Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR143C
Length:
610
Number of sequences:
5887
Description:
YDR143C SAN1 SGDID:S000002550, Chr IV from 743874-742042, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-protein ligase; involved in the proteasome-dependent degradation of aberrant nuclear proteins; targets substrates with regions of exposed hydrophobicity containing 5 or more contiguous hydrophobic residues; contains intrinsically disordered regions that contribute to substrate recognition"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301Q8LFY8    413   ATL54_ARATH RING-H2 finger protein ATL54 OS=A...553.2     34.3     35     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
302Q0WX00    460   RNG1B_ARATH Putative E3 ubiquitin-protein lig...283.2     34.3     54     61GO:0035102; C:PRC1 complex; IPI:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001709; P:cell fate determination; IMP:UniProtKB.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0010076; P:maintenance of floral meristem identity; IMP:UniProtKB.::GO:0010077; P:maintenance of inflorescence meristem identity; IMP:UniProtKB.::GO:0010492; P:maintenance of shoot apical meristem identity; IMP:UniProtKB.::GO:0045814; P:negative regulation of gene expression, epigenetic; IGI:TAIR.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IGI:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
303Q9JIT1    368   RNF32_MOUSE RING finger protein 32 OS=Mus mus...703.3     34.3     29     47
GO:0008270; F:zinc ion binding; IEA:InterPro.
304Q62191    470   RO52_MOUSE E3 ubiquitin-protein ligase TRIM21...333.3     34.3     42     67GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; ISS:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
305Q9SRQ8    356   ATL51_ARATH RING-H2 finger protein ATL51 OS=A...533.4     34.3     34     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0080167; P:response to karrikin; IEP:TAIR.
306P38239    180   YBR2_YEAST Uncharacterized RING finger protei...323.4     33.5     41     56
GO:0008270; F:zinc ion binding; IEA:InterPro.
307Q9M0R4    357   ATL37_ARATH Putative RING-H2 finger protein A...583.4     34.3     31     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
308Q9M9L0    84   APC11_ARATH Anaphase-promoting complex subuni...293.4     32     41     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
309Q9C7I1    327   ATL34_ARATH RING-H2 finger protein ATL34 OS=A...513.5     33.9     31     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
310Q6PCD5    774   RFWD3_HUMAN E3 ubiquitin-protein ligase RFWD3...503.6     34.3     34     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0070215; F:MDM2 binding; IPI:UniProtKB.::GO:0002039; F:p53 binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; IMP:UniProtKB.::GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
311Q9LSW9    375   ATL16_ARATH RING-H2 finger protein ATL16 OS=A...283.8     33.9     43     64GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
312Q17RB8    773   LONF1_HUMAN LON peptidase N-terminal domain a...933.9     34.3     24     42
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
313Q865W2    486   TRI50_PIG E3 ubiquitin-protein ligase TRIM50 ...384.1     33.9     39     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
314Q4VBT5    439   MKRN1_DANRE Probable E3 ubiquitin-protein lig...464.2     33.9     39     52
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
315Q5D7H7    547   TRIM5_LAGLA Tripartite motif-containing prote...724.3     33.9     40     50GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
316Q9LZV8    159   ATL74_ARATH RING-H2 finger protein ATL74 OS=A...304.6     32.7     43     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
317Q8CBG9    286   RN170_MOUSE RING finger protein 170 OS=Mus mu...434.8     33.5     35     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
318P0C034    251   ATL10_ARATH RING-H2 finger protein ATL10 OS=A...845     33.5     25     35GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
319Q8GT74    241   NIP2_ARATH NEP1-interacting protein 2 OS=Arab...465.1     33.1     33     46GO:0009535; C:chloroplast thylakoid membrane; IDA:TAIR.::GO:0031351; C:integral to plastid membrane; IDA:TAIR.
GO:0005515; F:protein binding; IPI:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009299; P:mRNA transcription; IPI:TAIR.::GO:0009416; P:response to light stimulus; IEP:TAIR.
320Q8VC56    488   RNF8_MOUSE E3 ubiquitin-protein ligase RNF8 O...365.2     33.9     36     53GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; IMP:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; IMP:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; IMP:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
321Q5D7I2    494   TRIM5_PITPI Tripartite motif-containing prote...355.2     33.9     51     60GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
322Q5BN31    494   TRIM5_SAIBB Tripartite motif-containing prote...355.4     33.5     51     60GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
323Q5D7I0    494   TRIM5_SAISC Tripartite motif-containing prote...355.5     33.5     51     60GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
324Q9D4H7    753   LONF3_MOUSE LON peptidase N-terminal domain a...955.6     33.9     23     45
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
325P93823    381   ATL1_ARATH RING-H2 finger protein ATL1 OS=Ara...285.7     33.5     43     61GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
326Q6DBN5    363   PUB62_ARATH U-box domain-containing protein 6...495.7     33.5     35     53GO:0000151; C:ubiquitin ligase complex; IEA:InterPro.
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.
327P22681    906   CBL_HUMAN E3 ubiquitin-protein ligase CBL OS=...296.2     33.5     41     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0001784; F:phosphotyrosine binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:HGNC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:HGNC.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:BHF-UCL.::GO:0048260; P:positive regulation of receptor-mediated endocytosis; TAS:HGNC.
328O64762    302   ATL38_ARATH RING-H2 finger protein ATL38 OS=A...337     33.1     36     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
329Q5D7H8    494   TRIM5_CALDO Tripartite motif-containing prote...357.3     33.1     51     60GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
330Q9ULV8    474   CBLC_HUMAN Signal transduction protein CBL-C ...477.9     33.1     34     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005154; F:epidermal growth factor receptor binding; IDA:BHF-UCL.::GO:0001784; F:phosphotyrosine binding; IDA:BHF-UCL.::GO:0017124; F:SH3 domain binding; IDA:BHF-UCL.::GO:0004871; F:signal transducer activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0007166; P:cell surface receptor signaling pathway; IEA:InterPro.::GO:0007175; P:negative regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:BHF-UCL.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.
331Q5D7I1    547   TRIM5_ATEGE Tripartite motif-containing prote...358     33.1     51     60GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
records
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