Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR096W
Length:
894
Number of sequences:
5887
Description:
YDR096W GIS1 SGDID:S000002503, Chr IV from 637139-639823, Genome Release 64-1-1, Verified ORF, "JmjC domain-containing histone demethylase and transcription factor; involved in expression of genes during nutrient limitation; negatively regulates DPP1 and PHR1; activity is modulated by limited proteasome-mediated proteolysis; has a JmjC and a JmjN domain in the N-terminal region that interact, promoting Gis1p stability and proper transcriptional activity; contains transactivating domains TAD1 and TAD2 downstream of the Jmj domains and a C-terminal DNA binding domain"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
961O00110    214   OVOL3_HUMAN Putative transcription factor ovo...510.005     43.1     37     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
962Q02415    46   KRUP_CUPSA Protein krueppel OS=Cupiennius sal...400.005     40.8     45     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035282; P:segmentation; IEA:UniProtKB-KW.
963Q15935    545   ZNF77_HUMAN Zinc finger protein 77 OS=Homo sa...1001.5     36.2     29     48GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
964Q5R8G9    458   ZN239_PONAB Zinc finger protein 239 OS=Pongo ...550.79     37     35     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
965Q16600    458   ZN239_HUMAN Zinc finger protein 239 OS=Homo s...550.81     37     35     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0003723; F:RNA binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
966Q8IVP9    402   ZN547_HUMAN Zinc finger protein 547 OS=Homo s...1380.38     37.7     25     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
967Q64HY5    480   SP8_CHICK Transcription factor Sp8 OS=Gallus ...540.005     43.9     37     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030326; P:embryonic limb morphogenesis; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
968Q8IXZ3    490   SP8_HUMAN Transcription factor Sp8 OS=Homo sa...540.005     43.9     37     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
969Q9UK11    482   ZN223_HUMAN Zinc finger protein 223 OS=Homo s...602.1     35.8     32     60GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
970Q96MX3    618   ZNF48_HUMAN Zinc finger protein 48 OS=Homo sa...246.6     34.3     50     75GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
971Q5U4E2    545   REPI1_MOUSE Replication initiator 1 OS=Mus mu...491.4     36.2     35     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
972Q2M3X9    581   ZN674_HUMAN Zinc finger protein 674 OS=Homo s...500.29     38.5     40     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
973Q5RAX9    1117   PRD10_PONAB PR domain zinc finger protein 10 ...525.8     34.3     40     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
974Q06730    810   ZN33A_HUMAN Zinc finger protein 33A OS=Homo s...647.3     33.9     31     52GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
975P08042    402   ZFP1_MOUSE Zinc finger protein 1 OS=Mus muscu...481.4     36.2     38     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
976Q0VDQ9    475   FEZF1_MOUSE Fez family zinc finger protein 1 ...960.079     40     29     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:MGI.::GO:0021797; P:forebrain anterior/posterior pattern specification; IGI:MGI.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0021772; P:olfactory bulb development; IMP:MGI.::GO:0045666; P:positive regulation of neuron differentiation; IGI:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
977P18714    675   ZG20_XENLA Gastrula zinc finger protein xFG20...765.6     34.3     32     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
978Q90625    706   ZBT17_CHICK Zinc finger and BTB domain-contai...554.1     34.7     36     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
979Q9GZX5    532   ZN350_HUMAN Zinc finger protein 350 OS=Homo s...502.3     35.4     34     54GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
980Q2VWH6    458   FEZF2_BOVIN Fez family zinc finger protein 2 ...960.41     37.7     28     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
981Q96LW1    612   Z354B_HUMAN Zinc finger protein 354B OS=Homo ...680.91     37     31     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
982Q86XN6    746   ZN761_HUMAN Zinc finger protein 761 OS=Homo s...483.4     35     38     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
983Q9ESP5    455   FEZF2_MOUSE Fez family zinc finger protein 2 ...960.38     38.1     28     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:MGI.::GO:0007413; P:axonal fasciculation; IMP:MGI.::GO:0016358; P:dendrite development; IMP:MGI.::GO:0021542; P:dentate gyrus development; IMP:MGI.::GO:0021797; P:forebrain anterior/posterior pattern specification; IGI:MGI.::GO:0007626; P:locomotory behavior; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
984A6NK53    670   ZN233_HUMAN Zinc finger protein 233 OS=Homo s...520.3     38.5     38     54GO:0005634; C:nucleus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
985Q01872    46   KRUP_LITFO Protein krueppel OS=Lithobius forf...400.006     40.8     43     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035282; P:segmentation; IEA:UniProtKB-KW.
986Q86VK4    478   ZN410_HUMAN Zinc finger protein 410 OS=Homo s...1870.006     43.9     26     40GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
987Q9UIE0    474   ZN230_HUMAN Zinc finger protein 230 OS=Homo s...417.9     33.9     39     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
988P15822    2718   ZEP1_HUMAN Zinc finger protein 40 OS=Homo sap...684.7     34.7     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:ProtInc.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
989Q6ZT77    177   ZN826_HUMAN Putative zinc finger protein 826 ...410.006     42     44     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
990O54963    1069   REST_RAT RE1-silencing transcription factor O...527.2     34.3     27     58GO:0000785; C:chromatin; IDA:RGD.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0005262; F:calcium channel activity; IMP:UniProtKB.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0015271; F:outward rectifier potassium channel activity; ISS:UniProtKB.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060379; P:cardiac muscle cell myoblast differentiation; ISS:UniProtKB.::GO:0035690; P:cellular response to drug; ISS:UniProtKB.::GO:0071257; P:cellular response to electrical stimulus; ISS:UniProtKB.::GO:0071385; P:cellular response to glucocorticoid stimulus; ISS:UniProtKB.::GO:0070933; P:histone H4 deacetylation; ISS:UniProtKB.::GO:0043922; P:negative regulation by host of viral transcription; ISS:UniProtKB.::GO:0032348; P:negative regulation of aldosterone biosynthetic process; IMP:UniProtKB.::GO:2000798; P:negative regulation of amniotic stem cell differentiation; ISS:UniProtKB.::GO:0045955; P:negative regulation of calcium ion-dependent exocytosis; IMP:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:2000065; P:negative regulation of cortisol biosynthetic process; IMP:UniProtKB.::GO:2000706; P:negative regulation of dense core granule biogenesis; IMP:UniProtKB.::GO:0046676; P:negative regulation of insulin secretion; ISS:UniProtKB.::GO:0050768; P:negative regulation of neurogenesis; ISS:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; IMP:RGD.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.::GO:0043280; P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; ISS:UniProtKB.
991P18752    391   ZO72_XENLA Oocyte zinc finger protein XlCOF7....410.035     41.2     46     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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