Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR135C
Length:
1515
Number of sequences:
5887
Description:
YDR135C YCF1 SGDID:S000002542, Chr IV from 727551-723004, Genome Release 64-1-1, reverse complement, Verified ORF, "Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P39109    1515   YCFI_YEAST Metal resistance protein YCF1 OS=S...15150     3128     100     100GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015127; F:bilirubin transmembrane transporter activity; IMP:SGD.::GO:0015431; F:glutathione S-conjugate-exporting ATPase activity; IDA:SGD.
GO:0046686; P:response to cadmium ion; IEA:UniProtKB-KW.
2Q10185    1478   ABC2_SCHPO ATP-binding cassette transporter a...14920     1229     45     63GO:0000329; C:fungal-type vacuole membrane; IDA:PomBase.::GO:0005794; C:Golgi apparatus; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0071997; F:glutathione S-conjugate-transporting ATPase activity; IMP:PomBase.::GO:0071992; F:phytochelatin transmembrane transporter activity; IMP:PomBase.
GO:0071276; P:cellular response to cadmium ion; IGI:PomBase.::GO:0071996; P:glutathione import into vacuole; IMP:PomBase.::GO:0071995; P:phytochelatin import into vacuole; IMP:PomBase.::GO:0009636; P:response to toxin; IEA:UniProtKB-KW.
3Q9P5N0    1465   ABC3_SCHPO ATP-binding cassette transporter a...14560     1142     43     61GO:0000329; C:fungal-type vacuole membrane; IDA:PomBase.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IMP:PomBase.
4Q5F364    1525   MRP1_CHICK Multidrug resistance-associated pr...15540     1092     41     60GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
5Q864R9    1531   MRP1_MACFA Multidrug resistance-associated pr...14700     1087     41     61GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
6P33527    1531   MRP1_HUMAN Multidrug resistance-associated pr...14700     1085     42     61GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; TAS:ProtInc.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; TAS:ProtInc.
GO:0019370; P:leukotriene biosynthetic process; TAS:Reactome.::GO:0006692; P:prostanoid metabolic process; TAS:Reactome.::GO:0042493; P:response to drug; TAS:ProtInc.
7P14772    1559   BPT1_YEAST Bile pigment transporter 1 OS=Sacc...15950     1083     41     59GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.::GO:0015127; F:bilirubin transmembrane transporter activity; IGI:SGD.::GO:0015086; F:cadmium ion transmembrane transporter activity; IDA:SGD.
8O35379    1528   MRP1_MOUSE Multidrug resistance-associated pr...14740     1069     41     61GO:0005887; C:integral to plasma membrane; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
9Q8HXQ5    1530   MRP1_BOVIN Multidrug resistance-associated pr...14630     1068     41     61GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
10Q6UR05    1531   MRP1_CANFA Multidrug resistance-associated pr...14690     1065     41     60GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
11Q8CG09    1532   MRP1_RAT Multidrug resistance-associated prot...14730     1051     41     60GO:0016323; C:basolateral plasma membrane; IDA:RGD.::GO:0005737; C:cytoplasm; IDA:RGD.::GO:0005887; C:integral to plasma membrane; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015562; F:efflux transmembrane transporter activity; IDA:RGD.::GO:0015431; F:glutathione S-conjugate-exporting ATPase activity; IMP:RGD.::GO:0034634; F:glutathione transmembrane transporter activity; IMP:RGD.::GO:0034040; F:lipid-transporting ATPase activity; IDA:RGD.::GO:0005324; F:long-chain fatty acid transporter activity; IDA:RGD.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0046624; F:sphingolipid transporter activity; IMP:RGD.::GO:0008559; F:xenobiotic-transporting ATPase activity; IDA:RGD.
GO:0060326; P:cell chemotaxis; IMP:RGD.::GO:0043215; P:daunorubicin transport; IMP:RGD.::GO:0046618; P:drug export; IDA:RGD.::GO:0043526; P:neuroprotection; IMP:RGD.::GO:0033700; P:phospholipid efflux; IMP:RGD.::GO:0015911; P:plasma membrane long-chain fatty acid transport; IDA:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0006979; P:response to oxidative stress; IMP:RGD.
12B2RX12    1523   MRP3_MOUSE Canalicular multispecific organic ...14540     1050     40     60GO:0005887; C:integral to plasma membrane; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
13Q63120    1541   MRP2_RAT Canalicular multispecific organic an...15900     1027     38     57GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.::GO:0008514; F:organic anion transmembrane transporter activity; TAS:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD.
GO:0030644; P:cellular chloride ion homeostasis; IDA:RGD.::GO:0006855; P:drug transmembrane transport; IMP:RGD.::GO:0015732; P:prostaglandin transport; IMP:RGD.::GO:0046685; P:response to arsenic-containing substance; IEP:RGD.::GO:0009408; P:response to heat; IEP:RGD.::GO:0031427; P:response to methotrexate; IEP:RGD.::GO:0006979; P:response to oxidative stress; IEP:RGD.::GO:0070327; P:thyroid hormone transport; IMP:RGD.
