Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR162C
Length:
236
Number of sequences:
5887
Description:
YDR162C NBP2 SGDID:S000002569, Chr IV from 781100-780390, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex, found in the nucleus and cytoplasm, contains an SH3 domain that binds Pbs2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
271B6HR44    291   SHO1_PENCW High osmolarity signaling protein ...612.5     32.7     31     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
272A7E8B6    1150   SLA1_SCLS1 Actin cytoskeleton-regulatory comp...762.5     33.1     32     50GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
273O94868    740   FCSD2_HUMAN FCH and double SH3 domains protei...1262.6     32.7     27     39
GO:0005515; F:protein binding; IPI:IntAct.
274Q659X0    575   FUT8_CANFA Alpha-(1,6)-fucosyltransferase OS=...472.6     32.7     30     53GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008424; F:glycoprotein 6-alpha-L-fucosyltransferase activity; IEA:EC.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0033578; P:protein glycosylation in Golgi; IEA:InterPro.
275P24604    630   TEC_MOUSE Tyrosine-protein kinase Tec OS=Mus ...532.7     32.7     34     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
276Q8VCZ6    750   SGSM3_MOUSE Small G protein signaling modulat...672.7     32.7     33     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005921; C:gap junction; IDA:UniProtKB.
GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0045732; P:positive regulation of protein catabolic process; IDA:UniProtKB.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.
277Q6UXY1    529   BI2L2_HUMAN Brain-specific angiogenesis inhib...472.7     32.7     34     51GO:0044291; C:cell-cell contact zone; IDA:UniProtKB.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0016044; P:cellular membrane organization; ISS:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
278P16277    499   BLK_MOUSE Tyrosine-protein kinase Blk OS=Mus ...562.7     32.7     30     55GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
279P15498    845   VAV_HUMAN Proto-oncogene vav OS=Homo sapiens ...532.7     32.7     42     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.
280Q6P6R7    749   SGSM3_RAT Small G protein signaling modulator...672.7     32.7     33     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.
281P13115    532   SRC1_XENLA Tyrosine-protein kinase Src-1 OS=X...522.8     32.7     31     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
282Q80Y61    522   BI2L2_MOUSE Brain-specific angiogenesis inhib...472.9     32.7     34     51GO:0044291; C:cell-cell contact zone; ISS:UniProtKB.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0016044; P:cellular membrane organization; IDA:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
283Q5T0N5    605   FBP1L_HUMAN Formin-binding protein 1-like OS=...513     32.7     31     59GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
284P13116    532   SRC2_XENLA Tyrosine-protein kinase Src-2 OS=X...523.1     32.7     31     54GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
285Q12774    1597   ARHG5_HUMAN Rho guanine nucleotide exchange f...563.1     32.7     30     52GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
286P09769    529   FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo...523.2     32.7     31     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034988; F:Fc-gamma receptor I complex binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0001784; F:phosphotyrosine binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0050830; P:defense response to Gram-positive bacterium; ISS:UniProtKB.::GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; TAS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045088; P:regulation of innate immune response; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; ISS:UniProtKB.::GO:0009615; P:response to virus; TAS:ProtInc.
287Q9XYM0    271   CRK_DROME Adapter molecule Crk OS=Drosophila ...613.2     32.3     31     49
GO:0005070; F:SH3/SH2 adaptor activity; IDA:FlyBase.
GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0046529; P:imaginal disc fusion, thorax closure; IMP:FlyBase.::GO:0007520; P:myoblast fusion; TAS:FlyBase.::GO:0046330; P:positive regulation of JNK cascade; IDA:FlyBase.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB.
288Q8K3E5    1047   AHI1_MOUSE Jouberin OS=Mus musculus (Mouse). ...533.3     32.7     30     47GO:0005912; C:adherens junction; ISS:UniProtKB.::GO:0005911; C:cell-cell junction; ISS:UniProtKB.::GO:0005814; C:centriole; IDA:UniProtKB.::GO:0005932; C:microtubule basal body; IDA:UniProtKB.::GO:0036038; C:TCTN-B9D complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0042384; P:cilium assembly; IMP:UniProtKB.::GO:0035844; P:cloaca development; IGI:UniProtKB.::GO:0001947; P:heart looping; IGI:UniProtKB.::GO:0030902; P:hindbrain development; IGI:UniProtKB.::GO:0070121; P:Kupffer's vesicle development; ISS:UniProtKB.::GO:0070986; P:left/right axis specification; ISS:UniProtKB.::GO:0001738; P:morphogenesis of a polarized epithelium; IMP:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0071599; P:otic vesicle development; IGI:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; IGI:UniProtKB.::GO:0030862; P:positive regulation of polarized epithelial cell differentiation; IMP:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0039023; P:pronephric duct morphogenesis; ISS:UniProtKB.::GO:0039008; P:pronephric nephron tubule morphogenesis; IGI:UniProtKB.::GO:0033365; P:protein localization to organelle; IMP:UniProtKB.::GO:0050795; P:regulation of behavior; IMP:UniProtKB.::GO:0010842; P:retina layer formation; IGI:UniProtKB.::GO:0065001; P:specification of axis polarity; IGI:UniProtKB.::GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; IMP:UniProtKB.::GO:0016192; P:vesicle-mediated transport; IMP:UniProtKB.
