UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR097C

Length:

1242

Number of sequences:

5887

Description:

YDR097C MSH6 SGDID:S000002504, Chr IV from 643837-640109, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; potentially phosphorylated by Cdc28p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
631	A4WVX8	876	MUTS_RHOS5 DNA mismatch repair protein MutS O...	879	7e-52	201	24	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
632	P43248	917	MSH2_DROME DNA mismatch repair protein spellc...	561	7e-52	201	27	48	GO:0032301; C:MutSalpha complex; IBA:RefGenome.::GO:0032302; C:MutSbeta complex; IBA:RefGenome.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IBA:RefGenome.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0032138; F:single base insertion or deletion binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
									GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IBA:RefGenome.::GO:0006302; P:double-strand break repair; IBA:RefGenome.::GO:0031573; P:intra-S DNA damage checkpoint; IBA:RefGenome.::GO:0043570; P:maintenance of DNA repeat elements; IMP:FlyBase.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006301; P:postreplication repair; ISS:UniProtKB.::GO:0010224; P:response to UV-B; IBA:RefGenome.::GO:0010165; P:response to X-ray; IBA:RefGenome.
633	Q9XGC9	942	MSH2_MAIZE DNA mismatch repair protein MSH2 O...	786	2e-51	200	26	44	GO:0032301; C:MutSalpha complex; IEA:InterPro.::GO:0032302; C:MutSbeta complex; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
634	Q9HSM2	871	MUTS1_HALSA DNA mismatch repair protein MutS ...	886	5e-51	198	24	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
635	B0R2T0	871	MUTS1_HALS3 DNA mismatch repair protein MutS ...	886	5e-51	198	24	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
636	A1WRJ3	871	MUTS_VEREI DNA mismatch repair protein MutS O...	205	0.000000004	65.1	23	46
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
637	Q9PCR2	868	MUTS_XYLFA DNA mismatch repair protein MutS O...	135	0.000000000001	76.6	33	56
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
638	Q3IYI5	875	MUTS_RHOS4 DNA mismatch repair protein MutS O...	883	9e-51	197	24	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
639	A3PNR5	880	MUTS_RHOS1 DNA mismatch repair protein MutS O...	883	2e-50	197	24	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
640	A1TNU7	890	MUTS_ACIAC DNA mismatch repair protein MutS O...	204	0.0000000000008	77	26	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
641	A7NPT5	1088	MUTS_ROSCS DNA mismatch repair protein MutS O...	478	6e-24	113	21	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
642	A5UZK7	1085	MUTS_ROSS1 DNA mismatch repair protein MutS O...	443	3e-21	104	21	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
643	Q2J2S1	911	MUTS_RHOP2 DNA mismatch repair protein MutS O...	203	0.000000000001	76.3	26	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
644	Q59Y41	1037	MSH3_CANAL DNA mismatch repair protein MSH3 O...	370	7e-41	167	31	53	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
645	A7Z4X5	862	MUTS_BACA2 DNA mismatch repair protein MutS O...	431	9e-27	122	26	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
646	P70755	855	MUTS_AQUPY DNA mismatch repair protein MutS O...	118	0.00000000002	72.4	34	54
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
647	O15457	936	MSH4_HUMAN MutS protein homolog 4 OS=Homo sap...	744	2e-38	159	24	44	GO:0000795; C:synaptonemal complex; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
									GO:0051026; P:chiasma assembly; IBA:RefGenome.::GO:0045143; P:homologous chromosome segregation; IBA:RefGenome.::GO:0006298; P:mismatch repair; IEA:InterPro.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
648	P61673	849	MUTS_WOLPM DNA mismatch repair protein MutS O...	412	4e-24	113	26	48
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
649	C0R5H4	854	MUTS_WOLWR DNA mismatch repair protein MutS O...	211	1e-37	156	39	58
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
650	O13921	941	MSH1_SCHPO MutS protein homolog 1 OS=Schizosa...	370	0.0000000000003	78.6	22	44	GO:0032300; C:mismatch repair complex; ISS:RefGenome.::GO:0005739; C:mitochondrion; IDA:PomBase.::GO:0000228; C:nuclear chromosome; ISS:RefGenome.
									GO:0005524; F:ATP binding; ISS:PomBase.::GO:0003684; F:damaged DNA binding; ISS:RefGenome.::GO:0032139; F:dinucleotide insertion or deletion binding; ISS:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; ISS:PomBase.::GO:0032137; F:guanine/thymine mispair binding; ISS:RefGenome.::GO:0000404; F:loop DNA binding; ISS:RefGenome.
