UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR062W

Length:

561

Number of sequences:

5887

Description:

YDR062W LCB2 SGDID:S000002469, Chr IV from 576474-578159, Genome Release 64-1-1, Verified ORF, "Component of serine palmitoyltransferase, responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
181	Q55FL5	479	SPTC1_DICDI Serine palmitoyltransferase 1 OS=...	247	2e-34	139	33	55	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0017059; C:serine C-palmitoyltransferase complex; ISS:dictyBase.
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; ISS:dictyBase.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0030148; P:sphingolipid biosynthetic process; ISS:dictyBase.
182	Q4UJV4	414	HEM1_RICFE 5-aminolevulinate synthase OS=Rick...	377	2e-34	138	28	50
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
183	B4UCB1	398	BIOF_ANASK 8-amino-7-oxononanoate synthase OS...	361	3e-34	137	31	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
184	P44422	380	BIOF_HAEIN Putative 8-amino-7-oxononanoate sy...	362	1e-33	135	27	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
185	P13195	642	HEM1_RAT 5-aminolevulinate synthase, nonspeci...	438	2e-33	138	26	47	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IDA:RGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0071407; P:cellular response to organic cyclic compound; IEP:RGD.::GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0032025; P:response to cobalt ion; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0034698; P:response to gonadotropin stimulus; IEP:RGD.::GO:0009635; P:response to herbicide; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0010045; P:response to nickel cation; IEP:RGD.::GO:0031667; P:response to nutrient levels; IEP:RGD.::GO:0070541; P:response to platinum ion; IEP:RGD.
186	B1I4F9	384	BIOF_DESAP Putative 8-amino-7-oxononanoate sy...	366	2e-33	134	27	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
187	Q0BUV6	382	BIKB_GRABC Putative 8-amino-7-oxononanoate sy...	351	3e-33	134	28	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
188	Q75DX7	556	HEM1_ASHGO 5-aminolevulinate synthase, mitoch...	392	3e-33	136	27	47	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
189	P43090	582	HEM0_OPSTA 5-aminolevulinate synthase, erythr...	369	3e-33	137	29	49	GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.
190	Q9ZCB8	414	HEM1_RICPR 5-aminolevulinate synthase OS=Rick...	378	4e-33	134	30	51
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
191	Q7RVY5	629	HEM1_NEUCR 5-aminolevulinate synthase, mitoch...	449	4e-33	137	27	45	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
192	A5UJ44	379	BIOF_HAEIG Putative 8-amino-7-oxononanoate sy...	355	4e-33	134	28	51
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
193	Q4QKR3	379	BIOF_HAEI8 Putative 8-amino-7-oxononanoate sy...	355	4e-33	134	28	51
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
194	B7VH15	403	BIOF_VIBSL 8-amino-7-oxononanoate synthase OS...	367	5e-33	134	27	45
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
195	A5UCE4	380	BIOF_HAEIE Putative 8-amino-7-oxononanoate sy...	355	5e-33	133	27	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
196	Q2IF62	397	BIOF_ANADE 8-amino-7-oxononanoate synthase OS...	361	7e-33	133	31	51
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
197	B8IBW2	379	BIKB_METNO Putative 8-amino-7-oxononanoate sy...	365	8e-33	133	29	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
198	A5VXF2	390	BIOF_PSEP1 8-amino-7-oxononanoate synthase OS...	356	8e-33	133	27	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
199	Q87QN5	383	BIOF_VIBPA 8-amino-7-oxononanoate synthase OS...	357	9e-33	133	29	43
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
200	P43091	627	HEM1_OPSTA 5-aminolevulinate synthase, nonspe...	467	9e-33	136	27	48	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
201	Q1REF4	384	BIOF_ECOUT 8-amino-7-oxononanoate synthase OS...	356	9e-33	132	29	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
202	A1A918	384	BIOF_ECOK1 8-amino-7-oxononanoate synthase OS...	356	9e-33	132	29	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
203	B7MGN4	384	BIOF_ECO45 8-amino-7-oxononanoate synthase OS...	356	9e-33	132	29	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
204	A4G5N9	388	BIOF_HERAR 8-amino-7-oxononanoate synthase OS...	362	1e-32	132	28	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
205	B8J637	398	BIOF_ANAD2 8-amino-7-oxononanoate synthase OS...	361	1e-32	132	31	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
206	B7LJY7	384	BIOF_ESCF3 8-amino-7-oxononanoate synthase OS...	356	1e-32	132	29	49
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
207	P38092	648	HEM1_EMENI 5-aminolevulinate synthase, mitoch...	422	1e-32	135	27	44	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
208	A7MX30	383	BIOF_VIBHB 8-amino-7-oxononanoate synthase OS...	398	2e-32	132	27	43
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
209	B4ESU4	387	BIOF_PROMH 8-amino-7-oxononanoate synthase OS...	383	2e-32	132	27	45	GO:0015629; C:actin cytoskeleton; IEA:InterPro.
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0003779; F:actin binding; IEA:InterPro.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.
210	Q6CCW0	563	HEM1_YARLI 5-aminolevulinate synthase, mitoch...	440	3e-32	134	27	44	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
211	Q8DJ97	391	BIOF_THEEB Putative 8-amino-7-oxononanoate sy...	362	5e-32	130	30	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.

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