Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR139C
Length:
77
Number of sequences:
5887
Description:
YDR139C RUB1 SGDID:S000002546, Chr IV from 733702-733618,733924-733776, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-like protein with similarity to mammalian NEDD8; conjugation (neddylation) substrates include the cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2 enzyme)"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211Q15459    793   SF3A1_HUMAN Splicing factor 3A subunit 1 OS=H...690.038     35     32     52GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005684; C:U2-type spliceosomal complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IDA:UniProtKB.
GO:0000389; P:nuclear mRNA 3'-splice site recognition; TAS:HGNC.
212A2VDN6    793   SF3A1_BOVIN Splicing factor 3A subunit 1 OS=B...690.038     35     32     52GO:0005684; C:U2-type spliceosomal complex; ISS:UniProtKB.
GO:0003723; F:RNA binding; ISS:UniProtKB.
GO:0000398; P:nuclear mRNA splicing, via spliceosome; ISS:UniProtKB.
213Q9YHD3    1135   BAG6A_XENLA Large proline-rich protein bag6-A...720.045     35     36     51GO:0071818; C:BAT3 complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0070628; F:proteasome binding; ISS:UniProtKB.::GO:0043022; F:ribosome binding; ISS:UniProtKB.
GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0007420; P:brain development; ISS:UniProtKB.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0018393; P:internal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0001822; P:kidney development; ISS:UniProtKB.::GO:0030324; P:lung development; ISS:UniProtKB.::GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.::GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; ISS:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
214Q15646    514   OASL_HUMAN 59 kDa 2'-5'-oligoadenylate syntha...520.061     34.3     31     58GO:0005829; C:cytosol; TAS:Reactome.::GO:0005730; C:nucleolus; TAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0003677; F:DNA binding; TAS:UniProtKB.::GO:0003725; F:double-stranded RNA binding; TAS:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; TAS:UniProtKB.::GO:0016740; F:transferase activity; IEA:InterPro.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.
215Q10169    354   DSK2_SCHPO Deubiquitination-protection protei...710.08     33.9     25     51GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0031593; F:polyubiquitin binding; IDA:PomBase.
GO:0033554; P:cellular response to stress; NAS:PomBase.::GO:0030433; P:ER-associated protein catabolic process; ISS:PomBase.::GO:0042177; P:negative regulation of protein catabolic process; IMP:PomBase.::GO:0030474; P:spindle pole body duplication; ISS:PomBase.
216Q54LV1    342   RAD23_DICDI UV excision repair protein RAD23 ...640.11     33.5     38     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0003684; F:damaged DNA binding; IEA:InterPro.
GO:0006289; P:nucleotide-excision repair; IEA:InterPro.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IEA:InterPro.
217P34675    1620   YO25_CAEEL Uncharacterized protein ZK688.5 OS...680.11     33.9     29     51
GO:0007165; P:signal transduction; IEA:InterPro.
218P05161    165   ISG15_HUMAN Ubiquitin-like protein ISG15 OS=H...730.14     32.7     27     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005615; C:extracellular space; NAS:UniProtKB.
GO:0007267; P:cell-cell signaling; NAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032020; P:ISG15-protein conjugation; IDA:HGNC.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.
219Q96T88    793   UHRF1_HUMAN E3 ubiquitin-protein ligase UHRF1...600.16     33.1     28     55GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008327; F:methyl-CpG binding; IDA:UniProtKB.::GO:0035064; F:methylated histone residue binding; IDA:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; IEP:BHF-UCL.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0032270; P:positive regulation of cellular protein metabolic process; IDA:BHF-UCL.::GO:2000373; P:positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity; IC:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IC:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
220Q6MG49    1146   BAG6_RAT Large proline-rich protein BAG6 OS=R...680.2     32.7     34     50GO:0071818; C:BAT3 complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0070628; F:proteasome binding; ISS:UniProtKB.::GO:0043022; F:ribosome binding; ISS:UniProtKB.
GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0007420; P:brain development; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0018393; P:internal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0001822; P:kidney development; ISS:UniProtKB.::GO:0030324; P:lung development; ISS:UniProtKB.::GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IEP:RGD.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.::GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; ISS:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
221Q2USD7    402   DDI1_ASPOR DNA damage-inducible protein 1 OS=...500.22     32.7     32     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004190; F:aspartic-type endopeptidase activity; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006508; P:proteolysis; IEA:InterPro.
