Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR069C
Length:
926
Number of sequences:
5887
Description:
YDR069C DOA4 SGDID:S000002476, Chr IV from 587719-584939, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin isopeptidase, required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P35123    962   UBP4_MOUSE Ubiquitin carboxyl-terminal hydrol...1782e-21     104     34     49GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0034394; P:protein localization at cell surface; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
32A6QR55    963   UBP4_BOVIN Ubiquitin carboxyl-terminal hydrol...1944e-22     106     34     48GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0034394; P:protein localization at cell surface; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
33Q5RCD3    963   UBP4_PONAB Ubiquitin carboxyl-terminal hydrol...1788e-22     105     34     50GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0034394; P:protein localization at cell surface; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
34Q13107    963   UBP4_HUMAN Ubiquitin carboxyl-terminal hydrol...1784e-22     106     34     50GO:0005764; C:lysosome; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0031685; F:adenosine receptor binding; IPI:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0031397; P:negative regulation of protein ubiquitination; IMP:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0031647; P:regulation of protein stability; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
35P35125    1406   UBP6_HUMAN Ubiquitin carboxyl-terminal hydrol...600.013     43.1     38     58GO:0005764; C:lysosome; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0055037; C:recycling endosome; IDA:UniProtKB.
GO:0005516; F:calmodulin binding; IPI:UniProtKB.::GO:0004197; F:cysteine-type endopeptidase activity; TAS:UniProtKB.::GO:0003676; F:nucleic acid binding; TAS:ProtInc.::GO:0005097; F:Rab GTPase activator activity; IEA:InterPro.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0060627; P:regulation of vesicle-mediated transport; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
36Q8NFA0    1604   UBP32_HUMAN Ubiquitin carboxyl-terminal hydro...600.004     45.1     40     58GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
GO:0016579; P:protein deubiquitination; TAS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
37A6H8I0    506   UBP22_DANRE Ubiquitin carboxyl-terminal hydro...3895e-30     129     29     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
38P39538    1254   UBP12_YEAST Ubiquitin carboxyl-terminal hydro...1663e-16     87.4     37     55GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:SGD.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
39Q9MAQ3    892   UBP11_ARATH Putative ubiquitin carboxyl-termi...1828e-16     85.9     35     50
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
40P36026    717   UBP11_YEAST Ubiquitin carboxyl-terminal hydro...4434e-29     128     28     43
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
41Q5DU02    525   UBP22_MOUSE Ubiquitin carboxyl-terminal hydro...3852e-28     124     28     41
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IC:MGI.
42P0C8Z3    514   UBP22_BOVIN Ubiquitin carboxyl-terminal hydro...3922e-28     124     28     41
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
43Q9UPT9    525   UBP22_HUMAN Ubiquitin carboxyl-terminal hydro...3922e-28     124     28     41GO:0000124; C:SAGA complex; IDA:UniProtKB.
GO:0030374; F:ligand-dependent nuclear receptor transcription coactivator activity; IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0009790; P:embryo development; NAS:UniProtKB.::GO:0016578; P:histone deubiquitination; IDA:UniProtKB.::GO:0043967; P:histone H4 acetylation; IDA:GOC.::GO:0016574; P:histone ubiquitination; IDA:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
44Q70EL3    339   UBP50_HUMAN Inactive ubiquitin carboxyl-termi...3363e-28     121     30     44
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
45Q9C585    871   UBP8_ARATH Ubiquitin carboxyl-terminal hydrol...1731e-17     92     31     51
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
46Q99K46    921   UBP11_MOUSE Ubiquitin carboxyl-terminal hydro...1690.000000000000003     84.3     33     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
47O22207    924   UBP5_ARATH Ubiquitin carboxyl-terminal hydrol...1766e-21     102     35     50
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:TAIR.
48P51784    963   UBP11_HUMAN Ubiquitin carboxyl-terminal hydro...1661e-16     89     34     49GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
49Q9ZSB5    923   UBP10_ARATH Ubiquitin carboxyl-terminal hydro...1743e-18     94     38     52
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
50Q9VVR1    735   NOT_DROME Ubiquitin carboxyl-terminal hydrola...3701e-27     124     28     45GO:0000124; C:SAGA complex; IDA:FlyBase.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:FlyBase.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0007412; P:axon target recognition; IMP:FlyBase.::GO:0021782; P:glial cell development; IMP:FlyBase.::GO:0008347; P:glial cell migration; IMP:FlyBase.::GO:0016578; P:histone deubiquitination; IMP:FlyBase.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IGI:FlyBase.
51Q6GNI6    523   UB22A_XENLA Ubiquitin carboxyl-terminal hydro...3861e-27     121     28     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
52Q93Y01    910   UBP9_ARATH Ubiquitin carboxyl-terminal hydrol...1743e-18     94     37     52
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
53Q9FPS4    859   UBP23_ARATH Ubiquitin carboxyl-terminal hydro...3782e-27     123     28     45
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
54Q6DCJ1    523   UB22B_XENLA Ubiquitin carboxyl-terminal hydro...3863e-27     120     28     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
55Q8CEG8    438   UBP27_MOUSE Ubiquitin carboxyl-terminal hydro...3895e-27     119     28     42
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
56A6NNY8    438   UBP27_HUMAN Ubiquitin carboxyl-terminal hydro...3887e-27     118     27     41
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
57Q70EK9    711   UBP51_HUMAN Ubiquitin carboxyl-terminal hydro...3878e-27     120     30     42
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
58Q9P275    1121   UBP36_HUMAN Ubiquitin carboxyl-terminal hydro...3702e-26     120     27     42GO:0005730; C:nucleolus; IDA:HPA.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
59P50102    471   UBP8_YEAST Ubiquitin carboxyl-terminal hydrol...3853e-26     116     28     45GO:0071819; C:DUBm complex; IDA:SGD.::GO:0000124; C:SAGA complex; IDA:SGD.::GO:0046695; C:SLIK (SAGA-like) complex; IDA:SGD.
GO:0032947; F:protein complex scaffold; IDA:SGD.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016578; P:histone deubiquitination; IMP:SGD.::GO:0051568; P:histone H3-K4 methylation; IMP:SGD.::GO:0034729; P:histone H3-K79 methylation; IMP:SGD.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
60Q61068    526   UBPW_MOUSE Ubiquitin carboxyl-terminal hydrol...3625e-26     117     29     41
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:MGI.
GO:0016579; P:protein deubiquitination; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
61Q7M764    540   U17L2_MOUSE Ubiquitin carboxyl-terminal hydro...3627e-25     113     27     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0031576; P:G2/M transition checkpoint; ISS:UniProtKB.::GO:0031575; P:mitotic cell cycle G1/S transition checkpoint; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
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