Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR159W
Length:
1301
Number of sequences:
5887
Description:
YDR159W SAC3 SGDID:S000002566, Chr IV from 771877-775782, Genome Release 64-1-1, Verified ORF, "Nuclear pore-associated protein; required for biogenesis of the small ribosomal subunit; component of TREX-2 complex (Sac3p-Thp1p-Sus1p-Cdc31p) involved in transcription elongation and mRNA export from the nucleus; involved in post-transcriptional tethering of active genes to the nuclear periphery and to non-nascent mRNP; mutant displays reduced transcription elongation in the G-less-based run-on (GLRO) assay"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P46674    1301   SAC3_YEAST Nuclear mRNA export protein SAC3 O...13010     2687     100     100GO:0005643; C:nuclear pore; IDA:SGD.::GO:0070390; C:transcription export complex 2; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0030029; P:actin filament-based process; IGI:SGD.::GO:0007067; P:mitosis; IMP:SGD.::GO:0031124; P:mRNA 3'-end processing; IMP:SGD.::GO:0006406; P:mRNA export from nucleus; IMP:SGD.::GO:0071033; P:nuclear retention of pre-mRNA at the site of transcription; IMP:SGD.::GO:0000973; P:posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery; IMP:SGD.::GO:0006611; P:protein export from nucleus; IGI:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0042274; P:ribosomal small subunit biogenesis; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006283; P:transcription-coupled nucleotide-excision repair; IMP:SGD.
2O74889    1024   SAC31_SCHPO SAC3 family protein 1 OS=Schizosa...4021e-72     266     38     56GO:0005829; C:cytosol; IDA:PomBase.::GO:0005643; C:nuclear pore; ISS:PomBase.
GO:0006406; P:mRNA export from nucleus; ISS:PomBase.::GO:0006611; P:protein export from nucleus; ISS:PomBase.::GO:0042274; P:ribosomal small subunit biogenesis; ISS:PomBase.
3Q9USI4    458   SAC32_SCHPO SAC3 family protein 2 OS=Schizosa...4346e-51     192     32     50GO:0005829; C:cytosol; IDA:PomBase.::GO:0005643; C:nuclear pore; ISS:PomBase.::GO:0005730; C:nucleolus; IDA:PomBase.
GO:0006406; P:mRNA export from nucleus; ISS:PomBase.::GO:0006611; P:protein export from nucleus; ISS:PomBase.::GO:0042274; P:ribosomal small subunit biogenesis; ISS:PomBase.
4Q9WUU9    1971   MCM3A_MOUSE 80 kDa MCM3-associated protein OS...3862e-33     145     28     47GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0000166; F:nucleotide binding; IEA:InterPro.
5O60318    1980   MCM3A_HUMAN 80 kDa MCM3-associated protein OS...4331e-32     142     27     46GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0006260; P:DNA replication; TAS:ProtInc.::GO:0006606; P:protein import into nucleus; TAS:ProtInc.
6Q9U3V9    1370   XMAS2_DROME Protein xmas-2 OS=Drosophila mela...3183e-28     127     30     45GO:0005643; C:nuclear pore; IDA:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; NAS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; NAS:UniProtKB.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0016973; P:poly(A)+ mRNA export from nucleus; IMP:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0007283; P:spermatogenesis; NAS:UniProtKB.
7A6NKF1    404   SAC31_HUMAN SAC3 domain-containing protein 1 ...3680.000000000001     74.7     23     43GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
8Q32NW2    800   LENG8_XENLA Leukocyte receptor cluster member...2630.00002     52.8     25     38
9A6H687    427   SAC31_MOUSE SAC3 domain-containing protein 1 ...3650.00003     52     24     43GO:0005813; C:centrosome; IDA:MGI.::GO:0005819; C:spindle; IDA:MGI.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0051298; P:centrosome duplication; IMP:MGI.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0051225; P:spindle assembly; IMP:MGI.
