Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR062W
Length:
561
Number of sequences:
5887
Description:
YDR062W LCB2 SGDID:S000002469, Chr IV from 576474-578159, Genome Release 64-1-1, Verified ORF, "Component of serine palmitoyltransferase, responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40970    561   LCB2_YEAST Serine palmitoyltransferase 2 OS=S...5610     1166     100     100GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IPI:SGD.::GO:0035339; C:SPOTS complex; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IMP:SGD.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0030148; P:sphingolipid biosynthetic process; IMP:SGD.
2P48241    562   LCB2_KLULA Serine palmitoyltransferase 2 OS=1...5540     908     77     88GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IEA:EC.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.
3Q09925    603   LCB2_SCHPO Serine palmitoyltransferase 2 OS=S...5680     560     51     65GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0017059; C:serine C-palmitoyltransferase complex; ISS:PomBase.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; ISS:PomBase.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0030148; P:sphingolipid biosynthetic process; ISS:PomBase.
4P97363    560   SPTC2_MOUSE Serine palmitoyltransferase 2 OS=...5028e-164     485     48     67GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:MGI.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IDA:MGI.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0046511; P:sphinganine biosynthetic process; IDA:MGI.::GO:0006686; P:sphingomyelin biosynthetic process; IMP:MGI.::GO:0046512; P:sphingosine biosynthetic process; IMP:MGI.
5O15270    562   SPTC2_HUMAN Serine palmitoyltransferase 2 OS=...4931e-162     482     48     68GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0017059; C:serine C-palmitoyltransferase complex; IDA:UniProtKB.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IDA:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
6O54694    560   SPTC2_CRIGR Serine palmitoyltransferase 2 OS=...4972e-162     481     48     67GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IEA:EC.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.
7Q54EX5    490   SPTC2_DICDI Serine palmitoyltransferase 2 OS=...4793e-153     455     46     66GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0017059; C:serine C-palmitoyltransferase complex; ISS:dictyBase.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; ISS:dictyBase.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0030148; P:sphingolipid biosynthetic process; ISS:dictyBase.
8Q9NUV7    552   SPTC3_HUMAN Serine palmitoyltransferase 3 OS=...4822e-151     453     46     66GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0017059; C:serine C-palmitoyltransferase complex; IDA:UniProtKB.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IDA:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0046520; P:sphingoid biosynthetic process; IDA:MGI.
9Q8BG54    563   SPTC3_MOUSE Serine palmitoyltransferase 3 OS=...4832e-143     432     45     65GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; IEA:EC.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
10Q5KY23    390   BIOF_GEOKA Putative 8-amino-7-oxononanoate sy...3718e-64     219     32     56
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
11B0K590    395   BIKB_THEPX Putative 8-amino-7-oxononanoate sy...3682e-63     219     32     57
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
12B0KC20    395   BIKB_THEP3 Putative 8-amino-7-oxononanoate sy...3682e-63     218     32     57
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
13Q73KM3    395   BIKB_TREDE Putative 8-amino-7-oxononanoate sy...3687e-63     217     32     55
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
14A7HMM1    395   BIKB_FERNB Putative 8-amino-7-oxononanoate sy...3699e-63     217     34     56
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
15A6TU88    395   BIKB_ALKMQ Putative 8-amino-7-oxononanoate sy...3722e-62     216     34     55
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
16B7ID58    391   BIKB_THEAB Putative 8-amino-7-oxononanoate sy...3683e-62     216     33     55
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
17A6LMP4    391   BIKB_THEM4 Putative 8-amino-7-oxononanoate sy...3683e-62     216     33     56
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
18A8MEX7    395   BIKB_ALKOO Putative 8-amino-7-oxononanoate sy...3691e-61     214     34     54
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
19Q67N86    392   BIKB_SYMTH Putative 8-amino-7-oxononanoate sy...3689e-61     211     34     55
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
20O31777    392   BIKB_BACSU Putative 8-amino-7-oxononanoate sy...3686e-59     207     33     55
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
21A7Z4X1    391   BIKB_BACA2 Putative 8-amino-7-oxononanoate sy...3688e-57     201     32     54
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
22Q8EM07    396   PPAT_OCEIH Putative pyridoxal phosphate-depen...3911e-56     201     32     53
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.
23Q81V80    396   PPAT_BACAN Putative pyridoxal phosphate-depen...3907e-55     196     32     53
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.
24A9BGL0    393   BIKB_PETMO Putative 8-amino-7-oxononanoate sy...3668e-55     196     32     54
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
25A7GSE1    395   BIOF_BACCN Putative 8-amino-7-oxononanoate sy...3649e-55     195     30     54
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
26A8FDG9    392   BIKB_BACP2 Putative 8-amino-7-oxononanoate sy...3681e-54     195     32     54
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
27A3DBD5    388   BIOF_CLOTH Putative 8-amino-7-oxononanoate sy...3682e-54     194     34     53
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
28Q81I05    396   PPAT_BACCR Putative pyridoxal phosphate-depen...3908e-54     193     31     53
GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009058; P:biosynthetic process; IEA:InterPro.
29B5Y9Z4    393   BIKB_COPPD Putative 8-amino-7-oxononanoate sy...3682e-53     192     29     55
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
30B1YMC6    390   BIKB_EXIS2 Putative 8-amino-7-oxononanoate sy...3703e-53     191     32     52
GO:0008710; F:8-amino-7-oxononanoate synthase activity; ISS:UniProtKB.::GO:0008890; F:glycine C-acetyltransferase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; ISS:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; ISS:UniProtKB.
31Q65ML1    379   BIOF_BACLD Putative 8-amino-7-oxononanoate sy...3668e-53     189     33     53
GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
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