Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR096W
Length:
894
Number of sequences:
5887
Description:
YDR096W GIS1 SGDID:S000002503, Chr IV from 637139-639823, Genome Release 64-1-1, Verified ORF, "JmjC domain-containing histone demethylase and transcription factor; involved in expression of genes during nutrient limitation; negatively regulates DPP1 and PHR1; activity is modulated by limited proteasome-mediated proteolysis; has a JmjC and a JmjN domain in the N-terminal region that interact, promoting Gis1p stability and proper transcriptional activity; contains transactivating domains TAD1 and TAD2 downstream of the Jmj domains and a C-terminal DNA binding domain"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91P51505    293   ZNF80_MACMU Zinc finger protein 80 OS=Macaca ...510.076     39.7     35     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
92P51503    273   ZNF80_GORGO Zinc finger protein 80 OS=Gorilla...510.069     40     35     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
93Q8TD17    642   ZN398_HUMAN Zinc finger protein 398 OS=Homo s...462.4     35.4     37     50GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
94O75467    553   Z324A_HUMAN Zinc finger protein 324A OS=Homo ...860.026     42     34     48GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
95Q3Y4E1    794   ZN148_BOVIN Zinc finger protein 148 OS=Bos ta...500.00007     50.4     40     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
96P23803    392   ODD_DROME Protein odd-skipped OS=Drosophila m...521.7     35.8     35     50GO:0005634; C:nucleus; IC:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016348; P:imaginal disc-derived leg joint morphogenesis; IMP:FlyBase.::GO:0007443; P:Malpighian tubule morphogenesis; IMP:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007366; P:periodic partitioning by pair rule gene; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
97Q9UQR1    794   ZN148_HUMAN Zinc finger protein 148 OS=Homo s...500.00007     50.4     40     64GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006366; P:transcription from RNA polymerase II promoter; TAS:ProtInc.
98Q8N9K5    499   ZN565_HUMAN Zinc finger protein 565 OS=Homo s...521.4     36.2     37     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
99P18713    197   ZG17_XENLA Gastrula zinc finger protein XlCGF...460.037     40     41     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
100Q5R782    794   ZN148_PONAB Zinc finger protein 148 OS=Pongo ...500.00007     50.4     40     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
101Q61624    794   ZN148_MOUSE Zinc finger protein 148 OS=Mus mu...500.00007     50.4     40     64GO:0005634; C:nucleus; IDA:MGI.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007276; P:gamete generation; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
102Q62806    794   ZN148_RAT Zinc finger protein 148 OS=Rattus n...500.00007     50.4     40     64GO:0005634; C:nucleus; IDA:RGD.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:RGD.::GO:0006461; P:protein complex assembly; IMP:RGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
103O75373    536   ZN737_HUMAN Zinc finger protein 737 OS=Homo s...420.73     37     45     55GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
104O95201    554   ZN205_HUMAN Zinc finger protein 205 OS=Homo s...500.54     37.7     40     62GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
105P18718    196   ZG3_XENLA Gastrula zinc finger protein xLCGF3...640.055     39.7     38     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
106P36197    1114   ZEB1_CHICK Zinc finger E-box-binding homeobox...990.00009     50.1     28     46GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
107A4II20    498   EGR1_XENTR Early growth response protein 1 OS...560.000008     53.1     39     57GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
108Q9P7D9    428   RSV1_SCHPO Zinc finger protein rsv1 OS=Schizo...570.000001     55.5     44     56GO:0005634; C:nucleus; IDA:PomBase.::GO:0005819; C:spindle; IDA:PomBase.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; NAS:PomBase.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IMP:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042149; P:cellular response to glucose starvation; IMP:PomBase.::GO:0010678; P:negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-dependent; IMP:PomBase.::GO:0010674; P:negative regulation of transcription from RNA polymerase II promoter during meiosis; IMP:PomBase.
