Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR096W
Length:
894
Number of sequences:
5887
Description:
YDR096W GIS1 SGDID:S000002503, Chr IV from 637139-639823, Genome Release 64-1-1, Verified ORF, "JmjC domain-containing histone demethylase and transcription factor; involved in expression of genes during nutrient limitation; negatively regulates DPP1 and PHR1; activity is modulated by limited proteasome-mediated proteolysis; has a JmjC and a JmjN domain in the N-terminal region that interact, promoting Gis1p stability and proper transcriptional activity; contains transactivating domains TAD1 and TAD2 downstream of the Jmj domains and a C-terminal DNA binding domain"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31Q62240    1548   KDM5D_MOUSE Lysine-specific demethylase 5D OS...392.1     35.8     38     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
32Q6IQX0    1503   KD5BB_DANRE Lysine-specific demethylase 5B-B ...810.14     39.7     31     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); ISS:UniProtKB.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); ISS:UniProtKB.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
33O94691    752   JMJ3_SCHPO Lid2 complex component jmj3 OS=Sch...3120.000000000000007     82.8     24     41GO:0005829; C:cytosol; IDA:PomBase.::GO:0048189; C:Lid2 complex; IDA:PomBase.::GO:0000790; C:nuclear chromatin; IC:PomBase.
GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:PomBase.
GO:0006338; P:chromatin remodeling; IC:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IC:PomBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
34P47156    728   JHD2_YEAST Histone demethylase JHD2 OS=Saccha...1120.0000000000001     78.6     38     54GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0032453; F:histone demethylase activity (H3-K4 specific); IMP:SGD.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
35Q6BDA0    1340   ELF6_ARATH Probable lysine-specific demethyla...1820.0000000000004     77.4     28     46GO:0005634; C:nucleus; IDA:TAIR.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033169; P:histone H3-K9 demethylation; IMP:TAIR.::GO:0048579; P:negative regulation of long-day photoperiodism, flowering; IMP:TAIR.::GO:0048577; P:negative regulation of short-day photoperiodism, flowering; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; TAS:TAIR.::GO:0009741; P:response to brassinosteroid stimulus; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009826; P:unidimensional cell growth; IMP:TAIR.
36Q9STM3    1360   REF6_ARATH Lysine-specific demethylase REF6 O...1070.0000000000004     77.4     34     55GO:0005634; C:nucleus; IDA:TAIR.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033169; P:histone H3-K9 demethylation; IMP:TAIR.::GO:0048366; P:leaf development; IMP:TAIR.::GO:0035067; P:negative regulation of histone acetylation; IMP:TAIR.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009741; P:response to brassinosteroid stimulus; IMP:TAIR.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009826; P:unidimensional cell growth; IMP:TAIR.::GO:0010228; P:vegetative to reproductive phase transition of meristem; IMP:TAIR.
37Q23541    1477   KDM5_CAEEL Lysine-specific demethylase rbr-2 ...1440.000000000002     75.1     31     43GO:0005634; C:nucleus; IDA:WormBase.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); IDA:WormBase.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IDA:WormBase.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0040028; P:regulation of vulval development; IMP:WormBase.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
38Q9US53    715   JMJ2_SCHPO Jumonji/ARID domain-containing pro...470.6     37.4     34     55GO:0005634; C:nucleus; IDA:PomBase.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0034648; F:histone demethylase activity (H3-dimethyl-K4 specific); IDA:PomBase.::GO:0051864; F:histone demethylase activity (H3-K36 specific); ISS:PomBase.::GO:0034647; F:histone demethylase activity (H3-trimethyl-K4 specific); IDA:PomBase.
GO:0006338; P:chromatin remodeling; IMP:PomBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:PomBase.
39Q61T02    1482   KDM5_CAEBR Lysine-specific demethylase rbr-2 ...1440.00000000002     71.6     30     43GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0016706; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors; IEA:InterPro.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
40Q1LVC2    1319   JARD2_DANRE Protein Jumonji OS=Danio rerio (Z...1520.056     41.2     22     43GO:0035097; C:histone methyltransferase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0031061; P:negative regulation of histone methylation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051574; P:positive regulation of histone H3-K9 methylation; ISS:UniProtKB.::GO:0048863; P:stem cell differentiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
41Q62315    1234   JARD2_MOUSE Protein Jumonji OS=Mus musculus (...1950.0000000003     68.2     27     42
GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; TAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0001889; P:liver development; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; IMP:MGI.::GO:0031061; P:negative regulation of histone methylation; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0051574; P:positive regulation of histone H3-K9 methylation; IDA:UniProtKB.::GO:0048536; P:spleen development; IMP:MGI.::GO:0048863; P:stem cell differentiation; IMP:UniProtKB.::GO:0048538; P:thymus development; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
42Q5F363    1233   JARD2_CHICK Protein Jumonji OS=Gallus gallus ...1950.0000000003     68.2     26     43GO:0035097; C:histone methyltransferase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0031061; P:negative regulation of histone methylation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0051574; P:positive regulation of histone H3-K9 methylation; ISS:UniProtKB.::GO:0048863; P:stem cell differentiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
43Q10076    582   YANB_SCHPO Zinc finger protein C3H1.11 OS=Sch...570.0000000004     67     49     67GO:0000790; C:nuclear chromatin; NAS:PomBase.
GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IMP:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043619; P:regulation of transcription from RNA polymerase II promoter in response to oxidative stress; IMP:PomBase.
44Q92833    1246   JARD2_HUMAN Protein Jumonji OS=Homo sapiens (...1950.0000000006     67     26     42
GO:0003682; F:chromatin binding; ISS:UniProtKB.
GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0031061; P:negative regulation of histone methylation; ISS:UniProtKB.::GO:0051574; P:positive regulation of histone H3-K9 methylation; ISS:UniProtKB.::GO:0048863; P:stem cell differentiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
45P18738    112   ZG9_XENLA Gastrula zinc finger protein XlCGF9...510.00002     48.9     39     61GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
46P18750    224   ZO61_XENLA Oocyte zinc finger protein XlCOF6....510.042     40     33     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
47P33749    630   MSN4_YEAST Zinc finger protein MSN4 OS=Saccha...540.000000005     63.5     44     63GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0000987; F:core promoter proximal region sequence-specific DNA binding; IDA:SGD.::GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006338; P:chromatin remodeling; IGI:SGD.::GO:0061401; P:positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment; IGI:SGD.::GO:0061402; P:positive regulation of transcription from RNA polymerase II promoter in response to acidity; IMP:SGD.::GO:0061422; P:positive regulation of transcription from RNA polymerase II promoter in response to alkalinity; IGI:SGD.::GO:0061412; P:positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation; IGI:SGD.::GO:0061395; P:positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance; IGI:SGD.::GO:0061410; P:positive regulation of transcription from RNA polymerase II promoter in response to ethanol; IGI:SGD.::GO:0061409; P:positive regulation of transcription from RNA polymerase II promoter in response to freezing; IGI:SGD.::GO:0061406; P:positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation; IGI:SGD.::GO:0061408; P:positive regulation of transcription from RNA polymerase II promoter in response to heat stress; IMP:SGD.::GO:0061407; P:positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide; IMP:SGD.::GO:0061405; P:positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure; IGI:SGD.::GO:0061404; P:positive regulation of transcription from RNA polymerase II promoter in response to increased salt; IGI:SGD.::GO:0061403; P:positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress; IGI:SGD.::GO:0097236; P:positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation; IGI:SGD.::GO:0001302; P:replicative cell aging; IGI:SGD.
48Q96BV0    537   ZN775_HUMAN Zinc finger protein 775 OS=Homo s...480.77     37     35     69GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
49P46974    1380   RSF2_YEAST Respiration factor 2 OS=Saccharomy...630.00000004     60.8     41     60GO:0005634; C:nucleus; IDA:SGD.
GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
50Q96N77    438   ZN641_HUMAN Zinc finger protein 641 OS=Homo s...760.42     37.7     32     41GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
51Q811F1    908   ZBT41_MOUSE Zinc finger and BTB domain-contai...728.2     33.9     32     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
52Q5SVQ8    909   ZBT41_HUMAN Zinc finger and BTB domain-contai...729.1     33.9     32     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
53Q8BZ34    422   ZN641_MOUSE Zinc finger protein 641 OS=Mus mu...740.34     38.1     32     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
54P18740    139   ZO14_XENLA Oocyte zinc finger protein XlCOF14...500.001     43.5     40     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
55Q9NQV7    894   PRDM9_HUMAN Histone-lysine N-methyltransferas...340.36     38.1     50     68GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0018024; F:histone-lysine N-methyltransferase activity; IEA:EC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006311; P:meiotic gene conversion; IDA:MGI.::GO:0010845; P:positive regulation of reciprocal meiotic recombination; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
56Q8BI73    538   ZN775_MOUSE Zinc finger protein 775 OS=Mus mu...610.26     38.5     34     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
57P18722    280   ZG46_XENLA Gastrula zinc finger protein XlCGF...643.7     34.3     34     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
58Q15929    161   ZNF56_HUMAN Putative zinc finger protein 56 O...420.00003     48.9     48     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
59Q04545    1251   TDA9_YEAST Probable transcription factor TDA9...630.0000001     59.7     40     60GO:0005634; C:nucleus; IDA:SGD.
GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
60Q1LZC0    225   ZNF22_BOVIN Zinc finger protein 22 OS=Bos tau...483     34.7     40     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
61Q5R4X5    224   ZNF22_PONAB Zinc finger protein 22 OS=Pongo a...476.9     33.5     40     51
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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