10A4QNR8    839   LENG8_DANRE Leukocyte receptor cluster member...2620.12     40.4     22     38
11A7SKJ3    531   DPH2_NEMVE Diphthamide biosynthesis protein 2...820.15     40     26     51GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0017183; P:peptidyl-diphthamide biosynthetic process from peptidyl-histidine; IEA:InterPro.
12Q54WU3    367   AMPM1_DICDI Methionine aminopeptidase 1 OS=Di...1440.51     38.1     24     40
GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
GO:0009987; P:cellular process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
13Q96PV6    779   LENG8_HUMAN Leukocyte receptor cluster member...2270.73     37.7     24     38
GO:0005515; F:protein binding; IPI:UniProtKB.
14Q9YF31    200   VATE_AERPE V-type ATP synthase subunit E OS=1...721.2     36.2     26     54GO:0033178; C:proton-transporting two-sector ATPase complex, catalytic domain; IEA:InterPro.
GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
GO:0006754; P:ATP biosynthetic process; IEA:UniProtKB-KW.::GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
15O55135    245   IF6_MOUSE Eukaryotic translation initiation f...772     35.8     35     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005638; C:lamin filament; IDA:MGI.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0043022; F:ribosome binding; ISS:UniProtKB.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0042256; P:mature ribosome assembly; ISS:UniProtKB.
16Q97K92    392   FPRA1_CLOAB Flavo-diiron protein FprA1 OS=571...1012.1     36.2     26     48
GO:0009055; F:electron carrier activity; IDA:UniProtKB.::GO:0010181; F:FMN binding; IDA:UniProtKB.::GO:0016787; F:hydrolase activity; IEA:InterPro.::GO:0005506; F:iron ion binding; IDA:UniProtKB.::GO:0050664; F:oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor; IDA:UniProtKB.
GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0072592; P:oxygen metabolic process; IDA:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
17Q3KRD8    245   IF6_RAT Eukaryotic translation initiation fac...772.2     35.4     35     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0043022; F:ribosome binding; IEA:InterPro.::GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
GO:0042256; P:mature ribosome assembly; IEA:InterPro.
18P95334    607   DNAK_MYXXD Chaperone protein DnaK OS=Myxococc...1436.1     34.7     27     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
19P04323    1058   POL3_DROME Retrovirus-related Pol polyprotein...1677.2     34.7     28     47
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.::GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:InterPro.::GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
GO:0015074; P:DNA integration; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.::GO:0006278; P:RNA-dependent DNA replication; IEA:InterPro.
20B2S0W1    208   RS4_BORHD 30S ribosomal protein S4 OS=Borreli...538.8     33.5     38     62GO:0015935; C:small ribosomal subunit; IEA:InterPro.
GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
21B5RPW0    208   RS4_BORRA 30S ribosomal protein S4 OS=Borreli...539.5     33.5     36     62GO:0015935; C:small ribosomal subunit; IEA:InterPro.
GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
22A1R043    208   RS4_BORT9 30S ribosomal protein S4 OS=Borreli...539.6     33.5     36     62GO:0015935; C:small ribosomal subunit; IEA:InterPro.
GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
23Q8CBY3    785   LENG8_MOUSE Leukocyte receptor cluster member...2209.6     34.3     25     38
24Q92355    1687   SEN1_SCHPO Helicase sen1 OS=Schizosaccharomyc...1229.6     34.3     27     45GO:0035649; C:Nrd1 complex; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IC:PomBase.::GO:0043141; F:ATP-dependent 5'-3' DNA helicase activity; IDA:PomBase.::GO:0032575; F:ATP-dependent 5'-3' RNA helicase activity; IDA:PomBase.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006364; P:rRNA processing; ISS:PomBase.::GO:0043144; P:snoRNA processing; ISS:PomBase.::GO:0016180; P:snRNA processing; ISS:PomBase.::GO:0006369; P:termination of RNA polymerase II transcription; ISS:PomBase.::GO:0008033; P:tRNA processing; ISS:PomBase.
records
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