Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR096W
Length:
894
Number of sequences:
5887
Description:
YDR096W GIS1 SGDID:S000002503, Chr IV from 637139-639823, Genome Release 64-1-1, Verified ORF, "JmjC domain-containing histone demethylase and transcription factor; involved in expression of genes during nutrient limitation; negatively regulates DPP1 and PHR1; activity is modulated by limited proteasome-mediated proteolysis; has a JmjC and a JmjN domain in the N-terminal region that interact, promoting Gis1p stability and proper transcriptional activity; contains transactivating domains TAD1 and TAD2 downstream of the Jmj domains and a C-terminal DNA binding domain"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
901O88282    474   BCL6B_MOUSE B-cell CLL/lymphoma 6 member B pr...460.088     40     43     57GO:0005634; C:nucleus; IDA:MGI.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.
902Q9BWE0    567   REPI1_HUMAN Replication initiator 1 OS=Homo s...549.4     33.5     30     52GO:0005664; C:nuclear origin of replication recognition complex; TAS:ProtInc.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006260; P:DNA replication; TAS:ProtInc.
903Q08AG5    666   ZN844_HUMAN Zinc finger protein 844 OS=Homo s...630.6     37.4     33     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
904Q9BR84    538   ZN559_HUMAN Zinc finger protein 559 OS=Homo s...520.89     37     37     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
905P16372    489   ZFP58_MOUSE Zinc finger protein 58 OS=Mus mus...414.2     34.7     46     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
906O43829    449   ZF161_HUMAN Zinc finger protein 161 homolog O...500.56     37.4     34     50GO:0005634; C:nucleus; TAS:ProtInc.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
907A8MUV8    499   ZN727_HUMAN Putative zinc finger protein 727 ...412.5     35.4     44     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
908Q5EAC5    467   ZN410_BOVIN Zinc finger protein 410 OS=Bos ta...1870.003     44.7     26     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
909B2RUI1    696   ZN551_MOUSE Zinc finger protein 551 OS=Mus mu...500.39     38.1     36     66GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
910Q8TF50    670   ZN526_HUMAN Zinc finger protein 526 OS=Homo s...480.26     38.5     38     65GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
911Q8N8J6    731   ZN615_HUMAN Zinc finger protein 615 OS=Homo s...506.4     34.3     34     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
912Q8N143    479   BCL6B_HUMAN B-cell CLL/lymphoma 6 member B pr...1050.031     41.6     29     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
913B4F6U4    1173   PRD10_XENTR PR domain zinc finger protein 10 ...700.16     39.7     31     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
914Q5R4K8    730   ZN615_PONAB Zinc finger protein 615 OS=Pongo ...506.8     34.3     34     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
915Q9Y6Q3    630   ZFP37_HUMAN Zinc finger protein 37 homolog OS...411.1     36.6     44     61GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
916P10074    688   ZBT48_HUMAN Zinc finger and BTB domain-contai...603.2     35     28     50GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
917Q12041    191   MET32_YEAST Transcriptional regulator MET32 O...500.003     43.1     40     62GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001102; F:RNA polymerase II activating transcription factor binding; IDA:SGD.::GO:0001133; F:sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007346; P:regulation of mitotic cell cycle; IMP:SGD.::GO:0031335; P:regulation of sulfur amino acid metabolic process; IMP:SGD.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
918Q6GL52    857   ZN574_XENTR Zinc finger protein 574 OS=Xenopu...640.46     38.1     31     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
919P19544    449   WT1_HUMAN Wilms tumor protein OS=Homo sapiens...484.8     34.3     35     56GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016607; C:nuclear speck; IDA:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0070742; F:C2H2 zinc finger domain binding; IPI:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035802; P:adrenal cortex formation; ISS:UniProtKB.::GO:0001658; P:branching involved in ureteric bud morphogenesis; IGI:UniProtKB.::GO:0043010; P:camera-type eye development; ISS:UniProtKB.::GO:0060923; P:cardiac muscle cell fate commitment; ISS:BHF-UCL.::GO:0071320; P:cellular response to cAMP; IEP:UniProtKB.::GO:0071371; P:cellular response to gonadotropin stimulus; IDA:UniProtKB.::GO:0060539; P:diaphragm development; ISS:UniProtKB.::GO:0007281; P:germ cell development; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; IMP:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; IDA:UniProtKB.::GO:0030539; P:male genitalia development; ISS:UniProtKB.::GO:0008584; P:male gonad development; IEP:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0072207; P:metanephric epithelium development; IEP:UniProtKB.::GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.::GO:0072284; P:metanephric S-shaped body morphogenesis; IGI:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IGI:UniProtKB.::GO:0030308; P:negative regulation of cell growth; IDA:UniProtKB.::GO:2000195; P:negative regulation of female gonad development; ISS:UniProtKB.::GO:0072302; P:negative regulation of metanephric glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0017148; P:negative regulation of translation; IDA:UniProtKB.::GO:0060421; P:positive regulation of heart growth; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:2001076; P:positive regulation of metanephric ureteric bud development; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0072166; P:posterior mesonephric tubule development; ISS:UniProtKB.::GO:0003156; P:regulation of organ formation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0007530; P:sex determination; IDA:UniProtKB.::GO:0007356; P:thorax and anterior abdomen determination; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.::GO:0061032; P:visceral serous pericardium development; IGI:UniProtKB.
