Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR096W
Length:
894
Number of sequences:
5887
Description:
YDR096W GIS1 SGDID:S000002503, Chr IV from 637139-639823, Genome Release 64-1-1, Verified ORF, "JmjC domain-containing histone demethylase and transcription factor; involved in expression of genes during nutrient limitation; negatively regulates DPP1 and PHR1; activity is modulated by limited proteasome-mediated proteolysis; has a JmjC and a JmjN domain in the N-terminal region that interact, promoting Gis1p stability and proper transcriptional activity; contains transactivating domains TAD1 and TAD2 downstream of the Jmj domains and a C-terminal DNA binding domain"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
481Q8BQC8    711   RBAK_MOUSE RB-associated KRAB zinc finger pro...582.3     35.8     33     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
482Q96H40    463   ZN486_HUMAN Zinc finger protein 486 OS=Homo s...328.3     33.5     50     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
483Q9UDV7    671   ZN282_HUMAN Zinc finger protein 282 OS=Homo s...552.7     35.4     35     49GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0045892; P:negative regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
484Q08DS3    267   OSR1_BOVIN Protein odd-skipped-related 1 OS=B...390.19     38.5     44     54GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0072111; P:cell proliferation involved in kidney development; ISS:UniProtKB.::GO:0007507; P:heart development; ISS:UniProtKB.::GO:0072143; P:mesangial cell development; ISS:UniProtKB.::GO:0072239; P:metanephric glomerulus vasculature development; ISS:UniProtKB.::GO:0072259; P:metanephric interstitial cell development; ISS:UniProtKB.::GO:0072162; P:metanephric mesenchymal cell differentiation; ISS:UniProtKB.::GO:0072234; P:metanephric nephron tubule development; ISS:UniProtKB.::GO:0072208; P:metanephric smooth muscle tissue development; ISS:UniProtKB.::GO:0072183; P:negative regulation of nephron tubule epithelial cell differentiation; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.::GO:2000543; P:positive regulation of gastrulation; ISS:UniProtKB.::GO:0048793; P:pronephros development; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0072184; P:renal vesicle progenitor cell differentiation; ISS:UniProtKB.::GO:0072168; P:specification of anterior mesonephric tubule identity; ISS:UniProtKB.::GO:0072169; P:specification of posterior mesonephric tubule identity; ISS:UniProtKB.::GO:0048863; P:stem cell differentiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0072190; P:ureter urothelium development; ISS:UniProtKB.
485Q07231    555   ZSC21_MOUSE Zinc finger and SCAN domain-conta...502.4     35.4     36     62GO:0005634; C:nucleus; IDA:MGI.
GO:0003677; F:DNA binding; IDA:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0048477; P:oogenesis; IEA:UniProtKB-KW.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
486Q13886    244   KLF9_HUMAN Krueppel-like factor 9 OS=Homo sap...450.39     37.4     38     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0097067; P:cellular response to thyroid hormone stimulus; IDA:UniProtKB.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
487P54785    490   MOT3_YEAST Transcriptional activator/represso...580.00009     49.7     41     57GO:0005634; C:nucleus; IDA:SGD.
GO:0001102; F:RNA polymerase II activating transcription factor binding; IPI:SGD.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071474; P:cellular hyperosmotic response; IMP:SGD.::GO:0010895; P:negative regulation of ergosterol biosynthetic process; IMP:SGD.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
488O94131    420   CREA_GIBFU DNA-binding protein creA OS=monili...520.00009     49.7     42     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
489Q03923    595   ZNF85_HUMAN Zinc finger protein 85 OS=Homo sa...970.16     39.3     32     45GO:0005634; C:nucleus; TAS:ProtInc.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
490P17023    458   ZNF19_HUMAN Zinc finger protein 19 OS=Homo sa...1385.1     34.3     25     43GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
491Q5R7I8    446   ZNF19_PONAB Zinc finger protein 19 OS=Pongo a...308     33.9     43     77GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
492O43296    627   ZN264_HUMAN Zinc finger protein 264 OS=Homo s...1462.9     35.4     23     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
493P14404    1042   EVI1_MOUSE MDS1 and EVI1 complex locus protei...704.7     34.7     27     49GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0035115; P:embryonic forelimb morphogenesis; IMP:MGI.::GO:0035116; P:embryonic hindlimb morphogenesis; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0071425; P:hemopoietic stem cell proliferation; IMP:UniProtKB.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0006954; P:inflammatory response; IMP:MGI.::GO:0046329; P:negative regulation of JNK cascade; ISS:UniProtKB.::GO:0043069; P:negative regulation of programmed cell death; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0001780; P:neutrophil homeostasis; IMP:MGI.::GO:0060039; P:pericardium development; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0009791; P:post-embryonic development; IMP:MGI.::GO:0051726; P:regulation of cell cycle; ISS:UniProtKB.::GO:0042127; P:regulation of cell proliferation; IMP:MGI.::GO:0009617; P:response to bacterium; IMP:MGI.::GO:0009605; P:response to external stimulus; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
494Q969J2    545   ZKSC4_HUMAN Zinc finger protein with KRAB and...910.018     42.4     30     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
495Q9Y2H8    683   ZN510_HUMAN Zinc finger protein 510 OS=Homo s...506.4     34.3     36     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
496Q03924    483   ZN117_HUMAN Zinc finger protein 117 OS=Homo s...480.11     39.7     42     56GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
497Q32M78    642   ZN699_HUMAN Zinc finger protein 699 OS=Homo s...414.9     34.7     41     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
498A7MBI1    524   ZN642_BOVIN Zinc finger protein 642 OS=Bos ta...413.5     35     37     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
499A2T759    682   ZNF16_PANTR Zinc finger protein 16 OS=Pan tro...500.42     38.1     38     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
500Q9HCL3    533   ZFP14_HUMAN Zinc finger protein 14 homolog OS...411.1     36.6     41     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
501Q03081    177   MET31_YEAST Transcriptional regulator MET31 O...530.0001     47.4     43     58GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0001133; F:sequence-specific transcription regulatory region DNA binding RNA polymerase II transcription factor recruiting transcription factor activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031335; P:regulation of sulfur amino acid metabolic process; IMP:SGD.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
502Q6ZTB9    187   ZN833_HUMAN Putative zinc finger protein 833 ...341.8     35     41     59GO:0005622; C:intracellular; IEA:InterPro.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
503P08045    1350   XFIN_XENLA Zinc finger protein Xfin OS=Xenopu...483.4     35     35     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
504P18729    336   ZG57_XENLA Gastrula zinc finger protein XlCGF...502.8     35     40     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
505P51522    516   ZNF83_HUMAN Zinc finger protein 83 OS=Homo sa...415.3     34.3     44     59GO:0005634; C:nucleus; NAS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
506Q01713    244   KLF9_RAT Krueppel-like factor 9 OS=Rattus nor...450.44     37.4     38     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
507P79288    244   KLF9_PIG Krueppel-like factor 9 OS=Sus scrofa...450.44     37.4     38     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
508A6QNZ0    479   ZN187_BOVIN Zinc finger protein 187 OS=Bos ta...375.2     34.3     43     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
509O59958    430   CRE1_NEUCR DNA-binding protein cre-1 OS=1257 ...520.0001     49.3     42     62GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
510O94130    435   CREA_BOTFU DNA-binding protein creA OS=Botryo...520.0001     49.3     44     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
511Q5T5D7    378   ZN684_HUMAN Zinc finger protein 684 OS=Homo s...500.15     39.3     36     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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