rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
631 | P18654 | 740 | KS6A3_MOUSE Ribosomal protein S6 kinase alpha... | 271 | 1e-25 | 117 | 28 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0032496; P:response to lipopolysaccharide; IMP:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0002224; P:toll-like receptor signaling pathway; IMP:UniProtKB. | 632 | P51812 | 740 | KS6A3_HUMAN Ribosomal protein S6 kinase alpha... | 271 | 1e-25 | 117 | 28 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045597; P:positive regulation of cell differentiation; TAS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; TAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043620; P:regulation of DNA-dependent transcription in response to stress; TAS:UniProtKB.::GO:0043555; P:regulation of translation in response to stress; TAS:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0001501; P:skeletal system development; TAS:ProtInc.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 633 | Q63531 | 735 | KS6A1_RAT Ribosomal protein S6 kinase alpha-1... | 344 | 1e-25 | 117 | 27 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004711; F:ribosomal protein S6 kinase activity; TAS:RGD.::GO:0008134; F:transcription factor binding; IDA:RGD. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:2000491; P:positive regulation of hepatic stellate cell activation; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:RGD. | 634 | Q9WUT3 | 733 | KS6A2_MOUSE Ribosomal protein S6 kinase alpha... | 289 | 1e-25 | 117 | 27 | 48 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005819; C:spindle; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004711; F:ribosomal protein S6 kinase activity; IDA:MGI. | | | | | | | | | | GO:0002035; P:brain renin-angiotensin system; IDA:MGI.::GO:0010659; P:cardiac muscle cell apoptotic process; IDA:MGI.::GO:0071322; P:cellular response to carbohydrate stimulus; IDA:MGI.::GO:0060047; P:heart contraction; IDA:MGI.::GO:0007507; P:heart development; IDA:MGI.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0000089; P:mitotic metaphase; IDA:MGI.::GO:0045786; P:negative regulation of cell cycle; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0001556; P:oocyte maturation; IDA:MGI.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:MGI.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0010628; P:positive regulation of gene expression; IDA:MGI.::GO:0070613; P:regulation of protein processing; IDA:MGI. | 635 | Q15349 | 733 | KS6A2_HUMAN Ribosomal protein S6 kinase alpha... | 289 | 1e-25 | 117 | 28 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 636 | O75385 | 1050 | ULK1_HUMAN Serine/threonine-protein kinase UL... | 248 | 1e-25 | 118 | 29 | 49 | GO:0005776; C:autophagic vacuole; IDA:UniProtKB.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB.::GO:0070969; C:ULK1-ATG13-FIP200 complex; IPI:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0032403; F:protein complex binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0010508; P:positive regulation of autophagy; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0008104; P:protein localization; IMP:UniProtKB. | 637 | Q64303 | 524 | PAK2_RAT Serine/threonine-protein kinase PAK ... | 231 | 1e-25 | 116 | 29 | 55 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 638 | Q8CIN4 | 524 | PAK2_MOUSE Serine/threonine-protein kinase PA... | 231 | 1e-25 | 116 | 29 | 55 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW. | 639 | Q5U2N4 | 459 | MKNK2_RAT MAP kinase-interacting serine/threo... | 277 | 1e-25 | 115 | 33 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 640 | Q90XF2 | 588 | KPCI_DANRE Protein kinase C iota type OS=Dani... | 283 | 1e-25 | 117 | 28 | 49 | GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031226; C:intrinsic to plasma membrane; IDA:ZFIN.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0005915; C:zonula adherens; IDA:ZFIN. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; ISS:UniProtKB.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0034334; P:adherens junction maintenance; IMP:ZFIN.::GO:0045217; P:cell-cell junction maintenance; IMP:ZFIN.::GO:0007502; P:digestive tract mesoderm development; IMP:ZFIN.::GO:0048546; P:digestive tract morphogenesis; IMP:ZFIN.::GO:0021744; P:dorsal motor nucleus of vagus nerve development; IMP:ZFIN.::GO:0035050; P:embryonic heart tube development; IMP:ZFIN.::GO:0000132; P:establishment of mitotic spindle orientation; IMP:ZFIN.::GO:0016332; P:establishment or maintenance of polarity of embryonic epithelium; IMP:ZFIN.