Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR096W
Length:
894
Number of sequences:
5887
Description:
YDR096W GIS1 SGDID:S000002503, Chr IV from 637139-639823, Genome Release 64-1-1, Verified ORF, "JmjC domain-containing histone demethylase and transcription factor; involved in expression of genes during nutrient limitation; negatively regulates DPP1 and PHR1; activity is modulated by limited proteasome-mediated proteolysis; has a JmjC and a JmjN domain in the N-terminal region that interact, promoting Gis1p stability and proper transcriptional activity; contains transactivating domains TAD1 and TAD2 downstream of the Jmj domains and a C-terminal DNA binding domain"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361Q3TDE8    283   ZN691_MOUSE Zinc finger protein 691 OS=Mus mu...961.1     36.2     25     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
362Q96JC4    524   ZN479_HUMAN Zinc finger protein 479 OS=Homo s...410.047     40.8     46     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
363A6NKZ1    522   ZN733_HUMAN Zinc finger protein 733 OS=Homo s...681.3     36.2     32     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
364Q8TD23    568   ZN675_HUMAN Zinc finger protein 675 OS=Homo s...410.044     41.2     49     66GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0045453; P:bone resorption; TAS:UniProtKB.::GO:0019221; P:cytokine-mediated signaling pathway; IDA:UniProtKB.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:2000660; P:negative regulation of interleukin-1-mediated signaling pathway; IDA:BHF-UCL.::GO:0046329; P:negative regulation of JNK cascade; IDA:UniProtKB.::GO:0043508; P:negative regulation of JUN kinase activity; IDA:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IDA:BHF-UCL.::GO:0045671; P:negative regulation of osteoclast differentiation; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0010804; P:negative regulation of tumor necrosis factor-mediated signaling pathway; IDA:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
365P18748    537   ZO29_XENLA Oocyte zinc finger protein XlCOF29...500.009     43.1     40     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
366Q8IYN0    542   ZN100_HUMAN Zinc finger protein 100 OS=Homo s...419.6     33.5     44     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
367Q8K1S5    502   KLF11_MOUSE Krueppel-like factor 11 OS=Mus mu...710.00003     51.2     38     58GO:0005634; C:nucleus; IC:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
368P18739    214   ZO10_XENLA Oocyte zinc finger protein XlCOF10...480.13     38.5     35     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
369P17035    718   ZNF28_HUMAN Zinc finger protein 28 OS=Homo sa...506     34.3     38     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
370Q1LZ87    534   ZN397_BOVIN Zinc finger protein 397 OS=Bos ta...480.059     40.8     38     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
371Q10096    585   YAOH_SCHPO Zinc finger protein C11D3.17 OS=Sc...790.00003     51.2     30     56GO:0005634; C:nucleus; IDA:PomBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033554; P:cellular response to stress; IEP:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:InterPro.
372O14709    1029   ZN197_HUMAN Zinc finger protein 197 OS=Homo s...685     34.7     34     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
373O14978    683   ZN263_HUMAN Zinc finger protein 263 OS=Homo s...720.046     41.2     33     53GO:0005737; C:cytoplasm; IDA:HPA.::GO:0015630; C:microtubule cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
374Q2M3W8    571   ZN181_HUMAN Zinc finger protein 181 OS=Homo s...334.7     34.7     55     73GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
375Q5RJ54    466   ZN187_MOUSE Zinc finger protein 187 OS=Mus mu...887.1     33.9     26     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
376A1YF12    682   ZNF16_GORGO Zinc finger protein 16 OS=Gorilla...500.47     37.7     38     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
377Q5REF1    615   ZN181_PONAB Zinc finger protein 181 OS=Pongo ...334.1     34.7     55     73GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
378Q14586    743   ZN267_HUMAN Zinc finger protein 267 OS=Homo s...501.6     36.2     36     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
379P10078    825   ZFP28_MOUSE Zinc finger protein 28 OS=Mus mus...427.4     33.9     38     64GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
380P18743    157   ZO2_XENLA Oocyte zinc finger protein XlCOF2 O...661.9     34.7     30     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
381Q7TNU6    535   ZN250_MOUSE Zinc finger protein 250 OS=Mus mu...500.012     42.7     44     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
382P56671    477   MAZ_MOUSE Myc-associated zinc finger protein ...610.003     44.7     38     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
383Q5CZA5    627   ZN805_HUMAN Zinc finger protein 805 OS=Homo s...480.26     38.5     38     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
384P07247    502   KRUP_DROME Protein krueppel OS=Drosophila mel...580.025     42     38     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003705; F:RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; IDA:FlyBase.::GO:0043565; F:sequence-specific DNA binding; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0006342; P:chromatin silencing; IMP:FlyBase.::GO:0048749; P:compound eye development; IMP:FlyBase.::GO:0007402; P:ganglion mother cell fate determination; TAS:FlyBase.::GO:0061332; P:Malpighian tubule bud morphogenesis; IGI:FlyBase.::GO:0007517; P:muscle organ development; TAS:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0007400; P:neuroblast fate determination; IEP:FlyBase.::GO:0040034; P:regulation of development, heterochronic; NAS:FlyBase.::GO:0035290; P:trunk segmentation; TAS:FlyBase.::GO:0007419; P:ventral cord development; NAS:FlyBase.::GO:0035220; P:wing disc development; IGI:FlyBase.::GO:0007354; P:zygotic determination of anterior/posterior axis, embryo; NAS:FlyBase.
385P56270    477   MAZ_HUMAN Myc-associated zinc finger protein ...610.003     44.7     38     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006369; P:termination of RNA polymerase II transcription; IDA:UniProtKB.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; IDA:UniProtKB.
386O15209    634   ZBT22_HUMAN Zinc finger and BTB domain-contai...550.14     39.7     35     55GO:0005634; C:nucleus; TAS:ProtInc.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
387Q6AY34    276   OSR2_RAT Protein odd-skipped-related 2 OS=Rat...390.14     38.9     44     54GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060349; P:bone morphogenesis; ISS:UniProtKB.::GO:0061029; P:eyelid development in camera-type eye; ISS:UniProtKB.::GO:0001823; P:mesonephros development; ISS:UniProtKB.::GO:0001656; P:metanephros development; ISS:UniProtKB.::GO:0042474; P:middle ear morphogenesis; ISS:UniProtKB.::GO:0042476; P:odontogenesis; ISS:UniProtKB.::GO:0033687; P:osteoblast proliferation; ISS:UniProtKB.::GO:0060021; P:palate development; ISS:UniProtKB.::GO:0050679; P:positive regulation of epithelial cell proliferation; ISS:UniProtKB.
388Q9WUK6    522   ZN238_MOUSE Zinc finger protein 238 OS=Mus mu...380.002     45.1     47     71GO:0005634; C:nucleus; IDA:MGI.
GO:0043565; F:sequence-specific DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007519; P:skeletal muscle tissue development; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
389Q9EPW2    415   KLF15_MOUSE Krueppel-like factor 15 OS=Mus mu...1060.00004     50.8     30     45
GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010001; P:glial cell differentiation; IDA:MGI.::GO:0015758; P:glucose transport; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
390P52743    207   ZN137_HUMAN Putative zinc finger protein 137 ...480.15     38.5     29     63GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
391Q8WV37    535   ZN480_HUMAN Zinc finger protein 480 OS=Homo s...611.8     35.8     31     54GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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