14Q28689    1564   MRP2_RABIT Canalicular multispecific organic ...15950     1018     38     56GO:0016324; C:apical plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
15O15438    1527   MRP3_HUMAN Canalicular multispecific organic ...14540     1013     39     59GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.
GO:0005524; F:ATP binding; TAS:ProtInc.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; TAS:ProtInc.::GO:0008514; F:organic anion transmembrane transporter activity; TAS:ProtInc.
GO:0015721; P:bile acid and bile salt transport; TAS:Reactome.::GO:0008206; P:bile acid metabolic process; TAS:Reactome.
16O88563    1522   MRP3_RAT Canalicular multispecific organic an...14350     1013     39     60GO:0016323; C:basolateral plasma membrane; IDA:RGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015432; F:bile acid-exporting ATPase activity; IMP:RGD.::GO:0008559; F:xenobiotic-transporting ATPase activity; IMP:RGD.
GO:0015722; P:canalicular bile acid transport; IDA:MGI.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0032496; P:response to lipopolysaccharide; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0010243; P:response to organic nitrogen; IEP:RGD.
17Q92887    1545   MRP2_HUMAN Canalicular multispecific organic ...13790     995     41     59GO:0016324; C:apical plasma membrane; ISS:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; TAS:ProtInc.::GO:0008514; F:organic anion transmembrane transporter activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.
18Q8VI47    1543   MRP2_MOUSE Canalicular multispecific organic ...16030     981     38     56GO:0016324; C:apical plasma membrane; IDA:MGI.::GO:0005887; C:integral to plasma membrane; IDA:MGI.::GO:0046581; C:intercellular canaliculus; IDA:MGI.::GO:0005624; C:membrane fraction; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
19O15439    1325   MRP4_HUMAN Multidrug resistance-associated pr...13260     845     38     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0031088; C:platelet dense granule membrane; IDA:MGI.
GO:0016404; F:15-hydroxyprostaglandin dehydrogenase (NAD+) activity; NAS:UniProtKB.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.::GO:0005254; F:chloride channel activity; IEA:InterPro.
GO:0030168; P:platelet activation; TAS:Reactome.::GO:0002576; P:platelet degranulation; TAS:Reactome.
20Q42093    1623   AB2C_ARATH ABC transporter C family member 2 ...13110     850     39     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000325; C:plant-type vacuole; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:EC.
21Q9C8G9    1622   AB1C_ARATH ABC transporter C family member 1 ...13130     849     39     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000325; C:plant-type vacuole; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0015446; F:arsenite-transmembrane transporting ATPase activity; IDA:TAIR.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0071992; F:phytochelatin transmembrane transporter activity; IDA:TAIR.::GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:EC.
GO:0046685; P:response to arsenic-containing substance; IMP:TAIR.
22Q9C8H1    1495   AB11C_ARATH ABC transporter C family member 1...13570     826     37     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:EC.
23Q54JR2    1412   ABCC3_DICDI ABC transporter C family member 3...13190     822     39     56GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; ISS:dictyBase.
24Q9C8H0    1495   AB12C_ARATH ABC transporter C family member 1...13190     822     38     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:EC.
25Q8ST87    1334   ABCCA_DICDI ABC transporter C family member 1...13190     816     37     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; ISS:dictyBase.
26O95255    1503   MRP6_HUMAN Multidrug resistance-associated pr...14920     810     36     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; TAS:ProtInc.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; TAS:ProtInc.
GO:0042493; P:response to drug; TAS:ProtInc.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
27Q7GB25    1514   AB5C_ARATH ABC transporter C family member 5 ...13210     787     36     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000325; C:plant-type vacuole; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008281; F:sulfonylurea receptor activity; IDA:TAIR.::GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:EC.
GO:0030007; P:cellular potassium ion homeostasis; IMP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR.
28Q9M1C7    1506   AB9C_ARATH ABC transporter C family member 9 ...13780     780     35     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:EC.
GO:0009624; P:response to nematode; IEP:TAIR.
29Q9LK64    1514   AB3C_ARATH ABC transporter C family member 3 ...13190     749     34     55GO:0048046; C:apoplast; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0000325; C:plant-type vacuole; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0010290; F:chlorophyll catabolite transmembrane transporter activity; IDA:TAIR.::GO:0015431; F:glutathione S-conjugate-exporting ATPase activity; IDA:TAIR.::GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:EC.
30Q9R1S7    1498   MRP6_MOUSE Multidrug resistance-associated pr...13440     744     36     53GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042626; F:ATPase activity, coupled to transmembrane movement of substances; IEA:InterPro.
31Q9LYS2    1453   AB10C_ARATH ABC transporter C family member 1...13090     743     34     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008559; F:xenobiotic-transporting ATPase activity; IEA:EC.
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