Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR151C
Length:
325
Number of sequences:
5887
Description:
YDR151C CTH1 SGDID:S000002558, Chr IV from 765155-764178, Genome Release 64-1-1, reverse complement, Verified ORF, "Member of the CCCH zinc finger family; has similarity to mammalian Tis11 protein, which activates transcription and also has a role in mRNA degradation; may function with Tis11p in iron homeostasis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P47976    325   CTH1_YEAST mRNA decay factor CTH1 OS=Saccharo...3250     665     100     100GO:0005634; C:nucleus; IC:SGD.
GO:0003729; F:mRNA binding; ISS:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006879; P:cellular iron ion homeostasis; IGI:SGD.::GO:0000956; P:nuclear-transcribed mRNA catabolic process; IGI:SGD.
2P47977    285   CTH2_YEAST mRNA decay factor CTH2 OS=Saccharo...2924e-49     171     43     58GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0003729; F:mRNA binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006879; P:cellular iron ion homeostasis; IMP:SGD.::GO:0000956; P:nuclear-transcribed mRNA catabolic process; IMP:SGD.
3P47980    436   TIS1_DROME Protein TIS11 OS=Drosophila melano...872e-18     89     47     61GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016246; P:RNA interference; IMP:FlyBase.
4Q7ZXW9    363   TISDA_XENLA Zinc finger protein 36, C3H1 type...410.004     42     41     54GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; ISS:UniProtKB.::GO:0048793; P:pronephros development; ISS:UniProtKB.::GO:0043488; P:regulation of mRNA stability; ISS:UniProtKB.
5P23950    338   TISB_MOUSE Zinc finger protein 36, C3H1 type-...410.004     42.4     41     54GO:0005634; C:nucleus; IDA:MGI.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IDA:MGI.::GO:0006417; P:regulation of translation; IMP:MGI.::GO:0033077; P:T cell differentiation in thymus; IGI:BHF-UCL.::GO:0001570; P:vasculogenesis; IMP:MGI.
6P17431    338   TISB_RAT Zinc finger protein 36, C3H1 type-li...410.004     42.4     41     54GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0017091; F:AU-rich element binding; IMP:RGD.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003729; F:mRNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
7Q07352    338   TISB_HUMAN Zinc finger protein 36, C3H1 type-...410.004     42     41     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003729; F:mRNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010467; P:gene expression; TAS:Reactome.::GO:0043488; P:regulation of mRNA stability; IDA:MGI.
8Q805B4    364   TISDB_XENLA Zinc finger protein 36, C3H1 type...410.004     42     41     54GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; ISS:UniProtKB.::GO:0039020; P:pronephric nephron tubule development; IMP:UniProtKB.::GO:0043488; P:regulation of mRNA stability; ISS:UniProtKB.
9P47979    404   ZFS1_SCHPO Zinc finger protein zfs1 OS=Schizo...732e-17     85.5     48     68GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0035925; F:mRNA 3'-UTR AU-rich region binding; IDA:PomBase.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IGI:PomBase.::GO:0006402; P:mRNA catabolic process; IMP:PomBase.::GO:0031030; P:negative regulation of septation initiation signaling cascade; IGI:PomBase.::GO:0000750; P:pheromone-dependent signal transduction involved in conjugation with cellular fusion; IMP:PomBase.::GO:0031137; P:regulation of conjugation with cellular fusion; IGI:PomBase.
10P47974    494   TISD_HUMAN Zinc finger protein 36, C3H1 type-...410.003     42.7     41     56
11P23949    367   TISD_MOUSE Zinc finger protein 36, C3H1 type-...410.006     41.6     41     56GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; IDA:MGI.::GO:0043488; P:regulation of mRNA stability; IDA:MGI.::GO:0033077; P:T cell differentiation in thymus; IGI:BHF-UCL.
12A4IIN5    333   TISD_XENTR Zinc finger protein 36, C3H1 type-...410.02     40     39     51GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000288; P:nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay; ISS:UniProtKB.::GO:0048793; P:pronephros development; ISS:UniProtKB.::GO:0043488; P:regulation of mRNA stability; ISS:UniProtKB.
13Q6S9E0    325   TTP_SHEEP Tristetraprolin OS=Ovis aries (Shee...697e-16     80.1     49     64GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0017091; F:AU-rich element binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; ISS:UniProtKB.::GO:0006402; P:mRNA catabolic process; ISS:UniProtKB.::GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; ISS:UniProtKB.::GO:0032680; P:regulation of tumor necrosis factor production; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB.
