Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR162C
Length:
236
Number of sequences:
5887
Description:
YDR162C NBP2 SGDID:S000002569, Chr IV from 781100-780390, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex, found in the nucleus and cytoplasm, contains an SH3 domain that binds Pbs2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121P50478    682   AMPH_CHICK Amphiphysin OS=Gallus gallus (Chic...790.11     37.4     30     44GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:AgBase.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:AgBase.
122Q5XXR3    772   ARHG6_RAT Rho guanine nucleotide exchange fac...570.12     37     30     56GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
123Q8TE67    593   ES8L3_HUMAN Epidermal growth factor receptor ...660.12     37     27     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
124Q9CX99    217   GRAP_MOUSE GRB2-related adapter protein OS=Mu...810.13     36.2     32     47
125Q8I1A6    366   SH3G3_DROWI Endophilin-A OS=Drosophila willis...550.13     36.6     36     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB.
GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB.
126Q8I190    369   SH3G3_DROVI Endophilin-A OS=Drosophila virili...550.13     36.6     36     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB.
GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB.
127Q9QY53    687   NPHP1_MOUSE Nephrocystin-1 OS=Mus musculus (M...630.13     37     30     59GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0031514; C:motile cilium; ISS:UniProtKB.::GO:0032391; C:photoreceptor connecting cilium; IDA:UniProtKB.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0030030; P:cell projection organization; IMP:UniProtKB.::GO:0034613; P:cellular protein localization; IGI:UniProtKB.::GO:0035845; P:photoreceptor cell outer segment organization; IGI:UniProtKB.::GO:0060041; P:retina development in camera-type eye; IMP:UniProtKB.::GO:0048515; P:spermatid differentiation; IMP:UniProtKB.
128P62484    446   ABI2_MOUSE Abl interactor 2 OS=Mus musculus (...640.13     37     33     53GO:0005913; C:cell-cell adherens junction; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IDA:MGI.::GO:0030175; C:filopodium; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0016358; P:dendrite development; IMP:MGI.::GO:0007611; P:learning or memory; IMP:MGI.
129A8MVU1    366   NCF1C_HUMAN Putative neutrophil cytosol facto...710.13     36.6     30     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0016175; F:superoxide-generating NADPH oxidase activity; IEA:InterPro.
GO:0007154; P:cell communication; IEA:InterPro.
130O77775    527   NCF2_BOVIN Neutrophil cytosol factor 2 OS=Bos...552.2     33.1     35     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
131Q9NYB9    513   ABI2_HUMAN Abl interactor 2 OS=Homo sapiens (...640.14     37     33     53GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IDA:BHF-UCL.::GO:0030175; C:filopodium; IDA:UniProtKB.::GO:0030027; C:lamellipodium; IDA:UniProtKB.
GO:0008093; F:cytoskeletal adaptor activity; TAS:UniProtKB.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0019900; F:kinase binding; NAS:UniProtKB.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.
GO:0008154; P:actin polymerization or depolymerization; NAS:UniProtKB.::GO:0016477; P:cell migration; TAS:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.
132Q8I1C0    369   SH3G3_DROPS Endophilin-A OS=Drosophila pseudo...550.14     36.6     36     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0042171; F:lysophosphatidic acid acyltransferase activity; ISS:UniProtKB.
GO:0050803; P:regulation of synapse structure and activity; ISS:UniProtKB.::GO:0048488; P:synaptic vesicle endocytosis; ISS:UniProtKB.
133Q2KJB5    505   NOSTN_BOVIN Nostrin OS=Bos taurus (Bovine). G...500.14     36.6     40     52GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
134Q758Q9    1292   MYO1_ASHGO Myosin-1 OS=Y-1056) (Yeast) (Eremo...510.16     37     33     57GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
135Q7SIG6    958   ASAP2_MOUSE Arf-GAP with SH3 domain, ANK repe...580.17     36.6     31     53GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
136P19878    526   NCF2_HUMAN Neutrophil cytosol factor 2 OS=Hom...551.8     33.1     35     51GO:0043020; C:NADPH oxidase complex; TAS:BHF-UCL.::GO:0005730; C:nucleolus; IDA:HPA.::GO:0032010; C:phagolysosome; TAS:Reactome.
