rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P38959 | 992 | VPS41_YEAST Vacuolar protein sorting-associat... | 992 | 0 | 2030 | 100 | 100 | GO:0005768; C:endosome; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0030897; C:HOPS complex; IPI:SGD. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro.::GO:0017112; F:Rab guanyl-nucleotide exchange factor activity; IPI:SGD. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0034727; P:piecemeal microautophagy of nucleus; IMP:SGD.::GO:0035542; P:regulation of SNARE complex assembly; IDA:SGD.::GO:0032889; P:regulation of vacuole fusion, non-autophagic; IDA:SGD.::GO:0006624; P:vacuolar protein processing; IMP:SGD.::GO:0042144; P:vacuole fusion, non-autophagic; IDA:SGD.::GO:0016192; P:vesicle-mediated transport; IMP:SGD. | 2 | P49754 | 854 | VPS41_HUMAN Vacuolar protein sorting-associat... | 898 | 2e-62 | 231 | 25 | 44 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005798; C:Golgi-associated vesicle; IMP:UniProtKB.::GO:0030897; C:HOPS complex; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0048193; P:Golgi vesicle transport; IMP:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro. | 3 | Q5KU39 | 853 | VPS41_MOUSE Vacuolar protein sorting-associat... | 896 | 4e-61 | 228 | 24 | 43 | GO:0005769; C:early endosome; IDA:MGI.::GO:0005770; C:late endosome; IDA:MGI.::GO:0005874; C:microtubule; IDA:MGI. | | | | | | | | | | GO:0008017; F:microtubule binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro. | 4 | P93231 | 960 | VPS41_SOLLC Vacuolar protein sorting-associat... | 894 | 2e-59 | 223 | 23 | 43 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro. | 5 | Q9P7N3 | 871 | VPS41_SCHPO Vacuolar protein sorting-associat... | 819 | 1e-50 | 196 | 25 | 45 | GO:0030897; C:HOPS complex; ISS:PomBase. | | | | | | | | | | GO:0005488; F:binding; IEA:InterPro. | | | | | | | | | | GO:0006895; P:Golgi to endosome transport; ISS:PomBase.::GO:0045324; P:late endosome to vacuole transport; ISS:PomBase.::GO:0006623; P:protein targeting to vacuole; ISS:PomBase.::GO:0042144; P:vacuole fusion, non-autophagic; ISS:PomBase.::GO:0048278; P:vesicle docking; ISS:PomBase. | 6 | P93043 | 980 | VPS41_ARATH Vacuolar protein sorting-associat... | 885 | 5e-50 | 195 | 24 | 41 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0009630; P:gravitropism; IMP:TAIR.::GO:0006623; P:protein targeting to vacuole; TAS:TAIR.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro. | 7 | Q19954 | 901 | VPS41_CAEEL Vacuolar protein sorting-associat... | 928 | 4e-29 | 129 | 21 | 40 | GO:0005773; C:vacuole; IC:UniProtKB. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0006624; P:vacuolar protein processing; IMP:UniProtKB.::GO:0007034; P:vacuolar transport; IMP:UniProtKB.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro. | 8 | Q618H8 | 898 | VPS41_CAEBR Vacuolar protein sorting-associat... | 900 | 3e-25 | 116 | 21 | 40 | GO:0005773; C:vacuole; ISS:GOC. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0006624; P:vacuolar protein processing; ISS:UniProtKB.::GO:0007034; P:vacuolar transport; ISS:UniProtKB.::GO:0016192; P:vesicle-mediated transport; IEA:InterPro. | 9 | O74184 | 314 | WAT1_SCHPO WD repeat-containing protein wat1 ... | 89 | 0.0002 | 48.1 | 33 | 49 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0031931; C:TORC1 complex; IDA:PomBase.::GO:0031932; C:TORC2 complex; IDA:PomBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0000226; P:microtubule cytoskeleton organization; IMP:PomBase.::GO:0000070; P:mitotic sister chromatid segregation; IMP:PomBase.::GO:0006397; P:mRNA processing; IMP:PomBase.::GO:0031929; P:TOR signaling cascade; TAS:PomBase. | 10 | Q54D08 | 304 | LST8_DICDI Protein LST8 homolog OS=Dictyostel... | 224 | 0.03 | 41.2 | 24 | 39 | GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0031932; C:TORC2 complex; IPI:dictyBase. | | | | | | | | | | | | | | | | | | | | GO:0007190; P:activation of adenylate cyclase activity; IMP:dictyBase.::GO:0032148; P:activation of protein kinase B activity; IMP:dictyBase.::GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0043327; P:chemotaxis to cAMP; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:dictyBase.::GO:0043520; P:regulation of myosin II filament assembly; IMP:dictyBase. | 11 | Q29RH4 | 351 | THOC3_BOVIN THO complex subunit 3 OS=Bos taur... | 59 | 0.18 | 38.9 | 37 | 56 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 12 | Q8VE80 | 351 | THOC3_MOUSE THO complex subunit 3 OS=Mus musc... | 59 | 0.2 | 38.9 | 37 | 56 | | | | | | | | | | | GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 13 | Q96J01 | 351 | THOC3_HUMAN THO complex subunit 3 OS=Homo sap... | 59 | 0.2 | 38.9 | 37 | 56 | GO:0000346; C:transcription export complex; IDA:UniProtKB. | | | | | | | | | | GO:0003723; F:RNA binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0046784; P:intronless viral mRNA export from host nucleus; IDA:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. | 14 | A2RAG5 | 415 | ATG18_ASPNC Autophagy-related protein 18 OS=A... | 98 | 0.31 | 38.5 | 32 | 46 | GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 15 | Q5BH53 | 429 | ATG18_EMENI Autophagy-related protein 18 OS=1... | 66 | 0.38 | 38.1 | 38 | 52 | GO:0005829; C:cytosol; ISS:RefGenome.::GO:0000329; C:fungal-type vacuole membrane; ISS:RefGenome.::GO:0070772; C:PAS complex; ISS:RefGenome.::GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; ISS:RefGenome. | | | | | | | | | | GO:0016236; P:macroautophagy; ISS:RefGenome.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 16 | Q5XX13 | 1052 | FBW10_HUMAN F-box/WD repeat-containing protei... | 87 | 0.38 | 38.5 | 26 | 44 | | | | | | | | | | | | | | | | | | | | | | 17 | A1DE24 | 429 | ATG18_NEOFI Autophagy-related protein 18 OS=1... | 66 | 0.41 | 38.1 | 38 | 52 | GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 18 | Q2U6D5 | 413 | ATG18_ASPOR Autophagy-related protein 18 OS=A... | 66 | 0.45 | 37.7 | 38 | 52 | GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 19 | Q4WVD0 | 436 | ATG18_ASPFU Autophagy-related protein 18 OS=A... | 66 | 0.5 | 37.7 | 38 | 52 | GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 20 | A6QTX7 | 400 | ATG18_AJECN Autophagy-related protein 18 OS=(... | 66 | 0.6 | 37.4 | 36 | 53 | GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 21 | O95170 | 752 | CDRT1_HUMAN CMT1A duplicated region transcrip... | 87 | 0.65 | 37.7 | 26 | 44 | | | | | | | | | | | | | | | | | | | | | | 22 | Q5QJC0 | 388 | ATG21_PICAN Autophagy-related protein 21 OS=P... | 53 | 0.78 | 37 | 32 | 64 | GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 23 | Q6C044 | 400 | ATG18_YARLI Autophagy-related protein 18 OS=l... | 77 | 0.99 | 36.6 | 29 | 56 | GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 24 | A1CBB8 | 417 | ATG18_ASPCL Autophagy-related protein 18 OS=3... | 66 | 1.1 | 36.6 | 36 | 52 | GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 25 | Q0CW30 | 414 | ATG18_ASPTN Autophagy-related protein 18 OS=A... | 54 | 1.1 | 36.6 | 41 | 56 | GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 26 | P41318 | 303 | LST8_YEAST Target of rapamycin complex subuni... | 61 | 1.3 | 36.2 | 26 | 49 | GO:0010008; C:endosome membrane; IDA:SGD.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:SGD.::GO:0000139; C:Golgi membrane; IDA:SGD.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:SGD.::GO:0031931; C:TORC1 complex; IPI:SGD.::GO:0031932; C:TORC2 complex; IPI:SGD.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct.::GO:0030295; F:protein kinase activator activity; IMP:SGD. | | | | | | | | | | GO:0030950; P:establishment or maintenance of actin cytoskeleton polarity; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IMP:SGD.::GO:0031930; P:mitochondria-nucleus signaling pathway; IMP:SGD.::GO:0031929; P:TOR signaling cascade; IMP:SGD.::GO:0006810; P:transport; IMP:SGD. | 27 | Q3LIE5 | 342 | ADPRM_HUMAN Manganese-dependent ADP-ribose/CD... | 110 | 1.4 | 36.2 | 26 | 43 | | | | | | | | | | | GO:0047631; F:ADP-ribose diphosphatase activity; IEA:EC.::GO:0047734; F:CDP-glycerol diphosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | | 28 | A1DHW6 | 689 | SCONB_NEOFI Probable E3 ubiquitin ligase comp... | 84 | 2.7 | 35.4 | 31 | 49 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 29 | Q0U2J8 | 414 | ATG18_PHANO Autophagy-related protein 18 OS=(... | 54 | 2.7 | 35.4 | 39 | 54 | GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. | 30 | Q6PR54 | 2419 | RIF1_MOUSE Telomere-associated protein RIF1 O... | 105 | 3.2 | 35.4 | 25 | 41 | GO:0000781; C:chromosome, telomeric region; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0001939; C:female pronucleus; IDA:MGI.::GO:0001940; C:male pronucleus; IDA:MGI.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.::GO:0019827; P:stem cell maintenance; IMP:MGI. | 31 | A6SJ85 | 434 | ATG18_BOTFB Autophagy-related protein 18 OS=c... | 73 | 3.4 | 35 | 34 | 53 | GO:0034045; C:pre-autophagosomal structure membrane; IEA:UniProtKB-SubCell.::GO:0005774; C:vacuolar membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW. |