Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR144C
Length:
596
Number of sequences:
5887
Description:
YDR144C MKC7 SGDID:S000002551, Chr IV from 746101-744311, Genome Release 64-1-1, reverse complement, Verified ORF, "GPI-anchored aspartyl protease, member of the yapsin family of proteases involved in cell wall growth and maintenance; shares functions with Yap3p and Kex2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q6IE75    514   BACE2_RAT Beta-secretase 2 OS=Rattus norvegic...3040.00001     51.6     24     40GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB.
GO:0006509; P:membrane protein ectodomain proteolysis; ISS:UniProtKB.::GO:0042985; P:negative regulation of amyloid precursor protein biosynthetic process; ISS:UniProtKB.
152P00795    345   CATD_PIG Cathepsin D OS=Sus scrofa (Pig). GN=...270.032     40.4     67     78GO:0005615; C:extracellular space; IDA:BHF-UCL.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
153D4AZK1    509   CTSD_ARTBC Probable aspartic-type endopeptida...4060.00002     51.2     22     37GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
154Q29078    389   PAG1_PIG Pregnancy-associated glycoprotein 1 ...2190.00002     50.8     24     42GO:0005615; C:extracellular space; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
155P85138    266   CARDG_CYNCA Cardosin-G OS=Cynara cardunculus ...410.001     45.1     59     73GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0000326; C:protein storage vacuole; IEA:UniProtKB-SubCell.::GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
156D4D8U6    509   CTSD_TRIVH Probable aspartic-type endopeptida...4060.00003     50.8     22     37GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
157Q2HJ40    501   BACE1_BOVIN Beta-secretase 1 OS=Bos taurus (B...3400.00004     50.1     21     38GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.
158P56819    501   BACE1_RAT Beta-secretase 1 OS=Rattus norvegic...3400.00004     50.1     21     38GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.
159P85139    265   CARDH_CYNCA Cardosin-H OS=Cynara cardunculus ...410.001     45.1     59     73GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0000326; C:protein storage vacuole; IEA:UniProtKB-SubCell.::GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
160P56818    501   BACE1_MOUSE Beta-secretase 1 OS=Mus musculus ...3080.00007     49.3     21     39GO:0030424; C:axon; IDA:MGI.::GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005624; C:membrane fraction; IDA:MGI.
GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.
161P56817    501   BACE1_HUMAN Beta-secretase 1 OS=Homo sapiens ...3400.00007     49.3     21     38GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.::GO:0008798; F:beta-aspartyl-peptidase activity; TAS:ProtInc.::GO:0019899; F:enzyme binding; IPI:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; IDA:UniProtKB.::GO:0006509; P:membrane protein ectodomain proteolysis; TAS:UniProtKB.
162P42210    508   ASPR_HORVU Phytepsin OS=Hordeum vulgare (Barl...780.0001     48.9     36     58GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006629; P:lipid metabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
163A1DDK1    395   PEPA_NEOFI Aspartic protease pep1 OS=181) (As...1800.0002     47.8     28     45GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
164Q69IF8    406   PEPA_PHANO Aspartic protease PEP1 OS=(Glume b...2850.0002     47.8     24     40GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
165P53057    165   YPS5_YEAST Yapsin-5 OS=Saccharomyces cerevisi...350.0002     45.8     54     74
GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
166P42211    496   ASPRX_ORYSJ Aspartic proteinase OS=Oryza sati...2500.0002     47.8     23     40
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006629; P:lipid metabolic process; IEA:InterPro.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
167C5FW52    388   Y6955_ARTOC Probable aspartic-type endopeptid...1760.0002     47.4     28     44GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
168P41748    395   PEPA_ASPFU Aspartic protease pep1 OS=A1100) (...1810.0004     47     28     45GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
169B0Y1V8    395   PEPA_ASPFC Aspartic protease pep1 OS=(Aspergi...1810.0004     47     28     45GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
170Q3E740    77   YG258_YEAST Uncharacterized protein YGL258W-A...480.0005     43.5     48     60
GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
171P85136    224   CARDE_CYNCA Cardosin-E OS=Cynara cardunculus ...2560.014     41.2     24     39GO:0005618; C:cell wall; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IEA:UniProtKB-SubCell.::GO:0000326; C:protein storage vacuole; IEA:UniProtKB-SubCell.::GO:0005578; C:proteinaceous extracellular matrix; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
172P09177    427   CARP_RHIPU Mucorpepsin OS=Rhizomucor pusillus...690.16     38.5     36     54
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
173C5FEK4    377   CTSD_ARTOC Probable aspartic-type endopeptida...3110.004     43.5     21     38GO:0031225; C:anchored to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
174Q1KLR6    473   BACE1_CAVPO Beta-secretase 1 OS=Cavia porcell...520.005     43.5     35     62GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; ISS:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; ISS:UniProtKB.::GO:0006508; P:proteolysis; ISS:UniProtKB.
175P00798    323   PENP_PENJA Penicillopepsin OS=Penicillium jan...2870.006     42.7     26     40
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
176Q12567    394   PEPA_ASPSA Aspartic protease pep1 OS=Aspergil...1130.014     41.6     28     50GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
177P55325    394   PEPA_ASPNG Aspartic protease pep1 OS=Aspergil...1130.018     41.2     28     50GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
178P11838    419   CARP_CRYPA Endothiapepsin OS=parasitica). GN=...3990.021     41.2     24     38
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
179A2R3L3    394   PEPA_ASPNC Aspartic protease pep1 OS=Aspergil...1130.023     41.2     28     49GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
180Q766C3    437   NEP1_NEPGR Aspartic proteinase nepenthesin-1 ...4080.027     40.8     22     38GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:UniProtKB-KW.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
181P78735    394   PEPA_PENJA Aspartic protease pepA OS=Penicill...1910.038     40.4     28     42GO:0005576; C:extracellular region; IDA:UniProtKB.
GO:0004190; F:aspartic-type endopeptidase activity; IDA:UniProtKB.
GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
records
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