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0045199; P:maintenance of epithelial cell apical/basal polarity; IMP:ZFIN.::GO:0008078; P:mesodermal cell migration; IMP:ZFIN.::GO:0001738; P:morphogenesis of a polarized epithelium; IMP:ZFIN.::GO:0001841; P:neural tube formation; IGI:ZFIN.::GO:0007405; P:neuroblast proliferation; IMP:ZFIN.::GO:0007097; P:nuclear migration; IMP:ZFIN.::GO:0042476; P:odontogenesis; IMP:ZFIN.::GO:0060042; P:retina morphogenesis in camera-type eye; IMP:ZFIN. | 641 | Q9QY01 | 1037 | ULK2_MOUSE Serine/threonine-protein kinase UL... | 240 | 1e-25 | 118 | 32 | 50 | GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0048675; P:axon extension; IMP:MGI.::GO:0048671; P:negative regulation of collateral sprouting; IMP:MGI.::GO:0010506; P:regulation of autophagy; IMP:UniProtKB.::GO:0042594; P:response to starvation; IDA:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro. | 642 | A8XNJ6 | 464 | SGK1_CAEBR Serine/threonine-protein kinase sg... | 269 | 1e-25 | 115 | 28 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007154; P:cell communication; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006950; P:response to stress; IEA:UniProtKB-KW. | 643 | Q29502 | 524 | PAK2_RABIT Serine/threonine-protein kinase PA... | 231 | 1e-25 | 115 | 29 | 55 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0097194; P:execution phase of apoptosis; IMP:UniProtKB.::GO:0043065; P:positive regulation of apoptotic process; IMP:UniProtKB. | 644 | O70405 | 1051 | ULK1_MOUSE Serine/threonine-protein kinase UL... | 242 | 1e-25 | 118 | 29 | 49 | GO:0030659; C:cytoplasmic vesicle membrane; IDA:MGI.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:MGI.::GO:0043005; C:neuron projection; IDA:MGI.::GO:0043025; C:neuronal cell body; IDA:MGI.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB.::GO:0070969; C:ULK1-ATG13-FIP200 complex; IPI:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0000045; P:autophagic vacuole assembly; IMP:UniProtKB.::GO:0048675; P:axon extension; IMP:MGI.::GO:0021707; P:cerebellar granule cell differentiation; IMP:MGI.::GO:0048671; P:negative regulation of collateral sprouting; IMP:MGI.::GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0008104; P:protein localization; ISS:UniProtKB.::GO:0021933; P:radial glia guided migration of cerebellar granule cell; IMP:MGI.::GO:0007265; P:Ras protein signal transduction; IDA:MGI.::GO:0031623; P:receptor internalization; IMP:MGI.::GO:0051386; P:regulation of nerve growth factor receptor signaling pathway; IMP:MGI. | 645 | Q15418 | 735 | KS6A1_HUMAN Ribosomal protein S6 kinase alpha... | 344 | 2e-25 | 116 | 27 | 46 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045597; P:positive regulation of cell differentiation; TAS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; TAS:UniProtKB.::GO:2000491; P:positive regulation of hepatic stellate cell activation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043620; P:regulation of DNA-dependent transcription in response to stress; TAS:UniProtKB.::GO:0043555; P:regulation of translation in response to stress; TAS:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome. | 646 | Q21734 | 784 | KS6A1_CAEEL Putative ribosomal protein S6 kin... | 284 | 2e-25 | 116 | 29 | 48 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro. | 647 | Q54QI2 | 941 | Y9877_DICDI Serine/threonine-protein kinase D... | 331 | 2e-25 | 117 | 26 | 44 | GO:0016020; C:membrane; IEA:InterPro. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro. | | | | | | | | | | | 648 | Q6PDN3 | 1941 | MYLK_MOUSE Myosin light chain kinase, smooth ... | 223 | 2e-25 | 118 | 30 | 51 | GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC. | | | | | | | | | | GO:0014820; P:tonic smooth muscle contraction; IMP:UniProtKB. | 649 | Q13177 | 524 | PAK2_HUMAN Serine/threonine-protein kinase PA... | 231 | 2e-25 | 115 | 29 | 55 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0019901; F:protein kinase binding; IPI:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:BHF-UCL.::GO:0030296; F:protein tyrosine kinase activator activity; IDA:BHF-UCL. | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0006921; P:cellular component disassembly involved in apoptotic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:2001271; P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis; IDA:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; TAS:ProtInc.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:BHF-UCL.::GO:2001238; P:positive regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.::GO:0050731; P:positive regulation of peptidyl-tyrosine phosphorylation; IDA:BHF-UCL.