109P18744    247   ZO20_XENLA Oocyte zinc finger protein XlCOF20...770.72     36.6     26     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
110P18741    140   ZO15_XENLA Oocyte zinc finger protein XlCOF15...490.003     42.4     37     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
111Q14592    562   ZN460_HUMAN Zinc finger protein 460 OS=Homo s...511.3     36.2     35     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
112A0MS83    808   ZN148_DANRE Zinc finger protein 148 OS=Danio ...530.0006     47.4     42     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030097; P:hemopoiesis; IMP:ZFIN.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
113P52288    543   MIG1_KLUMA Regulatory protein MIG1 OS=Kluyver...550.000001     55.8     44     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
114O70494    783   SP3_MOUSE Transcription factor Sp3 OS=Mus mus...590.000001     55.8     41     61GO:0016605; C:PML body; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB.
GO:0003682; F:chromatin binding; IDA:MGI.::GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:MGI.::GO:0003690; F:double-stranded DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0001078; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; IDA:UniProtKB.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0060216; P:definitive hemopoiesis; IGI:MGI.::GO:0048596; P:embryonic camera-type eye morphogenesis; IGI:MGI.::GO:0001892; P:embryonic placenta development; IGI:MGI.::GO:0060136; P:embryonic process involved in female pregnancy; IGI:MGI.::GO:0048706; P:embryonic skeletal system development; IGI:MGI.::GO:0043353; P:enucleate erythrocyte differentiation; IGI:MGI.::GO:0030851; P:granulocyte differentiation; IMP:MGI.::GO:0001889; P:liver development; IGI:MGI.::GO:0030324; P:lung development; IGI:MGI.::GO:0030219; P:megakaryocyte differentiation; IGI:MGI.::GO:0030224; P:monocyte differentiation; IMP:MGI.::GO:0001779; P:natural killer cell differentiation; IMP:MGI.::GO:0001503; P:ossification; IGI:MGI.::GO:0030217; P:T cell differentiation; IMP:MGI.::GO:0001829; P:trophectodermal cell differentiation; IGI:MGI.
115Q8TAF7    563   ZN461_HUMAN Zinc finger protein 461 OS=Homo s...370.76     37     43     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
116Q494X3    552   ZN404_HUMAN Zinc finger protein 404 OS=Homo s...840.13     39.7     27     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
117Q9Y7G2    574   MIG1_CANAX Regulatory protein MIG1 OS=Candida...530.000001     55.5     45     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
118P37275    1124   ZEB1_HUMAN Zinc finger E-box-binding homeobox...990.00006     50.8     28     46GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0070888; F:E-box binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0006955; P:immune response; TAS:ProtInc.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0045666; P:positive regulation of neuron differentiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
119P08046    533   EGR1_MOUSE Early growth response protein 1 OS...560.00001     52.4     39     57GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IDA:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030509; P:BMP signaling pathway; IDA:MGI.::GO:0071480; P:cellular response to gamma radiation; IMP:BHF-UCL.::GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071506; P:cellular response to mycophenolic acid; ISS:UniProtKB.::GO:0072110; P:glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0072303; P:positive regulation of glomerular metanephric mesangial cell proliferation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0009749; P:response to glucose stimulus; IDA:UniProtKB.::GO:0032868; P:response to insulin stimulus; IDA:UniProtKB.::GO:0030217; P:T cell differentiation; IMP:MGI.
120P18146    543   EGR1_HUMAN Early growth response protein 1 OS...560.00001     52.8     39     57GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0035035; F:histone acetyltransferase binding; IPI:BHF-UCL.::GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071504; P:cellular response to heparin; ISS:UniProtKB.::GO:0071506; P:cellular response to mycophenolic acid; ISS:UniProtKB.::GO:0072110; P:glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:BHF-UCL.::GO:0072303; P:positive regulation of glomerular metanephric mesangial cell proliferation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0033233; P:regulation of protein sumoylation; IDA:BHF-UCL.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.
121Q8N782    197   ZN525_HUMAN Zinc finger protein 525 OS=Homo s...410.04     40     46     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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