Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR080W
Length:
992
Number of sequences:
5887
Description:
YDR080W VPS41 SGDID:S000002487, Chr IV from 604008-606986, Genome Release 64-1-1, Verified ORF, "Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex; essential for membrane docking and fusion at the Golgi-to-endosome and endosome-to-vacuole stages of protein transport"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P38959    992   VPS41_YEAST Vacuolar protein sorting-associat...9920     2030     100     100GO:0005768; C:endosome; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0030897; C:HOPS complex; IPI:SGD.
GO:0005488; F:binding; IEA:InterPro.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IPI:SGD.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0034727; P:piecemeal microautophagy of nucleus; IMP:SGD.::GO:0035542; P:regulation of SNARE complex assembly; IDA:SGD.::GO:0032889; P:regulation of vacuole fusion, non-autophagic; IDA:SGD.::GO:0006624; P:vacuolar protein processing; IMP:SGD.::GO:0042144; P:vacuole fusion, non-autophagic; IDA:SGD.::GO:0016192; P:vesicle-mediated transport; IMP:SGD.
2P49754    854   VPS41_HUMAN Vacuolar protein sorting-associat...8982e-62     231     25     44GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005798; C:Golgi-associated vesicle; IMP:UniProtKB.::GO:0030897; C:HOPS complex; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048193; P:Golgi vesicle transport; IMP:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
3Q5KU39    853   VPS41_MOUSE Vacuolar protein sorting-associat...8964e-61     228     24     43GO:0005769; C:early endosome; IDA:MGI.::GO:0005770; C:late endosome; IDA:MGI.::GO:0005874; C:microtubule; IDA:MGI.
GO:0008017; F:microtubule binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
4P93231    960   VPS41_SOLLC Vacuolar protein sorting-associat...8942e-59     223     23     43
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
5Q9P7N3    871   VPS41_SCHPO Vacuolar protein sorting-associat...8191e-50     196     25     45GO:0030897; C:HOPS complex; ISS:PomBase.
GO:0005488; F:binding; IEA:InterPro.
GO:0006895; P:Golgi to endosome transport; ISS:PomBase.::GO:0045324; P:late endosome to vacuole transport; ISS:PomBase.::GO:0006623; P:protein targeting to vacuole; ISS:PomBase.::GO:0042144; P:vacuole fusion, non-autophagic; ISS:PomBase.::GO:0048278; P:vesicle docking; ISS:PomBase.
6P93043    980   VPS41_ARATH Vacuolar protein sorting-associat...8855e-50     195     24     41
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009630; P:gravitropism; IMP:TAIR.::GO:0006623; P:protein targeting to vacuole; TAS:TAIR.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
7Q19954    901   VPS41_CAEEL Vacuolar protein sorting-associat...9284e-29     129     21     40GO:0005773; C:vacuole; IC:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006624; P:vacuolar protein processing; IMP:UniProtKB.::GO:0007034; P:vacuolar transport; IMP:UniProtKB.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
8Q618H8    898   VPS41_CAEBR Vacuolar protein sorting-associat...9003e-25     116     21     40GO:0005773; C:vacuole; ISS:GOC.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0006624; P:vacuolar protein processing; ISS:UniProtKB.::GO:0007034; P:vacuolar transport; ISS:UniProtKB.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
9O74184    314   WAT1_SCHPO WD repeat-containing protein wat1 ...890.0002     48.1     33     49GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0031931; C:TORC1 complex; IDA:PomBase.::GO:0031932; C:TORC2 complex; IDA:PomBase.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0000226; P:microtubule cytoskeleton organization; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0006397; P:mRNA processing; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase.
10Q54D08    304   LST8_DICDI Protein LST8 homolog OS=Dictyostel...2240.03     41.2     24     39GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0031932; C:TORC2 complex; IPI:dictyBase.
GO:0007190; P:activation of adenylate cyclase activity; IMP:dictyBase.::GO:0032148; P:activation of protein kinase B activity; IMP:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:dictyBase.::GO:0043520; P:regulation of myosin II filament assembly; IMP:dictyBase.
