Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR063W
Length:
149
Number of sequences:
5887
Description:
YDR063W AIM7 SGDID:S000002470, Chr IV from 578663-579112, Genome Release 64-1-1, Verified ORF, "Protein that interacts with Arp2/3 complex to stimulate actin filament debranching and inhibit actin nucleation; has similarity to Cof1p and also to human glia maturation factor (GMF); null mutant displays elevated mitochondrial genome loss"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1Q12156    149   AIM7_YEAST Protein AIM7 OS=Saccharomyces cere...1491e-104     302     100     100GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0003779; F:actin binding; IEA:InterPro.
GO:0071846; P:actin filament debranching; IDA:SGD.::GO:0034316; P:negative regulation of Arp2/3 complex-mediated actin nucleation; IDA:SGD.
2O13808    141   YE0B_SCHPO Uncharacterized protein C17H9.11 O...1270.000000000008     62.8     29     55GO:0030479; C:actin cortical patch; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0071933; F:Arp2/3 complex binding; IDA:PomBase.
GO:0000147; P:actin cortical patch assembly; IMP:PomBase.::GO:0034316; P:negative regulation of Arp2/3 complex-mediated actin nucleation; IMP:PomBase.
3P86293    143   CADF2_PLAFX Cofilin/actin-depolymerizing fact...1100.000006     46.2     33     54GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003785; F:actin monomer binding; ISS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0060327; P:cytoplasmic actin-based contraction involved in cell motility; ISS:UniProtKB.
4Q8ID92    143   CADF2_PLAF7 Cofilin/actin-depolymerizing fact...1100.000006     46.2     33     54GO:0015629; C:actin cytoskeleton; ISS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003785; F:actin monomer binding; ISS:UniProtKB.
GO:0008154; P:actin polymerization or depolymerization; ISS:GeneDB_Pfalciparum.::GO:0060327; P:cytoplasmic actin-based contraction involved in cell motility; ISS:UniProtKB.
5Q5R6P6    142   GMFB_PONAB Glia maturation factor beta OS=Pon...1350.00002     45.1     29     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
6P60983    142   GMFB_HUMAN Glia maturation factor beta OS=Hom...1350.00002     45.1     29     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008047; F:enzyme activator activity; TAS:ProtInc.::GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.::GO:0004860; F:protein kinase inhibitor activity; TAS:ProtInc.::GO:0004871; F:signal transducer activity; TAS:ProtInc.
GO:0007399; P:nervous system development; TAS:ProtInc.::GO:0006468; P:protein phosphorylation; TAS:ProtInc.
7P60984    142   GMFB_BOVIN Glia maturation factor beta OS=Bos...1350.00002     45.1     29     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
8Q63228    142   GMFB_RAT Glia maturation factor beta OS=Rattu...1350.00002     44.7     29     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
9Q9CQI3    142   GMFB_MOUSE Glia maturation factor beta OS=Mus...1350.00004     44.3     29     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
10Q9ERL7    142   GMFG_MOUSE Glia maturation factor gamma OS=Mu...1060.0001     43.1     31     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
11Q80T18    142   GMFG_RAT Glia maturation factor gamma OS=Ratt...1060.0001     42.7     31     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.::GO:0019207; F:kinase regulator activity; NAS:RGD.
12Q56JZ9    142   GMFG_BOVIN Glia maturation factor gamma OS=Bo...1440.0002     42.4     28     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
13O60234    142   GMFG_HUMAN Glia maturation factor gamma OS=Ho...910.0007     40.8     30     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:InterPro.::GO:0008047; F:enzyme activator activity; TAS:ProtInc.::GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.::GO:0004860; F:protein kinase inhibitor activity; TAS:ProtInc.
GO:0006468; P:protein phosphorylation; TAS:ProtInc.
14Q5G6V9    166   COF2_PIG Cofilin-2 OS=Sus scrofa (Pig). GN=CF...1100.004     38.9     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
15Q9Y281    166   COF2_HUMAN Cofilin-2 OS=Homo sapiens (Human)....1100.004     38.9     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
16Q148F1    166   COF2_BOVIN Cofilin-2 OS=Bos taurus (Bovine). ...1100.004     38.9     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
17P45591    166   COF2_MOUSE Cofilin-2 OS=Mus musculus (Mouse)....1100.005     38.9     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
18P21566    166   COF2_CHICK Cofilin-2 OS=Gallus gallus (Chicke...1100.005     38.9     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
19Q570Y6    140   ADF8_ARATH Actin-depolymerizing factor 8 OS=A...1040.009     37.7     25     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
20Q8SAG3    143   ADF_VITVI Actin-depolymerizing factor OS=Viti...900.026     36.6     29     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
21Q9AY76    145   ADF2_ORYSJ Actin-depolymerizing factor 2 OS=O...800.042     36.2     28     53GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
22Q2QLT8    145   ADF11_ORYSJ Actin-depolymerizing factor 11 OS...890.072     35.4     26     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
23A1RT57    156   RL15_PYRIL 50S ribosomal protein L15P OS=Pyro...280.34     33.5     43     61GO:0015934; C:large ribosomal subunit; IEA:InterPro.
GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
24P46251    139   ADF1_MAIZE Actin-depolymerizing factor 1 OS=Z...1060.53     33.1     23     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
25Q9LQ81    140   ADF10_ARATH Actin-depolymerizing factor 10 OS...1040.56     32.7     24     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
26A4WM07    155   RL15_PYRAR 50S ribosomal protein L15P OS=Pyro...260.6     33.1     46     62GO:0015934; C:large ribosomal subunit; IEA:InterPro.
GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.::GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
GO:0006412; P:translation; IEA:InterPro.
27Q9FVI2    139   ADF1_PETHY Actin-depolymerizing factor 1 OS=P...1090.94     32.3     20     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
28Q03654    590   CEF1_YEAST Pre-mRNA-splicing factor CEF1 OS=S...1511.4     32.3     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000974; C:Prp19 complex; IDA:SGD.::GO:0071006; C:U2-type catalytic step 1 spliceosome; IDA:SGD.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IMP:SGD.
29P30175    139   ADF_LILLO Actin-depolymerizing factor OS=Lili...641.6     31.6     25     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
30Q9FVI1    143   ADF2_PETHY Actin-depolymerizing factor 2 OS=P...1091.7     31.6     21     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
31Q96VU9    143   COFI_PICAD Cofilin OS=(Hansenula polymorpha)....791.9     31.6     30     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016363; C:nuclear matrix; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.
records
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