GO:0009055; F:electron carrier activity; TAS:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.
GO:0002479; P:antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; TAS:Reactome.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:BHF-UCL.::GO:0045730; P:respiratory burst; TAS:BHF-UCL.::GO:0042554; P:superoxide anion generation; TAS:BHF-UCL.
137Q3V3E1    624   UBS3A_MOUSE Ubiquitin-associated and SH3 doma...610.18     36.6     26     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0050860; P:negative regulation of T cell receptor signaling pathway; IGI:MGI.::GO:0001817; P:regulation of cytokine production; IGI:MGI.
138Q7TQF7    686   AMPH_MOUSE Amphiphysin OS=Mus musculus (Mouse...790.18     36.6     30     44GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0007612; P:learning; IMP:MGI.::GO:0048488; P:synaptic vesicle endocytosis; IMP:MGI.
139Q92266    380   PEX13_PICPA Peroxisomal membrane protein PEX1...630.18     36.2     38     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0016560; P:protein import into peroxisome matrix, docking; IEA:InterPro.
140Q4P3H6    1207   SLA1_USTMA Actin cytoskeleton-regulatory comp...540.18     36.6     35     57GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IEA:InterPro.::GO:0030674; F:protein binding, bridging; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
141Q7SDM3    1235   MYO1_NEUCR Myosin-1 OS=1257 / FGSC 987). GN=m...520.21     36.6     37     50GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
142P05433    440   GAGC_AVISC P47(GAG-CRK) protein OS=Avian sarc...550.21     36.2     36     58GO:0019028; C:viral capsid; IEA:InterPro.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
143P0CR78    660   HSE1_CRYNJ Class E vacuolar protein-sorting m...1090.22     36.2     27     43GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
144Q95KR7    509   LCK_SAISC Proto-oncogene tyrosine-protein kin...960.22     36.2     23     47GO:0045121; C:membrane raft; ISS:UniProtKB.::GO:0000242; C:pericentriolar material; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0004722; F:protein serine/threonine phosphatase activity; ISS:UniProtKB.::GO:0042169; F:SH2 domain binding; ISS:UniProtKB.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.::GO:0006882; P:cellular zinc ion homeostasis; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0050870; P:positive regulation of T cell activation; ISS:UniProtKB.::GO:0042493; P:response to drug; ISS:UniProtKB.::GO:0030217; P:T cell differentiation; ISS:UniProtKB.
145P49418    695   AMPH_HUMAN Amphiphysin OS=Homo sapiens (Human...780.23     36.2     31     44GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
146Q92783    540   STAM1_HUMAN Signal transducing adapter molecu...550.25     35.8     35     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0016044; P:cellular membrane organization; TAS:Reactome.::GO:0016197; P:endosome transport; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.
147Q9ULH1    1129   ASAP1_HUMAN Arf-GAP with SH3 domain, ANK repe...580.27     36.2     28     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060271; P:cilium morphogenesis; IMP:UniProtKB.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
148Q04929    305   CRK_CHICK Adapter molecule crk OS=Gallus gall...550.27     35.4     36     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0032956; P:regulation of actin cytoskeleton organization; ISS:UniProtKB.::GO:0032319; P:regulation of Rho GTPase activity; ISS:UniProtKB.
149P70297    548   STAM1_MOUSE Signal transducing adapter molecu...550.28     35.8     35     47GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
150Q9QY17    488   PACN2_RAT Protein kinase C and casein kinase ...580.28     35.8     38     52GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
151Q09822    927   CDC15_SCHPO Cell division control protein 15 ...560.29     35.8     32     48GO:0051286; C:cell tip; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0032178; C:medial membrane band; IDA:PomBase.
GO:0043495; F:protein anchor; TAS:PomBase.
GO:0030866; P:cortical actin cytoskeleton organization; IMP:PomBase.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:PomBase.::GO:0061166; P:establishment of endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site; IMP:PomBase.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051125; P:regulation of actin nucleation; IGI:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.
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