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0016032; P:viral reproduction; TAS:Reactome. | 650 | Q15746 | 1914 | MYLK_HUMAN Myosin light chain kinase, smooth ... | 223 | 2e-25 | 118 | 30 | 51 | GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0001725; C:stress fiber; IDA:UniProtKB. | | | | | | | | | | GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0060414; P:aorta smooth muscle tissue morphogenesis; IMP:BHF-UCL.::GO:0032060; P:bleb assembly; IMP:UniProtKB.::GO:0071476; P:cellular hypotonic response; IDA:UniProtKB.::GO:0051928; P:positive regulation of calcium ion transport; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IDA:UniProtKB.::GO:0090303; P:positive regulation of wound healing; IDA:UniProtKB.::GO:0014820; P:tonic smooth muscle contraction; ISS:UniProtKB. | 651 | Q810W7 | 1570 | MAST1_RAT Microtubule-associated serine/threo... | 328 | 2e-25 | 118 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB. | 652 | Q10KY3 | 600 | CAMK1_ORYSJ Calcium/calmodulin-dependent seri... | 213 | 2e-25 | 116 | 31 | 52 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | | 653 | Q9R1L5 | 1570 | MAST1_MOUSE Microtubule-associated serine/thr... | 328 | 2e-25 | 118 | 27 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB. | 654 | Q9SZM3 | 484 | CDPKQ_ARATH Calcium-dependent protein kinase ... | 219 | 2e-25 | 114 | 32 | 50 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. | | | | | | | | | | | 655 | Q1HKZ5 | 959 | M3K13_MOUSE Mitogen-activated protein kinase ... | 279 | 2e-25 | 117 | 28 | 48 | GO:0016020; C:membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC. | | | | | | | | | | | 656 | P35465 | 544 | PAK1_RAT Serine/threonine-protein kinase PAK ... | 235 | 2e-25 | 115 | 27 | 54 | GO:0030424; C:axon; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0030425; C:dendrite; IDA:RGD.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0014704; C:intercalated disc; IDA:RGD.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0031965; C:nuclear membrane; IDA:RGD.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0001726; C:ruffle; ISS:UniProtKB.::GO:0030018; C:Z disc; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; ISS:UniProtKB.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0048754; P:branching morphogenesis of a tube; ISS:UniProtKB.::GO:0032869; P:cellular response to insulin stimulus; IDA:RGD.::GO:0033554; P:cellular response to stress; IDA:RGD.::GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; ISS:UniProtKB.::GO:0048812; P:neuron projection morphogenesis; IMP:RGD.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; ISS:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:RGD.::GO:0007264; P:small GTPase mediated signal transduction; TAS:RGD.::GO:0042060; P:wound healing; ISS:UniProtKB. | 657 | Q3SYZ2 | 384 | MAPK3_BOVIN MAP kinase-activated protein kina... | 292 | 2e-25 | 114 | 27 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB. | | | | | | | | | | GO:0044351; P:macropinocytosis; ISS:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0006950; P:response to stress; ISS:UniProtKB.::GO:0002224; P:toll-like receptor signaling pathway; ISS:UniProtKB. | 658 | Q10292 | 445 | MEK1_SCHPO Meiosis-specific serine/threonine-... | 225 | 2e-25 | 114 | 32 | 52 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0030998; C:linear element; IDA:PomBase. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase. | | | | | | | | | | GO:0051598; P:meiotic recombination checkpoint; IMP:PomBase.::GO:0090006; P:regulation of linear element assembly; IGI:PomBase. | 659 | Q9HBH9 | 465 | MKNK2_HUMAN MAP kinase-interacting serine/thr... | 216 | 2e-25 | 114 | 34 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0071243; P:cellular response to arsenic-containing substance; IDA:UniProtKB.::GO:0030097; P:hemopoiesis; IDA:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW. | 660 | Q13153 | 545 | PAK1_HUMAN Serine/threonine-protein kinase PA... | 235 | 2e-25 | 115 | 27 | 54 | GO:0030424; C:axon; ISS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0014704; C:intercalated disc; ISS:UniProtKB.::GO:0031965; C:nuclear membrane; ISS:UniProtKB.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB.::GO:0030018; C:Z disc; ISS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005518; F:collagen binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB. | | | | | | | | | | GO:0031532; P:actin cytoskeleton reorganization; IDA:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0048754; P:branching morphogenesis of a tube; IMP:UniProtKB.::GO:0060244; P:negative regulation of cell proliferation involved in contact inhibition; IMP:UniProtKB.::GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IDA:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; IMP:UniProtKB.::GO:0033138; P:positive regulation of peptidyl-serine phosphorylation; IDA:UniProtKB.::GO:0051496; P:positive regulation of stress fiber assembly; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0042060; P:wound healing; IMP:UniProtKB. | 661 | Q07250 | 415 | KCCS_MALDO Calcium/calmodulin-dependent serin... | 204 | 2e-25 | 114 | 32 | 55 | | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC. | | | | | | | | | | |