14P26651    326   TTP_HUMAN Tristetraprolin OS=Homo sapiens (Hu...698e-16     80.1     49     64GO:0010494; C:cytoplasmic stress granule; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0071889; F:14-3-3 protein binding; IDA:UniProtKB.::GO:0017091; F:AU-rich element binding; IDA:UniProtKB.::GO:0019957; F:C-C chemokine binding; IPI:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003729; F:mRNA binding; IDA:MGI.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0003727; F:single-stranded RNA binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; IDA:UniProtKB.::GO:0032680; P:regulation of tumor necrosis factor production; IDA:UniProtKB.::GO:0006950; P:response to stress; IDA:UniProtKB.
15P53781    324   TTP_BOVIN Tristetraprolin OS=Bos taurus (Bovi...690.000000000000001     79.7     49     64GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0017091; F:AU-rich element binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; ISS:UniProtKB.::GO:0006402; P:mRNA catabolic process; ISS:UniProtKB.::GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; ISS:UniProtKB.::GO:0032680; P:regulation of tumor necrosis factor production; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB.
16P22893    319   TTP_MOUSE Tristetraprolin OS=Mus musculus (Mo...710.000000000000003     78.6     46     63GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0017091; F:AU-rich element binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003729; F:mRNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:MGI.::GO:0050728; P:negative regulation of inflammatory response; IMP:UniProtKB.::GO:0045638; P:negative regulation of myeloid cell differentiation; IMP:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; IDA:MGI.::GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; ISS:UniProtKB.::GO:0032680; P:regulation of tumor necrosis factor production; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB.::GO:0050779; P:RNA destabilization; IMP:MGI.
17P47973    320   TTP_RAT Tristetraprolin OS=Rattus norvegicus ...710.00000000000003     75.5     45     62GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0071889; F:14-3-3 protein binding; ISS:UniProtKB.::GO:0017091; F:AU-rich element binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070935; P:3'-UTR-mediated mRNA stabilization; ISS:UniProtKB.::GO:0060213; P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:RGD.::GO:0032680; P:regulation of tumor necrosis factor production; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB.
18Q6L5G1    343   C3H39_ORYSJ Zinc finger CCCH domain-containin...370.89     34.7     32     54
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
19A2ZVY5    333   C3H9_ORYSJ Zinc finger CCCH domain-containing...375.3     32.3     32     49
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
20Q9C9N3    310   C3H14_ARATH Zinc finger CCCH domain-containin...332.8     33.1     36     52
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
21Q10MN8    457   C3H21_ORYSJ Putative zinc finger CCCH domain-...355.1     32.7     34     51
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
22Q9C9F5    308   C3H15_ARATH Zinc finger CCCH domain-containin...390.66     35     36     54
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.
23Q9XUB2    468   MEX5_CAEEL Zinc finger protein mex-5 OS=Caeno...1280.0000000002     65.1     34     51GO:0005813; C:centrosome; IDA:WormBase.::GO:0043186; C:P granule; IDA:WormBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003730; F:mRNA 3'-UTR binding; IDA:WormBase.::GO:0008187; F:poly-pyrimidine tract binding; IDA:WormBase.::GO:0019904; F:protein domain specific binding; IPI:WormBase.::GO:0019901; F:protein kinase binding; IPI:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0032880; P:regulation of protein localization; IMP:WormBase.
24Q09436    467   MEX6_CAEEL Zinc finger protein mex-6 OS=Caeno...1270.000000008     60.1     32     48GO:0043186; C:P granule; IDA:WormBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003730; F:mRNA 3'-UTR binding; IDA:WormBase.::GO:0019904; F:protein domain specific binding; IPI:WormBase.::GO:0019901; F:protein kinase binding; IPI:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0032880; P:regulation of protein localization; IGI:WormBase.
25A3BUD2    605   C3H57_ORYSJ Putative zinc finger CCCH domain-...610.000002     52.8     36     54
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
26Q5PP65    252   C3H28_ARATH Zinc finger CCCH domain-containin...390.011     40.4     38     59
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.
27Q8GVZ8    496   C3H48_ORYSJ Putative zinc finger CCCH domain-...890.009     41.2     26     43
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
28Q94131    335   PIE1_CAEEL Pharynx and intestine in excess pr...350.068     38.1     40     57GO:0005813; C:centrosome; IDA:WormBase.::GO:0005829; C:cytosol; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.::GO:0043186; C:P granule; IDA:WormBase.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001709; P:cell fate determination; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0009880; P:embryonic pattern specification; IMP:WormBase.::GO:0001704; P:formation of primary germ layer; IMP:WormBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29Q9LT81    386   C3H39_ARATH Zinc finger CCCH domain-containin...1520.24     36.6     19     36
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.
30Q7F8R0    300   C3H14_ORYSJ Zinc finger CCCH domain-containin...311.4     33.9     45     74
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
31Q9LQM3    384   C3H12_ARATH Zinc finger CCCH domain-containin...381.7     33.9     39     55
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.
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