82	P29362	404	LMP1_EBVC Latent membrane protein 1 OS=Epstei...	132	0.34	39.3	23	40	GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0019087; P:transformation of host cell by virus; IEA:InterPro.
83	O54935	633	XRCC1_CRIGR DNA repair protein XRCC1 OS=Crice...	119	0.36	39.3	24	45	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0003684; F:damaged DNA binding; IEA:InterPro.
									GO:0000012; P:single strand break repair; IEA:InterPro.
84	P34225	687	YEL1_YEAST Guanine-nucleotide exchange factor...	139	0.42	39.3	24	45	GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:SGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.
									GO:0051666; P:actin cortical patch localization; IMP:SGD.::GO:0010513; P:positive regulation of phosphatidylinositol biosynthetic process; IMP:SGD.::GO:0008104; P:protein localization; IMP:SGD.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
85	C8Z3N7	687	YEL1_YEAS8 Guanine-nucleotide exchange factor...	139	0.42	39.3	24	45	GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
									GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
86	A6ZKN8	687	YEL1_YEAS7 Guanine-nucleotide exchange factor...	139	0.42	39.3	24	45	GO:0005935; C:cellular bud neck; IEA:UniProtKB-SubCell.::GO:0005934; C:cellular bud tip; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
									GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
87	Q9NU22	5596	MDN1_HUMAN Midasin OS=Homo sapiens (Human). G...	135	0.52	39.3	28	45	GO:0005634; C:nucleus; NAS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; NAS:UniProtKB.::GO:0051082; F:unfolded protein binding; NAS:UniProtKB.
									GO:0006461; P:protein complex assembly; NAS:UniProtKB.
88	O77374	1119	PF07_PLAF7 Uncharacterized protein PFC0810c O...	136	0.54	38.9	27	46
89	Q969E4	200	TCAL3_HUMAN Transcription elongation factor A...	114	3.2	35.4	25	41	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
90	Q9N2G5	637	CLIC6_RABIT Chloride intracellular channel pr...	134	1	38.1	23	41	GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
91	O55176	578	PJA1_MOUSE E3 ubiquitin-protein ligase Praja-...	225	1.1	37.7	23	41	GO:0005737; C:cytoplasm; IDA:MGI.
									GO:0005515; F:protein binding; IPI:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0030163; P:protein catabolic process; IDA:MGI.

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