11Q29RH4    351   THOC3_BOVIN THO complex subunit 3 OS=Bos taur...590.18     38.9     37     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
12Q8VE80    351   THOC3_MOUSE THO complex subunit 3 OS=Mus musc...590.2     38.9     37     56
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
13Q96J01    351   THOC3_HUMAN THO complex subunit 3 OS=Homo sap...590.2     38.9     37     56GO:0000346; C:transcription export complex; IDA:UniProtKB.
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0046784; P:intronless viral mRNA export from host nucleus; IDA:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
14A2RAG5    415   ATG18_ASPNC Autophagy-related protein 18 OS=A...980.31     38.5     32     46GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
15Q5BH53    429   ATG18_EMENI Autophagy-related protein 18 OS=1...660.38     38.1     38     52GO:0005829; C:cytosol; ISS:RefGenome.::GO:0000329; C:fungal-type vacuole membrane; ISS:RefGenome.::GO:0070772; C:PAS complex; ISS:RefGenome.::GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.
GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; ISS:RefGenome.
GO:0016236; P:macroautophagy; ISS:RefGenome.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
16Q5XX13    1052   FBW10_HUMAN F-box/WD repeat-containing protei...870.38     38.5     26     44
17A1DE24    429   ATG18_NEOFI Autophagy-related protein 18 OS=1...660.41     38.1     38     52GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
18Q2U6D5    413   ATG18_ASPOR Autophagy-related protein 18 OS=A...660.45     37.7     38     52GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
19Q4WVD0    436   ATG18_ASPFU Autophagy-related protein 18 OS=A...660.5     37.7     38     52GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
20A6QTX7    400   ATG18_AJECN Autophagy-related protein 18 OS=(...660.6     37.4     36     53GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
21O95170    752   CDRT1_HUMAN CMT1A duplicated region transcrip...870.65     37.7     26     44
22Q5QJC0    388   ATG21_PICAN Autophagy-related protein 21 OS=P...530.78     37     32     64GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
23Q6C044    400   ATG18_YARLI Autophagy-related protein 18 OS=l...770.99     36.6     29     56GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
24A1CBB8    417   ATG18_ASPCL Autophagy-related protein 18 OS=3...661.1     36.6     36     52GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
25Q0CW30    414   ATG18_ASPTN Autophagy-related protein 18 OS=A...541.1     36.6     41     56GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
26P41318    303   LST8_YEAST Target of rapamycin complex subuni...611.3     36.2     26     49GO:0010008; C:endosome membrane; IDA:SGD.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:SGD.::GO:0000139; C:Golgi membrane; IDA:SGD.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:SGD.::GO:0031931; C:TORC1 complex; IPI:SGD.::GO:0031932; C:TORC2 complex; IPI:SGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0030295; F:protein kinase activator activity; IMP:SGD.
GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IMP:SGD.::GO:0031930; P:mitochondria-nucleus signaling pathway; IMP:SGD.::GO:0031929; P:TOR signaling cascade; IMP:SGD.::GO:0006810; P:transport; IMP:SGD.
27Q3LIE5    342   ADPRM_HUMAN Manganese-dependent ADP-ribose/CD...1101.4     36.2     26     43
GO:0047631; F:ADP-ribose diphosphatase activity; IEA:EC.::GO:0047734; F:CDP-glycerol diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
28A1DHW6    689   SCONB_NEOFI Probable E3 ubiquitin ligase comp...842.7     35.4     31     49
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
29Q0U2J8    414   ATG18_PHANO Autophagy-related protein 18 OS=(...542.7     35.4     39     54GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
30Q6PR54    2419   RIF1_MOUSE Telomere-associated protein RIF1 O...1053.2     35.4     25     41GO:0000781; C:chromosome, telomeric region; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0001939; C:female pronucleus; IDA:MGI.::GO:0001940; C:male pronucleus; IDA:MGI.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0019827; P:stem cell maintenance; IMP:MGI.
31A6SJ85    434   ATG18_BOTFB Autophagy-related protein 18 OS=c...733.4     35     34     53GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
records
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