UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR097C

Length:

1242

Number of sequences:

5887

Description:

YDR097C MSH6 SGDID:S000002504, Chr IV from 643837-640109, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; potentially phosphorylated by Cdc28p"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
601	P57504	802	MUTS_BUCAI DNA mismatch repair protein MutS O...	888	5e-61	229	26	48
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
602	Q4FV41	1058	MUTS_PSYA2 DNA mismatch repair protein MutS O...	963	9e-61	231	26	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
603	Q89VX1	912	MUTS_BRAJA DNA mismatch repair protein MutS O...	924	1e-60	229	25	45	GO:0032300; C:mismatch repair complex; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
									GO:0006298; P:mismatch repair; IBA:RefGenome.
604	B8D7V9	802	MUTS_BUCAT DNA mismatch repair protein MutS O...	888	1e-60	228	25	48
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
605	B8D9K7	802	MUTS_BUCA5 DNA mismatch repair protein MutS O...	888	2e-60	227	25	48
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
606	A9NGL6	841	MUTS_ACHLI DNA mismatch repair protein MutS O...	891	3e-60	227	25	46
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
607	A5DYV8	993	MSH3_LODEL DNA mismatch repair protein MSH3 O...	201	0.00000002	62.8	26	45	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
608	A5ETJ3	910	MUTS_BRASB DNA mismatch repair protein MutS O...	908	5e-60	227	25	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
609	Q0AK91	897	MUTS_MARMM DNA mismatch repair protein MutS O...	894	8e-60	226	24	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
610	P43247	935	MSH2_MOUSE DNA mismatch repair protein Msh2 O...	784	7e-59	223	24	45	GO:0032301; C:MutSalpha complex; IDA:MGI.::GO:0032302; C:MutSbeta complex; IBA:RefGenome.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019237; F:centromeric DNA binding; IDA:MGI.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
									GO:0006915; P:apoptotic process; IMP:MGI.::GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0007050; P:cell cycle arrest; IMP:MGI.::GO:0008340; P:determination of adult lifespan; IMP:MGI.::GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IBA:RefGenome.::GO:0006302; P:double-strand break repair; IMP:MGI.::GO:0007281; P:germ cell development; IMP:MGI.::GO:0001701; P:in utero embryonic development; IGI:MGI.::GO:0031573; P:intra-S DNA damage checkpoint; IGI:MGI.::GO:0045190; P:isotype switching; IMP:MGI.::GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0008584; P:male gonad development; IMP:MGI.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006119; P:oxidative phosphorylation; IMP:MGI.::GO:0006301; P:postreplication repair; ISS:UniProtKB.::GO:0010224; P:response to UV-B; IMP:MGI.::GO:0010165; P:response to X-ray; IMP:MGI.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IMP:MGI.
611	O13396	937	MSH2_NEUCR DNA mismatch repair protein msh-2 ...	746	8e-59	223	25	45	GO:0032301; C:MutSalpha complex; IBA:RefGenome.::GO:0032302; C:MutSbeta complex; IBA:RefGenome.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IBA:RefGenome.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0032138; F:single base insertion or deletion binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
									GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006301; P:postreplication repair; IBA:RefGenome.::GO:0000735; P:removal of nonhomologous ends; IBA:RefGenome.
612	Q9AC54	903	MUTS_CAUCR DNA mismatch repair protein MutS O...	901	1e-58	222	26	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
613	Q553L4	937	MSH2_DICDI DNA mismatch repair protein Msh2 O...	559	5e-58	221	28	50	GO:0032301; C:MutSalpha complex; ISS:dictyBase.::GO:0032302; C:MutSbeta complex; ISS:dictyBase.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
									GO:0005524; F:ATP binding; ISS:dictyBase.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IBA:RefGenome.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0042803; F:protein homodimerization activity; ISS:dictyBase.::GO:0032138; F:single base insertion or deletion binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
									GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006301; P:postreplication repair; ISS:dictyBase.
614	Q9SMV7	1109	MSH7_ARATH DNA mismatch repair protein Msh6-2...	294	1e-53	209	40	55
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