222Q29RK4    408   RD23B_BOVIN UV excision repair protein RAD23 ...660.23     32.7     27     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.::GO:0071942; C:XPC complex; ISS:UniProtKB.
GO:0003684; F:damaged DNA binding; IEA:InterPro.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IEA:InterPro.
223O84192    836   GYRA_CHLTR DNA gyrase subunit A OS=Chlamydia ...560.34     32.3     30     61GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
224Q9H347    655   UBQL3_HUMAN Ubiquilin-3 OS=Homo sapiens (Huma...690.36     32     29     52
225Q7SZR5    100   SUMO1_DANRE Small ubiquitin-related modifier ...440.4     30.8     32     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
226Q6GL38    240   UBTD1_XENTR Ubiquitin domain-containing prote...430.45     31.6     35     53
227Q8C5U9    658   UBQL3_MOUSE Ubiquilin-3 OS=Mus musculus (Mous...720.55     31.6     28     53
228P54727    409   RD23B_HUMAN UV excision repair protein RAD23 ...660.61     31.2     27     55GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.::GO:0071942; C:XPC complex; IDA:UniProtKB.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.::GO:0003697; F:single-stranded DNA binding; TAS:ProtInc.
GO:0000715; P:nucleotide-excision repair, DNA damage recognition; IDA:UniProtKB.::GO:0000718; P:nucleotide-excision repair, DNA damage removal; TAS:Reactome.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IEA:InterPro.::GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
229P63072    162   UBD_MOUSE Ubiquitin D OS=Mus musculus (Mouse)...620.63     30.8     26     50GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0070628; F:proteasome binding; ISS:UniProtKB.
GO:0070842; P:aggresome assembly; ISS:UniProtKB.::GO:0043011; P:myeloid dendritic cell differentiation; ISS:UniProtKB.::GO:0035417; P:negative regulation of mitotic prometaphase; ISS:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0016567; P:protein ubiquitination; IMP:UniProtKB.::GO:0034341; P:response to interferon-gamma; IEP:UniProtKB.::GO:0034612; P:response to tumor necrosis factor; IEP:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
230P46379    1132   BAG6_HUMAN Large proline-rich protein BAG6 OS...680.71     31.2     32     50GO:0071818; C:BAT3 complex; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0070628; F:proteasome binding; ISS:UniProtKB.::GO:0043022; F:ribosome binding; IDA:UniProtKB.
GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0007420; P:brain development; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IMP:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0018393; P:internal peptidyl-lysine acetylation; IDA:UniProtKB.::GO:0001822; P:kidney development; ISS:UniProtKB.::GO:0030324; P:lung development; ISS:UniProtKB.::GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.::GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; IDA:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
231Q9PKK4    833   GYRA_CHLMU DNA gyrase subunit A OS=Chlamydia ...560.72     31.2     30     61GO:0005694; C:chromosome; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003918; F:DNA topoisomerase (ATP-hydrolyzing) activity; IEA:EC.
GO:0006265; P:DNA topological change; IEA:InterPro.
232P32628    398   RAD23_YEAST UV excision repair protein RAD23 ...670.72     31.2     25     54GO:0005739; C:mitochondrion; IDA:SGD.::GO:0000111; C:nucleotide-excision repair factor 2 complex; IDA:SGD.::GO:0000502; C:proteasome complex; IMP:SGD.
GO:0003684; F:damaged DNA binding; IDA:SGD.::GO:0030674; F:protein binding, bridging; IPI:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.
GO:0030433; P:ER-associated protein catabolic process; IMP:SGD.::GO:0000715; P:nucleotide-excision repair, DNA damage recognition; TAS:SGD.::GO:0006517; P:protein deglycosylation; IDA:SGD.
233Q5R684    589   UBQL1_PONAB Ubiquilin-1 OS=Pongo abelii (Suma...710.73     31.2     32     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0005488; F:binding; IEA:InterPro.
234Q9QZM0    638   UBQL2_MOUSE Ubiquilin-2 OS=Mus musculus (Mous...710.75     31.2     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.
