UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR097C

Length:

1242

Number of sequences:

5887

Description:

YDR097C MSH6 SGDID:S000002504, Chr IV from 643837-640109, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; potentially phosphorylated by Cdc28p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	Q03834	1242	MSH6_YEAST DNA mismatch repair protein MSH6 O...	1242	0	2586	100	100	GO:0032301; C:MutSalpha complex; IPI:SGD.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
									GO:0005524; F:ATP binding; IDA:SGD.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IDA:SGD.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IMP:SGD.::GO:0045910; P:negative regulation of DNA recombination; IBA:RefGenome.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0009411; P:response to UV; IBA:RefGenome.
2	O74502	1254	MSH6_SCHPO DNA mismatch repair protein msh6 O...	1118	0	828	40	61	GO:0005829; C:cytosol; IDA:PomBase.::GO:0032301; C:MutSalpha complex; ISS:RefGenome.::GO:0000228; C:nuclear chromosome; ISS:RefGenome.
									GO:0005524; F:ATP binding; ISS:PomBase.::GO:0003684; F:damaged DNA binding; ISS:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; ISS:RefGenome.::GO:0000400; F:four-way junction DNA binding; ISS:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; ISS:PomBase.::GO:0032138; F:single base insertion or deletion binding; ISS:RefGenome.
									GO:0043570; P:maintenance of DNA repeat elements; IMP:PomBase.::GO:0000710; P:meiotic mismatch repair; ISS:RefGenome.::GO:0045910; P:negative regulation of DNA recombination; ISS:RefGenome.::GO:0007131; P:reciprocal meiotic recombination; ISS:RefGenome.::GO:0009411; P:response to UV; ISS:RefGenome.
3	Q55GU9	1260	MSH6_DICDI DNA mismatch repair protein Msh6 O...	940	0	625	38	57	GO:0032301; C:MutSalpha complex; ISS:dictyBase.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
									GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IBA:RefGenome.::GO:0032138; F:single base insertion or deletion binding; IBA:RefGenome.
									GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0045910; P:negative regulation of DNA recombination; IBA:RefGenome.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0009411; P:response to UV; IBA:RefGenome.
4	P54276	1358	MSH6_MOUSE DNA mismatch repair protein Msh6 O...	1163	2e-165	535	32	50	GO:0032301; C:MutSalpha complex; IDA:MGI.::GO:0000790; C:nuclear chromatin; IDA:MGI.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IDA:MGI.
									GO:0008340; P:determination of adult lifespan; IMP:MGI.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IMP:MGI.::GO:0045190; P:isotype switching; IMP:MGI.::GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0045910; P:negative regulation of DNA recombination; IMP:MGI.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0009411; P:response to UV; IMP:MGI.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IMP:MGI.
5	P52701	1360	MSH6_HUMAN DNA mismatch repair protein Msh6 O...	1124	8e-163	528	32	50	GO:0032301; C:MutSalpha complex; IDA:HGNC.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0008340; P:determination of adult lifespan; ISS:BHF-UCL.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; ISS:BHF-UCL.::GO:0045190; P:isotype switching; ISS:BHF-UCL.::GO:0000710; P:meiotic mismatch repair; ISS:BHF-UCL.::GO:0045910; P:negative regulation of DNA recombination; IDA:BHF-UCL.::GO:0051096; P:positive regulation of helicase activity; IDA:BHF-UCL.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0009411; P:response to UV; ISS:BHF-UCL.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; ISS:BHF-UCL.
6	O04716	1324	MSH6_ARATH DNA mismatch repair protein Msh6-1...	962	9e-154	503	33	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IDA:TAIR.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; ISS:TAIR.::GO:0006290; P:pyrimidine dimer repair; IMP:TAIR.
7	Q9VUM0	1190	MSH6_DROME Probable DNA mismatch repair prote...	958	4e-122	413	30	48	GO:0032301; C:MutSalpha complex; IBA:RefGenome.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IBA:RefGenome.::GO:0032138; F:single base insertion or deletion binding; IBA:RefGenome.
									GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IBA:RefGenome.::GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IMP:FlyBase.::GO:0045910; P:negative regulation of DNA recombination; IBA:RefGenome.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0009411; P:response to UV; IBA:RefGenome.
8	Q8RA71	869	MUTS_THETN DNA mismatch repair protein MutS O...	892	3e-96	333	29	50
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
9	Q8KCC0	878	MUTS_CHLTE DNA mismatch repair protein MutS O...	866	4e-96	333	29	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
10	A4XL47	863	MUTS_CALS8 DNA mismatch repair protein MutS O...	872	1e-95	332	29	50
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
11	B9MJU0	863	MUTS_ANATD DNA mismatch repair protein MutS O...	877	4e-95	330	29	50
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
12	B3QPY5	876	MUTS_CHLP8 DNA mismatch repair protein MutS O...	864	2e-92	323	29	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
13	Q0AYB5	859	MUTS_SYNWW DNA mismatch repair protein MutS O...	869	3e-91	319	27	51
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
14	B3EEE1	871	MUTS_CHLL2 DNA mismatch repair protein MutS O...	889	4e-91	319	29	48
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
15	P20585	1137	MSH3_HUMAN DNA mismatch repair protein Msh3 O...	913	2e-89	318	27	46	GO:0032302; C:MutSbeta complex; IDA:HGNC.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
									GO:0043570; P:maintenance of DNA repeat elements; IMP:HGNC.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0045910; P:negative regulation of DNA recombination; IDA:BHF-UCL.::GO:0051096; P:positive regulation of helicase activity; IDA:BHF-UCL.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0016447; P:somatic recombination of immunoglobulin gene segments; IBA:RefGenome.
16	Q3ZYA0	858	MUTS_DEHSC DNA mismatch repair protein MutS O...	872	1e-87	308	28	48
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
17	A4J5Q6	868	MUTS_DESRM DNA mismatch repair protein MutS O...	885	2e-87	308	29	48
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
18	B7VK59	853	MUTS_VIBSL DNA mismatch repair protein MutS O...	876	2e-87	308	28	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
19	B8I2Q5	873	MUTS_CLOCE DNA mismatch repair protein MutS O...	877	2e-87	308	28	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
20	B5YJY3	852	MUTS_THEYD DNA mismatch repair protein MutS O...	873	3e-87	307	29	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
21	Q5QUB6	871	MUTS_IDILO DNA mismatch repair protein MutS O...	876	6e-87	306	27	48
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
22	A5ILG0	793	MUTS_THEP1 DNA mismatch repair protein MutS O...	877	6e-86	302	28	48
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
23	A5FQC0	858	MUTS_DEHSB DNA mismatch repair protein MutS O...	872	8e-86	303	28	47
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
24	P0CO92	1191	MSH3_CRYNJ DNA mismatch repair protein MSH3 O...	937	9e-86	308	27	47	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
25	C5BMR5	864	MUTS_TERTT DNA mismatch repair protein MutS O...	878	1e-85	303	27	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
26	A6LG92	870	MUTS_PARD8 DNA mismatch repair protein MutS O...	891	1e-85	303	27	47
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
27	A7MTT8	853	MUTS_VIBHB DNA mismatch repair protein MutS O...	876	1e-85	302	27	48
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
28	P0CO93	1191	MSH3_CRYNB DNA mismatch repair protein MSH3 O...	937	3e-85	306	27	47	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
29	Q31F87	871	MUTS_THICR DNA mismatch repair protein MutS O...	869	7e-85	300	27	48
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
30	Q87LQ9	853	MUTS_VIBPA DNA mismatch repair protein MutS O...	883	9e-85	300	28	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
31	C3LS25	862	MUTS_VIBCM DNA mismatch repair protein MutS O...	876	1e-84	300	27	47
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.

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