615	P25336	1018	MSH3_YEAST DNA mismatch repair protein MSH3 O...	906	2e-57	220	25	45	GO:0005737; C:cytoplasm; IDA:SGD.::GO:0032302; C:MutSbeta complex; IPI:SGD.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0032135; F:DNA insertion or deletion binding; IDA:SGD.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IMP:SGD.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0000735; P:removal of nonhomologous ends; IMP:SGD.
616	A6ZTR3	1018	MSH3_YEAS7 DNA mismatch repair protein MSH3 O...	906	2e-57	220	25	45	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
617	P54275	933	MSH2_RAT DNA mismatch repair protein Msh2 OS=...	784	2e-57	219	25	45	GO:0032301; C:MutSalpha complex; IBA:RefGenome.::GO:0032302; C:MutSbeta complex; IBA:RefGenome.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IBA:RefGenome.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
									GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IBA:RefGenome.::GO:0006302; P:double-strand break repair; IBA:RefGenome.::GO:0031573; P:intra-S DNA damage checkpoint; IBA:RefGenome.::GO:0045190; P:isotype switching; IBA:RefGenome.::GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006301; P:postreplication repair; ISS:UniProtKB.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0010224; P:response to UV-B; IBA:RefGenome.::GO:0010165; P:response to X-ray; IBA:RefGenome.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IBA:RefGenome.::GO:0007283; P:spermatogenesis; IEP:RGD.
618	A5GQ22	885	MUTS_SYNR3 DNA mismatch repair protein MutS O...	261	0.0000000000002	79.3	26	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
619	C5CTL8	885	MUTS_VARPS DNA mismatch repair protein MutS O...	205	0.000000000006	73.9	26	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
620	A9GIM9	918	MUTS_SORC5 DNA mismatch repair protein MutS O...	914	3e-56	215	25	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
621	A6U5G0	915	MUTS_SINMW DNA mismatch repair protein MutS O...	891	4e-56	215	23	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
622	B5EA63	837	MUTS_GEOBB DNA mismatch repair protein MutS O...	894	7e-56	213	23	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
623	Q0A8K3	878	MUTS_ALHEH DNA mismatch repair protein MutS O...	126	0.00000000003	71.6	32	57
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
624	P25847	964	MSH2_YEAST DNA mismatch repair protein MSH2 O...	829	1e-55	214	27	44	GO:0032301; C:MutSalpha complex; IPI:SGD.::GO:0032302; C:MutSbeta complex; IPI:SGD.::GO:0000228; C:nuclear chromosome; IDA:SGD.
									GO:0005524; F:ATP binding; IDA:SGD.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IDA:SGD.::GO:0000400; F:four-way junction DNA binding; IDA:SGD.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0030466; P:chromatin silencing at silent mating-type cassette; IGI:SGD.::GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0006311; P:meiotic gene conversion; IMP:SGD.::GO:0000710; P:meiotic mismatch repair; IMP:SGD.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006301; P:postreplication repair; IBA:RefGenome.::GO:0000735; P:removal of nonhomologous ends; IMP:SGD.
625	Q87CI8	868	MUTS_XYLFT DNA mismatch repair protein MutS O...	202	0.000000000003	74.7	28	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
626	P56883	916	MUTS_RHIME DNA mismatch repair protein MutS O...	907	4e-55	212	24	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
627	Q8K9D2	805	MUTS_BUCAP DNA mismatch repair protein MutS O...	880	5e-54	207	25	47
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
628	A1B095	878	MUTS_PARDP DNA mismatch repair protein MutS O...	881	8e-54	207	23	45
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
629	O66652	859	MUTS_AQUAE DNA mismatch repair protein MutS O...	873	1e-53	206	24	45	GO:0032300; C:mismatch repair complex; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
									GO:0006298; P:mismatch repair; IBA:RefGenome.
630	O24617	937	MSH2_ARATH DNA mismatch repair protein Msh2 O...	740	9e-53	204	25	45	GO:0032301; C:MutSalpha complex; IEA:InterPro.::GO:0032302; C:MutSbeta complex; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:TAIR.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IDA:TAIR.::GO:0030983; F:mismatched DNA binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:TAIR.
									GO:0006298; P:mismatch repair; IMP:TAIR.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IMP:TAIR.::GO:0006290; P:pyrimidine dimer repair; IMP:TAIR.
631	A4WVX8	876	MUTS_RHOS5 DNA mismatch repair protein MutS O...	879	7e-52	201	24	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.

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