235Q9Z1R2    1154   BAG6_MOUSE Large proline-rich protein BAG6 OS...680.75     31.2     32     50GO:0071818; C:BAT3 complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0030544; F:Hsp70 protein binding; IPI:UniProtKB.::GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.::GO:0070628; F:proteasome binding; IDA:UniProtKB.::GO:0043022; F:ribosome binding; ISS:UniProtKB.
GO:0002474; P:antigen processing and presentation of peptide antigen via MHC class I; TAS:UniProtKB.::GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; IMP:UniProtKB.::GO:0007420; P:brain development; IMP:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0009790; P:embryo development; IMP:UniProtKB.::GO:0018393; P:internal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0001822; P:kidney development; IMP:UniProtKB.::GO:0030324; P:lung development; IMP:UniProtKB.::GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0050821; P:protein stabilization; IMP:UniProtKB.::GO:0007283; P:spermatogenesis; IMP:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; IMP:UniProtKB.::GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; ISS:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
236Q9UMX0    589   UBQL1_HUMAN Ubiquilin-1 OS=Homo sapiens (Huma...710.77     31.2     32     52GO:0005783; C:endoplasmic reticulum; IDA:HGNC.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; NAS:UniProtKB.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0019900; F:kinase binding; IPI:UniProtKB.
GO:0006915; P:apoptotic process; IMP:HGNC.::GO:0031396; P:regulation of protein ubiquitination; IDA:HGNC.::GO:0001666; P:response to hypoxia; IMP:HGNC.
237Q9UHD9    624   UBQL2_HUMAN Ubiquilin-2 OS=Homo sapiens (Huma...710.83     30.8     31     51GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0008219; P:cell death; IEA:UniProtKB-KW.
238A5D9M6    1128   BAG6_PIG Large proline-rich protein BAG6 OS=S...680.87     30.8     32     50GO:0071818; C:BAT3 complex; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0031593; F:polyubiquitin binding; ISS:UniProtKB.::GO:0070628; F:proteasome binding; ISS:UniProtKB.::GO:0043022; F:ribosome binding; ISS:UniProtKB.
GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0007420; P:brain development; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; ISS:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0018393; P:internal peptidyl-lysine acetylation; ISS:UniProtKB.::GO:0001822; P:kidney development; ISS:UniProtKB.::GO:0030324; P:lung development; ISS:UniProtKB.::GO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0007130; P:synaptonemal complex assembly; ISS:UniProtKB.::GO:0071816; P:tail-anchored membrane protein insertion into ER membrane; ISS:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
239Q9JJP9    582   UBQL1_RAT Ubiquilin-1 OS=Rattus norvegicus (R...710.88     30.8     32     52GO:0005783; C:endoplasmic reticulum; ISS:HGNC.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:HGNC.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0019904; F:protein domain specific binding; IPI:RGD.
GO:0006915; P:apoptotic process; ISS:HGNC.::GO:0031396; P:regulation of protein ubiquitination; ISS:HGNC.::GO:0001666; P:response to hypoxia; ISS:HGNC.
240P54725    363   RD23A_HUMAN UV excision repair protein RAD23 ...640.93     30.8     27     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0031593; F:polyubiquitin binding; IDA:UniProtKB.::GO:0003697; F:single-stranded DNA binding; TAS:ProtInc.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006289; P:nucleotide-excision repair; IDA:UniProtKB.::GO:0045070; P:positive regulation of viral genome replication; IMP:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IEA:InterPro.::GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.
241Q8R317    582   UBQL1_MOUSE Ubiquilin-1 OS=Mus musculus (Mous...710.99     30.8     32     52GO:0005783; C:endoplasmic reticulum; ISS:HGNC.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:HGNC.::GO:0000502; C:proteasome complex; IEA:UniProtKB-KW.
GO:0019215; F:intermediate filament binding; NAS:UniProtKB.::GO:0019900; F:kinase binding; ISS:UniProtKB.::GO:0005102; F:receptor binding; NAS:UniProtKB.
GO:0006915; P:apoptotic process; ISS:HGNC.::GO:0031396; P:regulation of protein ubiquitination; ISS:HGNC.::GO:0001666; P:response to hypoxia; ISS:HGNC.
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