									GO:0043570; P:maintenance of DNA repeat elements; ISS:RefGenome.::GO:0000710; P:meiotic mismatch repair; ISS:RefGenome.::GO:0043504; P:mitochondrial DNA repair; ISS:PomBase.::GO:0007131; P:reciprocal meiotic recombination; ISS:RefGenome.
651	Q99MT2	958	MSH4_MOUSE MutS protein homolog 4 OS=Mus musc...	745	4e-34	145	24	43	GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000795; C:synaptonemal complex; IDA:MGI.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
									GO:0051026; P:chiasma assembly; IBA:RefGenome.::GO:0007292; P:female gamete generation; IMP:MGI.::GO:0045143; P:homologous chromosome segregation; IBA:RefGenome.::GO:0006298; P:mismatch repair; IEA:InterPro.::GO:0001541; P:ovarian follicle development; IMP:MGI.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IMP:MGI.
652	O43196	834	MSH5_HUMAN MutS protein homolog 5 OS=Homo sap...	783	1e-33	144	23	43	GO:0000795; C:synaptonemal complex; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
									GO:0051026; P:chiasma assembly; IBA:RefGenome.::GO:0045143; P:homologous chromosome segregation; IBA:RefGenome.::GO:0007136; P:meiotic prophase II; TAS:ProtInc.::GO:0006298; P:mismatch repair; TAS:ProtInc.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
653	Q23405	842	HIM14_CAEEL MutS protein homolog him-14 OS=Ca...	778	6e-32	138	23	43	GO:0000795; C:synaptonemal complex; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0051026; P:chiasma assembly; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.::GO:0045143; P:homologous chromosome segregation; IMP:WormBase.::GO:0006298; P:mismatch repair; IEA:InterPro.::GO:0000239; P:pachytene; IMP:UniProtKB.::GO:0000712; P:resolution of meiotic recombination intermediates; IMP:UniProtKB.
654	P40965	878	MSH4_YEAST MutS protein homolog 4 OS=Saccharo...	684	7e-32	138	23	44	GO:0000795; C:synaptonemal complex; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0051026; P:chiasma assembly; IBA:RefGenome.::GO:0045143; P:homologous chromosome segregation; IBA:RefGenome.::GO:0006298; P:mismatch repair; IEA:InterPro.::GO:0007131; P:reciprocal meiotic recombination; IMP:SGD.
655	Q9QUM7	833	MSH5_MOUSE MutS protein homolog 5 OS=Mus musc...	634	7e-32	138	24	43	GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000795; C:synaptonemal complex; IDA:MGI.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
									GO:0051026; P:chiasma assembly; IBA:RefGenome.::GO:0007292; P:female gamete generation; IMP:MGI.::GO:0045143; P:homologous chromosome segregation; IBA:RefGenome.::GO:0006298; P:mismatch repair; IEA:InterPro.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
656	Q6MG62	831	MSH5_RAT MutS protein homolog 5 OS=Rattus nor...	631	1e-31	137	24	44	GO:0000795; C:synaptonemal complex; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
									GO:0051026; P:chiasma assembly; IBA:RefGenome.::GO:0045143; P:homologous chromosome segregation; IBA:RefGenome.::GO:0006298; P:mismatch repair; IEA:InterPro.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
657	Q19272	1369	MSH5_CAEEL MutS protein homolog 5 OS=Caenorha...	676	4e-29	130	22	43	GO:0000795; C:synaptonemal complex; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0051026; P:chiasma assembly; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0045143; P:homologous chromosome segregation; IMP:WormBase.::GO:0006298; P:mismatch repair; IEA:InterPro.::GO:0007131; P:reciprocal meiotic recombination; IMP:UniProtKB.
658	P25846	959	MSH1_YEAST DNA mismatch repair protein MSH1, ...	455	0.0000002	59.3	22	40	GO:0032300; C:mismatch repair complex; IBA:RefGenome.::GO:0005739; C:mitochondrion; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0032139; F:dinucleotide insertion or deletion binding; IDA:SGD.::GO:0008094; F:DNA-dependent ATPase activity; IDA:SGD.::GO:0032137; F:guanine/thymine mispair binding; IDA:SGD.
									GO:0006298; P:mismatch repair; IMP:SGD.::GO:0043504; P:mitochondrial DNA repair; IMP:SGD.
659	O94065	803	MSH4_CANAX MutS protein homolog 4 OS=Candida ...	636	1e-26	121	23	46
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:0006298; P:mismatch repair; IEA:InterPro.
660	Q5UQU6	1124	MUTSL_MIMIV Putative DNA mismatch repair prot...	668	6e-25	116	23	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
661	Q12175	901	MSH5_YEAST MutS protein homolog 5 OS=Saccharo...	140	0.00005	51.6	29	49	GO:0000795; C:synaptonemal complex; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0051026; P:chiasma assembly; IBA:RefGenome.::GO:0045143; P:homologous chromosome segregation; IBA:RefGenome.::GO:0006298; P:mismatch repair; IEA:InterPro.::GO:0007131; P:reciprocal meiotic recombination; IMP:SGD.

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