920Q96IR2    970   ZN845_HUMAN Zinc finger protein 845 OS=Homo s...439     33.9     44     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
921Q5R633    688   ZBT48_PONAB Zinc finger and BTB domain-contai...603.3     35     28     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
922Q86T29    641   ZN605_HUMAN Zinc finger protein 605 OS=Homo s...501.2     36.6     36     56GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
923O62651    449   WT1_PIG Wilms tumor protein homolog OS=Sus sc...484.8     34.3     35     56GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0070742; F:C2H2 zinc finger domain binding; ISS:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; ISS:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0035802; P:adrenal cortex formation; ISS:UniProtKB.::GO:0001658; P:branching involved in ureteric bud morphogenesis; ISS:UniProtKB.::GO:0043010; P:camera-type eye development; ISS:UniProtKB.::GO:0071371; P:cellular response to gonadotropin stimulus; ISS:UniProtKB.::GO:0060539; P:diaphragm development; ISS:UniProtKB.::GO:0007281; P:germ cell development; ISS:UniProtKB.::GO:0032836; P:glomerular basement membrane development; ISS:UniProtKB.::GO:0072112; P:glomerular visceral epithelial cell differentiation; ISS:UniProtKB.::GO:0006917; P:induction of apoptosis; ISS:UniProtKB.::GO:0030539; P:male genitalia development; ISS:UniProtKB.::GO:0008584; P:male gonad development; ISS:UniProtKB.::GO:0060231; P:mesenchymal to epithelial transition; ISS:UniProtKB.::GO:0072075; P:metanephric mesenchyme development; ISS:UniProtKB.::GO:0072284; P:metanephric S-shaped body morphogenesis; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0030308; P:negative regulation of cell growth; ISS:UniProtKB.::GO:2000195; P:negative regulation of female gonad development; ISS:UniProtKB.::GO:0072302; P:negative regulation of metanephric glomerular mesangial cell proliferation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0017148; P:negative regulation of translation; ISS:UniProtKB.::GO:0060421; P:positive regulation of heart growth; ISS:UniProtKB.::GO:2000020; P:positive regulation of male gonad development; ISS:UniProtKB.::GO:2001076; P:positive regulation of metanephric ureteric bud development; ISS:UniProtKB.::GO:0072166; P:posterior mesonephric tubule development; ISS:UniProtKB.::GO:0003156; P:regulation of organ formation; ISS:UniProtKB.::GO:0008380; P:RNA splicing; ISS:UniProtKB.::GO:0007530; P:sex determination; ISS:UniProtKB.::GO:0007356; P:thorax and anterior abdomen determination; ISS:UniProtKB.::GO:0001570; P:vasculogenesis; ISS:UniProtKB.::GO:0061032; P:visceral serous pericardium development; ISS:UniProtKB.
924P18736    140   ZG71_XENLA Gastrula zinc finger protein XlCGF...244.5     33.1     54     67GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
925Q9Y330    459   ZBT12_HUMAN Zinc finger and BTB domain-contai...528.9     33.5     35     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
926Q4V348    819   Z658B_HUMAN Zinc finger protein 658B OS=Homo ...411.1     36.6     44     66GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
927Q6ZN11    374   ZN793_HUMAN Zinc finger protein 793 OS=Homo s...482.6     35     33     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
928Q08376    449   ZF161_MOUSE Zinc finger protein 161 OS=Mus mu...500.68     37     34     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
929B7ZRM8    1050   EVI1B_XENLA MDS1 and EVI1 complex locus prote...702.3     35.8     27     49GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0039013; P:pronephric distal tubule morphogenesis; ISS:UniProtKB.::GO:0039022; P:pronephric duct development; ISS:UniProtKB.::GO:0072196; P:proximal/distal pattern formation involved in pronephric nephron development; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
930Q99LH4    468   ZN672_MOUSE Zinc finger protein 672 OS=Mus mu...413.1     35     44     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
931Q8SUR9    449   Z856_ENCCU Zinc finger C2H2 protein ECU08_056...520.003     44.7     42     58GO:0005622; C:intracellular; IEA:InterPro.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
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