Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR143C
Length:
610
Number of sequences:
5887
Description:
YDR143C SAN1 SGDID:S000002550, Chr IV from 743874-742042, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-protein ligase; involved in the proteasome-dependent degradation of aberrant nuclear proteins; targets substrates with regions of exposed hydrophobicity containing 5 or more contiguous hydrophobic residues; contains intrinsically disordered regions that contribute to substrate recognition"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211O74349    1610   LTN1_SCHPO E3 ubiquitin-protein ligase lister...750.64     37     35     47GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006342; P:chromatin silencing; NAS:PomBase.::GO:0070481; P:nuclear-transcribed mRNA catabolic process, non-stop decay; ISS:PomBase.
212O22755    185   ATL44_ARATH RING-H2 finger protein ATL44 OS=A...440.64     35.8     43     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
213Q8CIK8    774   RFWD3_MOUSE E3 ubiquitin-protein ligase RFWD3...380.64     37     42     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0070215; F:MDM2 binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031571; P:mitotic cell cycle G1/S transition DNA damage checkpoint; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
214P0C041    310   ATL53_ARATH Putative RING-H2 finger protein A...270.66     36.2     48     63GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
215Q54S31    374   PEX10_DICDI Peroxisome biogenesis factor 10 O...330.74     36.2     42     55GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0008270; F:zinc ion binding; ISS:dictyBase.
GO:0016558; P:protein import into peroxisome matrix; IEA:InterPro.
216O49691    289   ATL29_ARATH RING-H2 finger protein ATL29 OS=A...270.77     36.2     41     63GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
217Q9FIR0    289   ATL30_ARATH RING-H2 finger protein ATL30 OS=A...270.81     35.8     41     67GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
218Q0IJ20    695   RN145_XENTR RING finger protein 145 OS=Xenopu...490.81     36.6     33     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
219Q7T308    474   RN168_DANRE E3 ubiquitin-protein ligase RNF16...340.84     36.2     41     59GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
220Q9QZS2    194   RNF4_MOUSE E3 ubiquitin-protein ligase RNF4 O...270.87     35.4     44     67GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0031491; F:nucleosome binding; ISS:UniProtKB.::GO:0032184; F:SUMO polymer binding; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0090234; P:regulation of kinetochore assembly; ISS:UniProtKB.::GO:0090169; P:regulation of spindle assembly; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
221Q8LBA0    223   NIPL2_ARATH NEP1-interacting protein-like 2 O...480.89     35.4     33     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0010200; P:response to chitin; IEP:TAIR.
222Q5BIY5    695   RN145_XENLA RING finger protein 145 OS=Xenopu...330.98     36.2     36     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
223Q8RXD4    941   BRCA1_ARATH Protein BREAST CANCER SUSCEPTIBIL...340.99     36.2     35     62GO:0005634; C:nucleus; IEA:InterPro.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006310; P:DNA recombination; IMP:TAIR.::GO:0006281; P:DNA repair; IMP:TAIR.::GO:0010332; P:response to gamma radiation; IEP:TAIR.
224Q9ZU51    147   RHA2B_ARATH Probable E3 ubiquitin-protein lig...281     34.7     46     68
GO:0004842; F:ubiquitin-protein ligase activity; TAS:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0080167; P:response to karrikin; IEP:TAIR.
225Q803C1    485   RNF8_DANRE E3 ubiquitin-protein ligase RNF8 O...651     36.2     31     49GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:InterPro.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
226Q7TPV2    1204   DZIP3_MOUSE E3 ubiquitin-protein ligase DZIP3...291     36.2     41     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
227O88846    194   RNF4_RAT E3 ubiquitin-protein ligase RNF4 OS=...271     35     44     67GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; IPI:RGD.::GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0030331; F:estrogen receptor binding; IDA:RGD.::GO:0031491; F:nucleosome binding; IDA:UniProtKB.::GO:0033142; F:progesterone receptor binding; IPI:RGD.::GO:0032184; F:SUMO polymer binding; IPI:UniProtKB.::GO:0017025; F:TBP-class protein binding; TAS:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; IMP:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0090234; P:regulation of kinetochore assembly; ISS:UniProtKB.::GO:0090169; P:regulation of spindle assembly; ISS:UniProtKB.::GO:0046685; P:response to arsenic-containing substance; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
228Q6ZMN7    1036   PZRN4_HUMAN PDZ domain-containing RING finger...271.1     36.2     41     56
GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
229E7FAP1    630   RN169_DANRE E3 ubiquitin-protein ligase RNF16...611.1     36.2     30     49
GO:0008270; F:zinc ion binding; IEA:InterPro.
230Q75DC2    328   ASR1_ASHGO Alcohol-sensitive RING finger prot...361.1     35.8     44     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
231Q86Y13    1208   DZIP3_HUMAN E3 ubiquitin-protein ligase DZIP3...291.1     36.2     41     55GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0019902; F:phosphatase binding; IDA:UniProtKB.::GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.::GO:0003723; F:RNA binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.
232P78317    190   RNF4_HUMAN E3 ubiquitin-protein ligase RNF4 O...271.1     35     44     67GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0003677; F:DNA binding; ISS:UniProtKB.::GO:0031491; F:nucleosome binding; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0032184; F:SUMO polymer binding; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0090234; P:regulation of kinetochore assembly; IMP:UniProtKB.::GO:0090169; P:regulation of spindle assembly; IMP:UniProtKB.::GO:0046685; P:response to arsenic-containing substance; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
233Q9UTL9    1375   YIV5_SCHPO Uncharacterized ATP-dependent heli...271.1     36.2     37     67GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; ISS:PomBase.
234Q5C8U3    515   TRIM5_CERTA Tripartite motif-containing prote...361.1     35.8     50     61GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
235O22255    227   ATL64_ARATH RING-H2 finger protein ATL64 OS=A...271.1     35.4     48     63GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
236Q6PJ69    517   TRI65_HUMAN Tripartite motif-containing prote...411.1     35.8     39     54GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
237P93030    193   RMA2_ARATH E3 ubiquitin-protein ligase RMA2 O...691.1     35     28     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:TAIR.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
238P09309    467   IE61_VZVD E3 ubiquitin-protein ligase IE61 OS...611.1     35.8     30     41
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
239Q9EPZ8    682   RN103_RAT E3 ubiquitin-protein ligase RNF103 ...281.2     35.8     46     64GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
240Q9R1W3    683   RN103_MOUSE E3 ubiquitin-protein ligase RNF10...281.2     35.8     46     64GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
241Q587N7    515   TRIM5_CHLAE Tripartite motif-containing prote...361.2     35.8     50     61GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
records
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