Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR143C
Length:
610
Number of sequences:
5887
Description:
YDR143C SAN1 SGDID:S000002550, Chr IV from 743874-742042, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-protein ligase; involved in the proteasome-dependent degradation of aberrant nuclear proteins; targets substrates with regions of exposed hydrophobicity containing 5 or more contiguous hydrophobic residues; contains intrinsically disordered regions that contribute to substrate recognition"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q5SPX3    379   RN215_MOUSE RING finger protein 215 OS=Mus mu...260.065     39.7     50     69GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
122Q5XHH7    595   SYVNB_XENLA E3 ubiquitin-protein ligase synov...300.068     39.7     40     60GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
123Q1L5Z9    754   LONF2_HUMAN LON peptidase N-terminal domain a...970.069     40     27     41
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
124Q9M0R7    132   ATL39_ARATH RING-H2 finger protein ATL39 OS=A...710.07     37.7     32     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
125Q9Y6U7    377   RN215_HUMAN RING finger protein 215 OS=Homo s...260.07     39.7     50     69GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
126Q0V9R0    954   RN111_XENTR E3 ubiquitin-protein ligase arkad...300.07     40     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
127Q6NRV8    959   R111B_XENLA E3 ubiquitin-protein ligase arkad...300.07     40     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
128Q8L9T5    304   ATL2_ARATH RING-H2 finger protein ATL2 OS=Ara...450.072     39.3     33     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006952; P:defense response; IDA:TAIR.::GO:0010200; P:response to chitin; IEP:TAIR.
129Q6NRL6    605   SYVNA_XENLA E3 ubiquitin-protein ligase synov...300.072     39.7     40     60GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
130Q9UPQ7    1066   PZRN3_HUMAN E3 ubiquitin-protein ligase PDZRN...340.072     40     44     59
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
131Q8HXH0    718   LONF3_MACFA LON peptidase N-terminal domain a...518.6     33.1     33     49
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
132Q66J97    967   R111C_XENLA E3 ubiquitin-protein ligase arkad...300.072     40     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
133Q90ZT7    923   R111A_XENLA E3 ubiquitin-protein ligase arkad...300.073     40     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
134C0HBT3    349   RN146_SALSA E3 ubiquitin-protein ligase rnf14...580.075     39.3     34     50GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0072572; F:poly-ADP-D-ribose binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
135Q69ZS0    1063   PZRN3_MOUSE E3 ubiquitin-protein ligase PDZRN...340.075     40     44     59GO:0031594; C:neuromuscular junction; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007528; P:neuromuscular junction development; IMP:UniProtKB.
136Q8LF65    235   ATL17_ARATH RING-H2 finger protein ATL17 OS=A...470.077     38.9     38     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006952; P:defense response; IEA:UniProtKB-KW.::GO:0010200; P:response to chitin; IEP:TAIR.
137Q8RX29    217   ATL70_ARATH RING-H2 finger protein ATL70 OS=A...330.077     38.9     48     64GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
138Q99ML9    989   RN111_MOUSE E3 ubiquitin-protein ligase Arkad...300.078     39.7     40     60GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0043234; C:protein complex; IDA:MGI.
GO:0004842; F:ubiquitin-protein ligase activity; IMP:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007389; P:pattern specification process; IMP:MGI.::GO:0031398; P:positive regulation of protein ubiquitination; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:MGI.::GO:0000209; P:protein polyubiquitination; IMP:BHF-UCL.::GO:0030579; P:ubiquitin-dependent SMAD protein catabolic process; IMP:BHF-UCL.
139Q5R476    986   RN111_PONAB E3 ubiquitin-protein ligase Arkad...300.082     39.7     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
140Q7ZX20    540   RNF8A_XENLA E3 ubiquitin-protein ligase RNF8-...310.083     39.7     42     58GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:InterPro.::GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0033522; P:histone H2A ubiquitination; ISS:UniProtKB.::GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
141Q6ZNA4    994   RN111_HUMAN E3 ubiquitin-protein ligase Arkad...300.084     39.7     40     60GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:BHF-UCL.
142Q8GUU2    359   RIE1_ARATH E3 ubiquitin protein ligase RIE1 O...290.085     39.3     48     62GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009790; P:embryo development; IMP:UniProtKB.
143Q9H0F5    515   RNF38_HUMAN RING finger protein 38 OS=Homo sa...310.091     39.3     45     61
GO:0008270; F:zinc ion binding; IEA:InterPro.
144P68907    1062   PZRN3_RAT E3 ubiquitin-protein ligase PDZRN3 ...340.094     39.7     44     59
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
145Q95K04    376   RN133_MACFA E3 ubiquitin-protein ligase RNF13...700.095     39.3     31     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
146Q86TM6    617   SYVN1_HUMAN E3 ubiquitin-protein ligase synov...300.095     39.3     40     60GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:HPA.
GO:0016881; F:acid-amino acid ligase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006987; P:activation of signaling protein activity involved in unfolded protein response; TAS:Reactome.::GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.
147Q9LN71    408   RING1_ARATH E3 ubiquitin-protein ligase At1g1...330.096     39.3     45     64GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
148Q496Y0    759   LONF3_HUMAN LON peptidase N-terminal domain a...950.099     39.3     24     44
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
149Q9DBY1    612   SYVN1_MOUSE E3 ubiquitin-protein ligase synov...300.1     39.3     40     60GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.
150Q9Y252    685   RNF6_HUMAN E3 ubiquitin-protein ligase RNF6 O...300.1     39.3     43     60GO:0030424; C:axon; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030517; P:negative regulation of axon extension; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0044314; P:protein K27-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0060765; P:regulation of androgen receptor signaling pathway; IMP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
151Q9V8P9    1038   TOPRS_DROME E3 ubiquitin-protein ligase Topor...250.11     39.3     44     72GO:0005652; C:nuclear lamina; IDA:UniProtKB.::GO:0005700; C:polytene chromosome; IDA:UniProtKB.
GO:0005521; F:lamin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007095; P:mitotic cell cycle G2/M transition DNA damage checkpoint; IGI:FlyBase.::GO:0006997; P:nucleus organization; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IGI:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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