Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR143C
Length:
610
Number of sequences:
5887
Description:
YDR143C SAN1 SGDID:S000002550, Chr IV from 743874-742042, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-protein ligase; involved in the proteasome-dependent degradation of aberrant nuclear proteins; targets substrates with regions of exposed hydrophobicity containing 5 or more contiguous hydrophobic residues; contains intrinsically disordered regions that contribute to substrate recognition"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q9V8P9    1038   TOPRS_DROME E3 ubiquitin-protein ligase Topor...250.11     39.3     44     72GO:0005652; C:nuclear lamina; IDA:UniProtKB.::GO:0005700; C:polytene chromosome; IDA:UniProtKB.
GO:0005521; F:lamin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0006997; P:nucleus organization; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IGI:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
152Q6BLM3    491   RAD18_DEBHA Postreplication repair E3 ubiquit...1070.11     38.9     22     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
153Q9D304    428   RN128_MOUSE E3 ubiquitin-protein ligase RNF12...360.12     38.9     33     61GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005770; C:late endosome; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042036; P:negative regulation of cytokine biosynthetic process; IDA:MGI.
154Q4V7B8    350   RNF44_RAT RING finger protein 44 OS=Rattus no...310.12     38.9     45     61
GO:0008270; F:zinc ion binding; IEA:InterPro.
155Q5SSZ7    913   ZNRF3_MOUSE Zinc/RING finger protein 3 OS=Mus...830.12     39.3     27     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
156Q5RF74    428   RN128_PONAB E3 ubiquitin-protein ligase RNF12...360.13     38.9     33     61GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
157Q7L0R7    432   RNF44_HUMAN RING finger protein 44 OS=Homo sa...310.13     38.9     45     61
GO:0008270; F:zinc ion binding; IEA:InterPro.
158Q8TEB7    428   RN128_HUMAN E3 ubiquitin-protein ligase RNF12...360.13     38.9     33     61GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
159O43085    695   DSC1_SCHPO DSC E3 ubiquitin ligase complex su...250.13     38.9     40     68GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; ISS:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; ISS:PomBase.
160Q6NRG0    532   RNF8B_XENLA E3 ubiquitin-protein ligase RNF8-...1050.13     38.9     24     36GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:InterPro.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
161Q08CG8    448   RNF44_DANRE RING finger protein 44 OS=Danio r...310.14     38.5     45     61
GO:0008270; F:zinc ion binding; IEA:InterPro.
162Q3UHJ8    407   RNF44_MOUSE RING finger protein 44 OS=Mus mus...310.14     38.5     45     61
GO:0008270; F:zinc ion binding; IEA:InterPro.
163Q8LDB8    381   RING2_ARATH E3 ubiquitin-protein ligase At1g6...330.14     38.5     45     64GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
164Q9NS56    1045   TOPRS_HUMAN E3 ubiquitin-protein ligase Topor...1300.15     38.9     27     42GO:0016607; C:nuclear speck; IDA:UniProtKB.::GO:0016605; C:PML body; IDA:UniProtKB.
GO:0003823; F:antigen binding; IPI:UniProtKB.::GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0044547; F:DNA topoisomerase binding; IPI:UniProtKB.::GO:0019789; F:SUMO ligase activity; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IDA:UniProtKB.::GO:0051457; P:maintenance of protein location in nucleus; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0016925; P:protein sumoylation; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; NAS:UniProtKB.
165P36096    758   TUL1_YEAST Transmembrane E3 ubiquitin-protein...380.16     38.9     37     55GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:SGD.
166Q8BI21    518   RNF38_MOUSE RING finger protein 38 OS=Mus mus...310.19     38.5     45     61
GO:0008270; F:zinc ion binding; IEA:InterPro.
167Q5A4N5    378   RAD18_CANAL Postreplication repair E3 ubiquit...410.2     38.1     34     66GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
168Q29RU0    431   RN128_BOVIN E3 ubiquitin-protein ligase RNF12...360.2     38.1     31     61GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
169P10862    487   RAD18_YEAST Postreplication repair E3 ubiquit...690.2     38.1     33     43GO:0000790; C:nuclear chromatin; IDA:SGD.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003697; F:single-stranded DNA binding; IDA:SGD.::GO:0004842; F:ubiquitin-protein ligase activity; IPI:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042275; P:error-free postreplication DNA repair; IGI:SGD.::GO:0070987; P:error-free translesion synthesis; IGI:SGD.::GO:0042276; P:error-prone translesion synthesis; IGI:SGD.::GO:0006513; P:protein monoubiquitination; IMP:SGD.
170O64425    249   RMA1_ARATH E3 ubiquitin-protein ligase RMA1 O...490.2     37.7     33     51GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032527; P:protein exit from endoplasmic reticulum; IMP:TAIR.::GO:0032940; P:secretion by cell; IGI:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
171Q9SN27    225   ATL59_ARATH E3 ubiquitin-protein ligase ATL59...510.22     37.4     33     43GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
172Q6FPI4    411   RAD18_CANGA Postreplication repair E3 ubiquit...690.23     38.1     28     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
173Q8RXX9    398   ATL6_ARATH E3 ubiquitin-protein ligase ATL6 O...550.24     37.7     31     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0010200; P:response to chitin; IEP:TAIR.
174Q80Z37    1033   TOPRS_MOUSE E3 ubiquitin-protein ligase Topor...1130.25     38.1     27     42GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0016605; C:PML body; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:MGI.::GO:0019789; F:SUMO ligase activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IDA:MGI.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IGI:MGI.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016925; P:protein sumoylation; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IDA:MGI.
175Q9SN28    236   ATL7_ARATH RING-H2 finger protein ATL7 OS=Ara...270.26     37.4     48     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
176Q7ZUK0    364   RN146_DANRE E3 ubiquitin-protein ligase rnf14...340.26     37.7     41     59GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
177Q8W571    323   ATL32_ARATH RING-H2 finger protein ATL32 OS=A...900.27     37.7     29     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
178Q9DBU5    667   RNF6_MOUSE E3 ubiquitin-protein ligase RNF6 O...320.28     37.7     41     59GO:0030424; C:axon; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0016605; C:PML body; IDA:MGI.
GO:0050681; F:androgen receptor binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IDA:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030517; P:negative regulation of axon extension; IMP:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0044314; P:protein K27-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IMP:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:MGI.
179Q9SJJ7    237   ATL57_ARATH RING-H2 finger protein ATL57 OS=A...650.28     37     35     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
180Q84W40    404   ATL11_ARATH RING-H2 finger protein ATL11 OS=A...500.28     37.7     34     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
181Q8AWW4    404   RN128_XENLA E3 ubiquitin-protein ligase RNF12...430.3     37.7     33     53GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
records
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