UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR062W

Length:

561

Number of sequences:

5887

Description:

YDR062W LCB2 SGDID:S000002469, Chr IV from 576474-578159, Genome Release 64-1-1, Verified ORF, "Component of serine palmitoyltransferase, responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
151	B6ESC6	383	BIOF_ALISL 8-amino-7-oxononanoate synthase OS...	362	5e-36	142	29	50
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
152	Q0VMD1	386	BIOF_ALCBS 8-amino-7-oxononanoate synthase OS...	361	6e-36	142	29	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
153	Q2W3L2	392	BIOF_MAGSA Putative 8-amino-7-oxononanoate sy...	361	6e-36	142	29	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
154	Q5R557	587	HEM0_PONAB 5-aminolevulinate synthase, erythr...	365	7e-36	144	30	50	GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.
155	B5YFU5	388	BIOF_THEYD Putative 8-amino-7-oxononanoate sy...	366	1e-35	141	30	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
156	B4TQU0	385	BIOF_SALSV 8-amino-7-oxononanoate synthase OS...	408	1e-35	141	27	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
157	P08680	587	HEM0_MOUSE 5-aminolevulinate synthase, erythr...	365	1e-35	144	30	50	GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006879; P:cellular iron ion homeostasis; IMP:MGI.::GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.::GO:0006783; P:heme biosynthetic process; IMP:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; IMP:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.
158	Q3ZC31	587	HEM0_BOVIN 5-aminolevulinate synthase, erythr...	393	1e-35	144	30	47	GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.
159	P43089	409	HEM1_PARDP 5-aminolevulinate synthase OS=Para...	374	2e-35	141	29	47
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
160	C4LK80	720	BIOWF_CORK4 Biotin biosynthesis bifunctional ...	390	2e-35	145	29	46
									GO:0042410; F:6-carboxyhexanoate-CoA ligase activity; IEA:EC.::GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
161	A9HJ57	398	BIKB_GLUDA Putative 8-amino-7-oxononanoate sy...	362	2e-35	141	28	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
162	Q9XT75	582	HEM0_DELLE 5-aminolevulinate synthase, erythr...	381	2e-35	143	29	49	GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.
163	B5FP62	385	BIOF_SALDC 8-amino-7-oxononanoate synthase OS...	408	2e-35	140	27	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
164	Q04512	407	HEM1_RHOS4 5-aminolevulinate synthase 1 OS=15...	355	3e-35	140	31	49
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
165	Q92G23	414	HEM1_RICCN 5-aminolevulinate synthase OS=Rick...	379	4e-35	140	28	50
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
166	A7HP29	389	BIOF_PARL1 Putative 8-amino-7-oxononanoate sy...	356	4e-35	140	31	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
167	Q2Y9Y8	396	BIOF_NITMU 8-amino-7-oxononanoate synthase OS...	361	4e-35	140	28	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
168	Q7WH76	399	BIOF_BORBR Putative 8-amino-7-oxononanoate sy...	364	4e-35	140	28	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
169	P22557	587	HEM0_HUMAN 5-aminolevulinate synthase, erythr...	365	4e-35	142	30	50	GO:0005743; C:mitochondrial inner membrane; IDA:UniProtKB.::GO:0005759; C:mitochondrial matrix; TAS:Reactome.
									GO:0003870; F:5-aminolevulinate synthase activity; IDA:UniProtKB.::GO:0050662; F:coenzyme binding; ISS:UniProtKB.::GO:0016594; F:glycine binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006879; P:cellular iron ion homeostasis; ISS:UniProtKB.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; ISS:UniProtKB.::GO:0032364; P:oxygen homeostasis; NAS:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
170	P18079	409	HEM1_RHOCB 5-aminolevulinate synthase OS=Rhod...	355	5e-35	140	30	48
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
171	Q9YHT4	583	HEM0_DANRE 5-aminolevulinate synthase, erythr...	441	5e-35	142	27	47	GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0035162; P:embryonic hemopoiesis; IMP:ZFIN.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.
172	Q0AE73	387	BIOF_NITEC 8-amino-7-oxononanoate synthase OS...	356	6e-35	139	29	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
173	A9MJE5	385	BIOF_SALAR 8-amino-7-oxononanoate synthase OS...	409	6e-35	139	27	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
174	Q7VL09	387	BIKB_HAEDU Putative 8-amino-7-oxononanoate sy...	366	6e-35	139	28	52
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0008890; F:glycine C-acetyltransferase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
175	Q63147	587	HEM0_RAT 5-aminolevulinate synthase, erythroi...	365	8e-35	141	30	50	GO:0005743; C:mitochondrial inner membrane; ISS:UniProtKB.::GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; ISS:UniProtKB.::GO:0050662; F:coenzyme binding; IDA:RGD.::GO:0016594; F:glycine binding; IDA:RGD.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0007565; P:female pregnancy; IEP:RGD.::GO:0006783; P:heme biosynthetic process; ISS:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; ISS:UniProtKB.::GO:0007595; P:lactation; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.::GO:0010288; P:response to lead ion; IEP:RGD.
176	Q2SBD5	396	BIOF_HAHCH 8-amino-7-oxononanoate synthase OS...	352	8e-35	139	29	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
177	B4SZJ8	385	BIOF_SALNS 8-amino-7-oxononanoate synthase OS...	409	9e-35	139	27	47
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
178	Q7VWP1	397	BIOF_BORPE Putative 8-amino-7-oxononanoate sy...	360	1e-34	138	29	48
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
179	Q7N6Q6	383	BIOF_PHOLL 8-amino-7-oxononanoate synthase OS...	358	1e-34	138	29	46
									GO:0008710; F:8-amino-7-oxononanoate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0009102; P:biotin biosynthetic process; IEA:UniProtKB-KW.
180	Q6FXE3	530	HEM1_CANGA 5-aminolevulinate synthase, mitoch...	387	1e-34	140	29	48	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0003870; F:5-aminolevulinate synthase activity; IEA:EC.::GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
181	Q55FL5	479	SPTC1_DICDI Serine palmitoyltransferase 1 OS=...	247	2e-34	139	33	55	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0017059; C:serine C-palmitoyltransferase complex; ISS:dictyBase.
									GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.::GO:0004758; F:serine C-palmitoyltransferase activity; ISS:dictyBase.::GO:0016769; F:transferase activity, transferring nitrogenous groups; IEA:InterPro.
									GO:0030148; P:sphingolipid biosynthetic process; ISS:dictyBase.

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