289P54100    843   VAV_RAT Proto-oncogene vav OS=Rattus norvegic...533.4     32.7     42     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0048468; P:cell development; TAS:RGD.::GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; IEP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
290P27870    845   VAV_MOUSE Proto-oncogene vav OS=Mus musculus ...533.4     32.7     42     51GO:0005829; C:cytosol; TAS:Reactome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0030676; F:Rac guanyl-nucleotide exchange factor activity; IGI:MGI.
GO:0006955; P:immune response; IMP:MGI.::GO:0007229; P:integrin-mediated signaling pathway; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IMP:MGI.::GO:0006909; P:phagocytosis; IGI:MGI.::GO:0045785; P:positive regulation of cell adhesion; IGI:MGI.::GO:0043087; P:regulation of GTPase activity; IGI:MGI.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0030217; P:T cell differentiation; TAS:MGI.
291Q5NVB3    574   FUT8_PONAB Alpha-(1,6)-fucosyltransferase OS=...473.4     32.3     30     53GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008424; F:glycoprotein 6-alpha-L-fucosyltransferase activity; IEA:EC.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0033578; P:protein glycosylation in Golgi; IEA:InterPro.
292Q6EV77    575   FUT8_PANTR Alpha-(1,6)-fucosyltransferase OS=...473.4     32.3     30     53GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008424; F:glycoprotein 6-alpha-L-fucosyltransferase activity; IEA:EC.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0033578; P:protein glycosylation in Golgi; IEA:InterPro.
293Q9BYC5    575   FUT8_HUMAN Alpha-(1,6)-fucosyltransferase OS=...473.4     32.3     30     53GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008424; F:glycoprotein 6-alpha-L-fucosyltransferase activity; TAS:UniProtKB.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0001701; P:in utero embryonic development; NAS:UniProtKB.::GO:0042355; P:L-fucose catabolic process; NAS:UniProtKB.::GO:0006491; P:N-glycan processing; TAS:UniProtKB.::GO:0009312; P:oligosaccharide biosynthetic process; TAS:ProtInc.::GO:0043687; P:post-translational protein modification; TAS:Reactome.::GO:0033578; P:protein glycosylation in Golgi; IEA:InterPro.::GO:0018279; P:protein N-linked glycosylation via asparagine; TAS:Reactome.
294Q6XZF7    1577   DNMBP_HUMAN Dynamin-binding protein OS=Homo s...585.9     32     34     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
295P38479    617   ABP1_SACEX Actin-binding protein OS=Saccharom...533.6     32.3     42     53GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
296Q14155    803   ARHG7_HUMAN Rho guanine nucleotide exchange f...633.7     32.3     27     52GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0043005; C:neuron projection; IDA:BHF-UCL.::GO:0043025; C:neuronal cell body; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0043547; P:positive regulation of GTPase activity; IDA:BHF-UCL.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
297Q96HU1    749   SGSM3_HUMAN Small G protein signaling modulat...673.7     32.3     31     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; IDA:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; IEP:UniProtKB.
298Q2KI13    747   SGSM3_BOVIN Small G protein signaling modulat...673.7     32.3     31     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0017137; F:Rab GTPase binding; ISS:UniProtKB.
GO:0007050; P:cell cycle arrest; IEA:UniProtKB-KW.::GO:0032486; P:Rap protein signal transduction; ISS:UniProtKB.
299Q09746    642   BZZ1_SCHPO Protein BZZ1 OS=Schizosaccharomyce...523.9     32.3     35     58GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0007015; P:actin filament organization; ISS:PomBase.::GO:0006897; P:endocytosis; ISS:PomBase.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
300Q5U2U2    303   CRKL_RAT Crk-like protein OS=Rattus norvegicu...504.1     32     38     58
301Q8K012    605   FBP1L_MOUSE Formin-binding protein 1-like OS=...514.1     32.3     31     59GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
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