Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR143C
Length:
610
Number of sequences:
5887
Description:
YDR143C SAN1 SGDID:S000002550, Chr IV from 743874-742042, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-protein ligase; involved in the proteasome-dependent degradation of aberrant nuclear proteins; targets substrates with regions of exposed hydrophobicity containing 5 or more contiguous hydrophobic residues; contains intrinsically disordered regions that contribute to substrate recognition"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61A8Y4B2    622   HRD1_CAEBR E3 ubiquitin-protein ligase hrd-1 ...350.011     42.4     40     60GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
62Q6DIP3    311   RN126_XENTR RING finger protein 126 OS=Xenopu...310.011     42     42     68
GO:0008270; F:zinc ion binding; IEA:InterPro.
63Q6IV57    230   RN141_RAT RING finger protein 141 OS=Rattus n...500.012     41.2     36     56
GO:0008270; F:zinc ion binding; IEA:InterPro.
64Q91YL2    313   RN126_MOUSE RING finger protein 126 OS=Mus mu...610.012     41.6     31     54
GO:0008270; F:zinc ion binding; IEA:InterPro.
65Q6GPV5    156   RN181_XENLA E3 ubiquitin-protein ligase RNF18...300.013     40.4     50     63
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
66Q7T0Q3    312   R126A_XENLA RING finger protein 126-A OS=Xeno...310.013     41.6     42     68
GO:0008270; F:zinc ion binding; IEA:InterPro.
67Q6AY01    381   RN133_RAT E3 ubiquitin-protein ligase RNF133 ...800.014     42     30     48GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
68Q20798    610   HRD1_CAEEL E3 ubiquitin-protein ligase hrd-1 ...350.014     42     40     60GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
69Q6R567    252   RMA1_CAPAN E3 ubiquitin-protein ligase RMA1H1...510.015     41.2     35     51GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009723; P:response to ethylene stimulus; IEP:UniProtKB.::GO:0006970; P:response to osmotic stress; IEP:UniProtKB.::GO:0009414; P:response to water deprivation; IEP:UniProtKB.::GO:0009611; P:response to wounding; IEP:UniProtKB.
70Q9LT17    340   BBR_ARATH E3 ubiquitin ligase BIG BROTHER-rel...340.016     41.6     41     59
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.
71Q9UKV5    643   AMFR2_HUMAN E3 ubiquitin-protein ligase AMFR ...300.016     42     47     60GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0000299; C:integral to membrane of membrane fraction; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:UniProtKB.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.::GO:0051259; P:protein oligomerization; IDA:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
72Q7ZW78    156   RN181_DANRE E3 ubiquitin-protein ligase RNF18...620.017     40     29     45
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
73O55176    578   PJA1_MOUSE E3 ubiquitin-protein ligase Praja-...720.017     41.6     28     44GO:0005737; C:cytoplasm; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030163; P:protein catabolic process; IDA:MGI.
74Q9H9V4    155   RN122_HUMAN RING finger protein 122 OS=Homo s...300.018     39.7     43     63GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
75Q5RBT7    664   RN139_PONAB E3 ubiquitin-protein ligase RNF13...280.02     41.6     43     68GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
76Q8WU17    664   RN139_HUMAN E3 ubiquitin-protein ligase RNF13...280.02     41.6     43     68GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004872; F:receptor activity; TAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0017148; P:negative regulation of translation; IDA:UniProtKB.::GO:0060628; P:regulation of ER to Golgi vesicle-mediated transport; IDA:UniProtKB.::GO:0070613; P:regulation of protein processing; IDA:UniProtKB.::GO:0031396; P:regulation of protein ubiquitination; IDA:UniProtKB.
77Q9R049    643   AMFR_MOUSE E3 ubiquitin-protein ligase AMFR O...300.02     41.6     47     60GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
78Q08109    551   HRD1_YEAST ERAD-associated E3 ubiquitin-prote...370.021     41.6     38     54GO:0000839; C:Hrd1p ubiquitin ligase ERAD-L complex; IDA:SGD.::GO:0000838; C:Hrd1p ubiquitin ligase ERAD-M complex; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; IPI:SGD.::GO:0031505; P:fungal-type cell wall organization; IGI:SGD.
79Q9LZJ6    257   ATL5_ARATH RING-H2 finger protein ATL5 OS=Ara...530.022     40.8     38     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006461; P:protein complex assembly; TAS:TAIR.
80Q8BFW4    522   TRI65_MOUSE Tripartite motif-containing prote...470.022     41.2     43     49
GO:0008270; F:zinc ion binding; IEA:InterPro.
81Q84TF5    174   RHA4A_ARATH RING-H2 zinc finger protein RHA4a...510.023     39.7     37     55
GO:0008270; F:zinc ion binding; IEA:InterPro.
82Q6IV56    222   RN141_DANRE RING finger protein 141 OS=Danio ...500.023     40.4     36     56
GO:0008270; F:zinc ion binding; IEA:InterPro.
83Q7TMV1    668   RN139_MOUSE E3 ubiquitin-protein ligase RNF13...280.024     41.2     43     68GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031396; P:regulation of protein ubiquitination; ISS:UniProtKB.
84Q5DTZ6    437   RN150_MOUSE RING finger protein 150 OS=Mus mu...350.025     41.2     34     63GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
85Q5R4R1    708   PJA2_PONAB E3 ubiquitin-protein ligase Praja-...850.025     41.2     26     42GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0034236; F:protein kinase A catalytic subunit binding; ISS:UniProtKB.::GO:0034237; F:protein kinase A regulatory subunit binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007616; P:long-term memory; ISS:UniProtKB.::GO:0010738; P:regulation of protein kinase A signaling cascade; ISS:UniProtKB.
86Q9ULK6    438   RN150_HUMAN RING finger protein 150 OS=Homo s...350.025     41.2     34     63GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
87Q8L649    248   BB_ARATH E3 ubiquitin ligase BIG BROTHER OS=A...310.026     40.4     39     61
GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048437; P:floral organ development; IMP:TAIR.::GO:0046621; P:negative regulation of organ growth; IMP:TAIR.::GO:0051865; P:protein autoubiquitination; IDA:TAIR.
88P29129    410   ICP0_SUHVF E3 ubiquitin-protein ligase ICP0 O...300.027     40.8     40     63
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
89O43164    708   PJA2_HUMAN E3 ubiquitin-protein ligase Praja-...850.027     41.2     26     42GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0034236; F:protein kinase A catalytic subunit binding; IMP:UniProtKB.::GO:0034237; F:protein kinase A regulatory subunit binding; IMP:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007616; P:long-term memory; ISS:UniProtKB.::GO:0010738; P:regulation of protein kinase A signaling cascade; IMP:UniProtKB.
90Q8NG27    643   PJA1_HUMAN E3 ubiquitin-protein ligase Praja-...720.027     41.2     28     44
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
91Q80U04    707   PJA2_MOUSE E3 ubiquitin-protein ligase Praja-...790.027     41.2     25     43GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.
GO:0034236; F:protein kinase A catalytic subunit binding; ISS:UniProtKB.::GO:0034237; F:protein kinase A regulatory subunit binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007616; P:long-term memory; ISS:UniProtKB.::GO:0010738; P:regulation of protein kinase A signaling cascade; ISS:UniProtKB.
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