Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR143C
Length:
610
Number of sequences:
5887
Description:
YDR143C SAN1 SGDID:S000002550, Chr IV from 743874-742042, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-protein ligase; involved in the proteasome-dependent degradation of aberrant nuclear proteins; targets substrates with regions of exposed hydrophobicity containing 5 or more contiguous hydrophobic residues; contains intrinsically disordered regions that contribute to substrate recognition"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
241Q587N7    515   TRIM5_CHLAE Tripartite motif-containing prote...361.2     35.8     50     61GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
242A8WWR3    578   HRDL1_CAEBR E3 ubiquitin-protein ligase hrd-l...301.2     35.8     43     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043526; P:neuroprotection; ISS:UniProtKB.
243Q96EQ8    232   RN125_HUMAN E3 ubiquitin-protein ligase RNF12...571.2     35     35     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
244Q95KF1    232   RN125_MACFA E3 ubiquitin-protein ligase RNF12...791.2     35     30     42GO:0005622; C:intracellular; IEA:InterPro.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
245O00237    685   RN103_HUMAN E3 ubiquitin-protein ligase RNF10...281.3     35.8     46     64GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.
246Q9FKA7    617   ORTH1_ARATH E3 ubiquitin-protein ligase ORTHR...391.3     35.8     41     56GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0008327; F:methyl-CpG binding; IDA:TAIR.::GO:0010428; F:methyl-CpNpG binding; IDA:TAIR.::GO:0010429; F:methyl-CpNpN binding; IDA:TAIR.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0010424; P:DNA methylation on cytosine within a CG sequence; IMP:UniProtKB.::GO:0090309; P:positive regulation of methylation-dependent chromatin silencing; IMP:UniProtKB.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR.
247Q8LGA5    368   ATL31_ARATH E3 ubiquitin-protein ligase ATL31...471.3     35.4     32     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043562; P:cellular response to nitrogen levels; IMP:TAIR.::GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0009737; P:response to abscisic acid stimulus; IEP:UniProtKB.::GO:0010200; P:response to chitin; IEP:TAIR.
248Q5RAG4    444   RNFT2_PONAB RING finger and transmembrane dom...291.4     35.4     45     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
249Q9HCM9    518   TRI39_HUMAN Tripartite motif-containing prote...371.5     35.4     41     57GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
250Q1XHU0    518   TRI39_PANTR Tripartite motif-containing prote...371.5     35.4     41     57GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
251Q5R4I2    486   RNF8_PONAB E3 ubiquitin-protein ligase RNF8 O...361.5     35.4     36     53GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
252O76064    485   RNF8_HUMAN E3 ubiquitin-protein ligase RNF8 O...371.5     35.4     35     51GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; IDA:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; IDA:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; IDA:UniProtKB.::GO:0010212; P:response to ionizing radiation; IDA:UniProtKB.
253Q6MFZ5    488   TRI39_RAT Tripartite motif-containing protein...371.5     35.4     41     57GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
254Q5D7I3    495   TRIM5_ERYPA Tripartite motif-containing prote...361.5     35.4     50     61GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
255Q9FGJ6    166   ATL79_ARATH RING-H2 finger protein ATL79 OS=A...271.6     34.3     48     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
256Q2HJ46    487   RNF8_BOVIN E3 ubiquitin-protein ligase RNF8 O...361.6     35.4     36     53GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
257Q9ESN2    488   TRI39_MOUSE Tripartite motif-containing prote...371.6     35.4     41     57GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
258Q9FL42    159   ATL69_ARATH Putative RING-H2 finger protein A...301.6     34.3     40     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
259Q9ZT50    155   RHA2A_ARATH E3 ubiquitin-protein ligase RHA2A...311.7     33.9     42     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0009789; P:positive regulation of abscisic acid mediated signaling pathway; IMP:TAIR.::GO:0047484; P:regulation of response to osmotic stress; IMP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR.
260Q570X5    261   ATL58_ARATH RING-H2 finger protein ATL58 OS=A...461.7     34.7     33     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
261Q9LRB7    325   EL5_ORYSJ E3 ubiquitin-protein ligase EL5 OS=...271.8     35     52     63GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IMP:UniProtKB.::GO:0048364; P:root development; IMP:UniProtKB.
262Q1MTR5    556   YG66_SCHPO Uncharacterized RING finger membra...441.8     35.4     43     61GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0000324; C:fungal-type vacuole; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
263Q5D7I6    551   TRIM5_ALOSA Tripartite motif-containing prote...321.8     35     56     66GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
264Q9P1Y6    1649   PHRF1_HUMAN PHD and RING finger domain-contai...241.9     35.4     50     67
GO:0070063; F:RNA polymerase binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
265Q04781    1562   LTN1_YEAST E3 ubiquitin-protein ligase lister...381.9     35.4     45     55GO:0005634; C:nucleus; IDA:SGD.
GO:0043022; F:ribosome binding; IDA:SGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:SGD.
266Q9C7E9    299   ATL20_ARATH RING-H2 finger protein ATL20 OS=A...242     34.7     46     71GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
267Q28DS3    257   RN170_XENTR RING finger protein 170 OS=Xenopu...602     34.7     28     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
268Q9LUL6    204   ATL61_ARATH Putative RING-H2 finger protein A...312     34.3     42     65GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
269P33288    501   RAD18_NEUCR Postreplication repair E3 ubiquit...882     35     27     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
270Q9FHG8    210   ATL50_ARATH Putative RING-H2 finger protein A...242     34.3     50     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
271Q93Z92    390   RING4_ARATH E3 ubiquitin-protein ligase At4g1...302.1     35     47     60GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
records
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