UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR062W

Length:

561

Number of sequences:

5887

Description:

YDR062W LCB2 SGDID:S000002469, Chr IV from 576474-578159, Genome Release 64-1-1, Verified ORF, "Component of serine palmitoyltransferase, responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
211	Q8DJ97	391	BIOF_THEEB Putative 8-amino-7-oxononanoate sy...	362	5e-32	130	30	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
212	Q8FJQ2	384	BIOF_ECOL6 8-amino-7-oxononanoate synthase OS...	358	5e-32	130	29	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
213	Q7NPW2	383	BIOF_CHRVO 8-amino-7-oxononanoate synthase OS...	356	6e-32	130	29	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
214	B1LM67	384	BIOF_ECOSM 8-amino-7-oxononanoate synthase OS...	365	6e-32	130	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
215	B7ULX3	384	BIOF_ECO27 8-amino-7-oxononanoate synthase OS...	355	6e-32	130	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
216	B1IXJ2	384	BIOF_ECOLC 8-amino-7-oxononanoate synthase OS...	358	7e-32	130	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
217	A7ZY32	384	BIOF_ECOHS 8-amino-7-oxononanoate synthase OS...	358	7e-32	130	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
218	Q06965	407	HEM0_RHOS4 5-aminolevulinate synthase 2 OS=15...	367	8e-32	130	26	48
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
219	A6T6L6	385	BIOF_KLEP7 8-amino-7-oxononanoate synthase OS...	375	8e-32	130	27	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
220	P26505	405	HEM1_RHIRD 5-aminolevulinate synthase OS=radi...	354	9e-32	130	27	47
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
221	A7MJ02	383	BIOF_CROS8 8-amino-7-oxononanoate synthase OS...	356	1e-31	129	28	45
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
222	P13196	640	HEM1_HUMAN 5-aminolevulinate synthase, nonspe...	456	1e-31	132	27	47	GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0006783; P:heme biosynthetic process; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
223	B5YRL5	384	BIOF_ECO5E 8-amino-7-oxononanoate synthase OS...	358	1e-31	129	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
224	Q8X823	384	BIOF_ECO57 8-amino-7-oxononanoate synthase OS...	358	1e-31	129	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
225	Q6A6M4	653	BIOWF_PROAC Biotin biosynthesis bifunctional ...	371	2e-31	132	29	47
									GO:0042410; F:6-carboxyhexanoate-CoA ligase activity; IEA:EC.::GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
226	A6QLI6	647	HEM1_BOVIN 5-aminolevulinate synthase, nonspe...	449	2e-31	132	25	47	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
227	Q3Z408	384	BIOF_SHISS 8-amino-7-oxononanoate synthase OS...	358	2e-31	129	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
228	Q92403	621	HEM1_AGABI 5-aminolevulinate synthase, mitoch...	383	2e-31	132	28	47	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
229	Q0TJS2	384	BIOF_ECOL5 8-amino-7-oxononanoate synthase OS...	358	2e-31	129	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
230	B7MQM9	384	BIOF_ECO81 8-amino-7-oxononanoate synthase OS...	358	2e-31	129	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
231	Q5R9R9	640	HEM1_PONAB 5-aminolevulinate synthase, nonspe...	439	2e-31	132	27	47	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
232	Q32I45	384	BIOF_SHIDS 8-amino-7-oxononanoate synthase OS...	358	3e-31	128	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
233	B5XZ74	385	BIOF_KLEP3 8-amino-7-oxononanoate synthase OS...	384	3e-31	128	27	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
234	P78698	570	HEM1_KLULA 5-aminolevulinate synthase, mitoch...	381	3e-31	131	28	47	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
235	P12998	384	BIOF_ECOLI 8-amino-7-oxononanoate synthase OS...	358	3e-31	128	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IDA:EcoCyc.::GO:0030170; F:pyridoxal phosphate binding; IDA:UniProtKB.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IMP:EcoCyc.
236	B1X7A6	384	BIOF_ECODH 8-amino-7-oxononanoate synthase OS...	358	3e-31	128	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
237	P09950	548	HEM1_YEAST 5-aminolevulinate synthase, mitoch...	387	4e-31	130	28	47	GO:0005759; C:mitochondrial matrix; IDA:SGD.
									GO:0003870; F:5-aminolevulinate synthase activity; IDA:SGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IMP:SGD.
238	B7LC58	384	BIOF_ECO55 8-amino-7-oxononanoate synthase OS...	358	4e-31	128	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
239	Q6D3C0	385	BIOF_ERWCT 8-amino-7-oxononanoate synthase OS...	365	5e-31	127	27	45
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
240	A1KVF6	380	BIOF_NEIMF Putative 8-amino-7-oxononanoate sy...	355	6e-31	127	26	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
241	Q83S45	384	BIOF_SHIFL 8-amino-7-oxononanoate synthase OS...	358	6e-31	127	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.

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