Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR170C
Length:
2009
Number of sequences:
5887
Description:
YDR170C SEC7 SGDID:S000002577, Chr IV from 802222-796193, Genome Release 64-1-1, reverse complement, Verified ORF, "Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q3TES0    1195   IQEC3_MOUSE IQ motif and SEC7 domain-containi...2202e-33     145     35     56GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0060077; C:inhibitory synapse; IDA:UniProtKB.::GO:0045211; C:postsynaptic membrane; IDA:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
32Q9UPP2    1182   IQEC3_HUMAN IQ motif and SEC7 domain-containi...2202e-33     145     35     56GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
33P39993    1459   GEA2_YEAST ARF guanine-nucleotide exchange fa...2076e-31     137     36     57GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0019898; C:extrinsic to membrane; IDA:SGD.::GO:0000137; C:Golgi cis cisterna; IDA:SGD.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:SGD.
GO:0030036; P:actin cytoskeleton organization; IGI:SGD.::GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IMP:SGD.::GO:0016236; P:macroautophagy; IMP:SGD.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IGI:SGD.::GO:0033363; P:secretory granule organization; IMP:SGD.
34P47102    1408   GEA1_YEAST ARF guanine-nucleotide exchange fa...2171e-29     133     36     53GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0019898; C:extrinsic to membrane; IDA:SGD.::GO:0000137; C:Golgi cis cisterna; IDA:SGD.::GO:0005798; C:Golgi-associated vesicle; IPI:SGD.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:SGD.
GO:0030036; P:actin cytoskeleton organization; IGI:SGD.::GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IMP:SGD.::GO:0016236; P:macroautophagy; IMP:SGD.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IGI:SGD.
35P34512    393   GRP1_CAEEL GTP exchange factor for ARFs 1 OS=...1504e-26     117     41     61GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
36Q8NDX1    1056   PSD4_HUMAN PH and SEC7 domain-containing prot...1491e-22     110     36     59GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
37Q8BLR5    1005   PSD4_MOUSE PH and SEC7 domain-containing prot...1552e-22     108     34     59GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
38Q5DTT2    1024   PSD1_MOUSE PH and SEC7 domain-containing prot...1493e-22     108     36     60GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
39A5PKW4    1024   PSD1_HUMAN PH and SEC7 domain-containing prot...1493e-22     108     36     60GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; NAS:UniProtKB.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
40Q9ESQ7    649   PSD1_RAT PH and SEC7 domain-containing protei...1496e-22     106     36     60GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0016021; C:integral to membrane; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0001409; F:guanine nucleotide transmembrane transporter activity; TAS:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0015854; P:guanine transport; TAS:RGD.::GO:0030182; P:neuron differentiation; IEP:RGD.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
41Q2PFD7    1037   PSD3_MOUSE PH and SEC7 domain-containing prot...1505e-21     104     33     60GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032011; P:ARF protein signal transduction; IC:MGI.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
42Q9BQI7    771   PSD2_HUMAN PH and SEC7 domain-containing prot...1491e-20     102     34     60GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
43Q6P1I6    770   PSD2_MOUSE PH and SEC7 domain-containing prot...1491e-20     102     34     60GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0030425; C:dendrite; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0043025; C:neuronal cell body; IDA:MGI.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
44F1MUS9    1026   PSD1_BOVIN PH and SEC7 domain-containing prot...1492e-20     103     35     57GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
45Q9NYI0    1048   PSD3_HUMAN PH and SEC7 domain-containing prot...1502e-20     102     33     60GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
46Q9QZN3    319   FBX8_MOUSE F-box only protein 8 OS=Mus muscul...1993e-18     92.4     33     51GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0000151; C:ubiquitin ligase complex; IPI:MGI.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IPI:MGI.
47Q9NRD0    319   FBX8_HUMAN F-box only protein 8 OS=Homo sapie...1991e-17     90.5     33     50GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0000151; C:ubiquitin ligase complex; NAS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; NAS:UniProtKB.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0006511; P:ubiquitin-dependent protein catabolic process; NAS:UniProtKB.
48Q5E9G6    319   FBX8_BOVIN F-box only protein 8 OS=Bos taurus...1991e-17     90.5     33     50GO:0005737; C:cytoplasm; ISS:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; ISS:RefGenome.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
49O13817    1082   SEC7C_SCHPO Protein transport protein sec73 O...890.000000000007     74.7     40     63GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006887; P:exocytosis; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
50Q18DN4    9159   HMU_HALWD Halomucin OS=Haloquadratum walsbyi ...1720.0002     50.8     26     45GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0030246; F:carbohydrate binding; IEA:InterPro.::GO:0004180; F:carboxypeptidase activity; IEA:InterPro.
GO:0007156; P:homophilic cell adhesion; IEA:InterPro.
51Q10491    928   YDG1_SCHPO PH and SEC7 domain-containing prot...910.0000000009     67.8     33     62GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; ISS:PomBase.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006887; P:exocytosis; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
52O13690    942   YDYB_SCHPO PH and SEC7 domain-containing prot...1330.000000005     65.5     27     52GO:0005737; C:cytoplasm; ISS:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
53Q06836    1226   SYT1_YEAST Arf guanine nucleotide exchange fa...1540.0000001     60.8     27     49GO:0044431; C:Golgi apparatus part; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IDA:SGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032014; P:positive regulation of ARF protein signal transduction; IMP:SGD.::GO:0016192; P:vesicle-mediated transport; IGI:SGD.
54Q3UGY8    2170   BIG3_MOUSE Brefeldin A-inhibited guanine nucl...720.053     42.4     26     51GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
55Q9VLT1    1684   MON2_DROME Protein MON2 homolog OS=Drosophila...3510.00003     53.1     21     38GO:0005768; C:endosome; IDA:FlyBase.::GO:0005794; C:Golgi apparatus; IDA:FlyBase.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005519; F:cytoskeletal regulatory protein binding; IPI:FlyBase.
GO:0031532; P:actin cytoskeleton reorganization; IMP:FlyBase.::GO:0007318; P:pole plasm protein localization; IMP:FlyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
56Q29L43    1701   MON2_DROPS Protein MON2 homolog OS=Drosophila...3460.00005     52.4     20     38
GO:0005488; F:binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.
57Q5TH69    2177   BIG3_HUMAN Brefeldin A-inhibited guanine nucl...720.049     42.7     26     51GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
58Q19338    1646   MON2_CAEEL Monensin-resistant homolog 2 OS=Ca...4630.0004     49.7     18     38GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005488; F:binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0071688; P:striated muscle myosin thick filament assembly; IMP:WormBase.
59Q5H9L2    206   TCAL5_HUMAN Transcription elongation factor A...1192.1     36.2     28     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
60B4F777    429   HMGN5_RAT High mobility group nucleosome-bind...1081.6     37     25     45GO:0000785; C:chromatin; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
61Q80TL7    1715   MON2_MOUSE Protein MON2 homolog OS=Mus muscul...2450.67     38.9     23     41GO:0005737; C:cytoplasm; IBA:RefGenome.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005488; F:binding; IEA:InterPro.
GO:0006895; P:Golgi to endosome transport; ISS:HGNC.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
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