UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR059C

Length:

148

Number of sequences:

5887

Description:

YDR059C UBC5 SGDID:S000002466, Chr IV from 569633-569234,569770-569724, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived, abnormal, or excess proteins, including histone H3; central component of the cellular stress response; expression is heat inducible"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
301	Q7M767	145	UB2V2_RAT Ubiquitin-conjugating enzyme E2 var...	103	0.0001	43.1	29	46
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
									GO:0043524; P:negative regulation of neuron apoptotic process; IMP:RGD.::GO:0045739; P:positive regulation of DNA repair; IMP:RGD.::GO:0010976; P:positive regulation of neuron projection development; IMP:RGD.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:RGD.::GO:0051965; P:positive regulation of synapse assembly; IMP:RGD.
302	Q13404	147	UB2V1_HUMAN Ubiquitin-conjugating enzyme E2 v...	85	0.0001	42.7	29	46	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0035370; C:UBC13-UEV1A complex; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0030154; P:cell differentiation; NAS:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:HGNC.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:HGNC.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0006282; P:regulation of DNA repair; TAS:ProtInc.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
303	Q3SZ52	147	UB2V1_BOVIN Ubiquitin-conjugating enzyme E2 v...	85	0.0001	42.7	29	46	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
									GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
304	Q9D2M8	145	UB2V2_MOUSE Ubiquitin-conjugating enzyme E2 v...	103	0.0001	42.7	28	46
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
305	Q5F3Z3	144	UB2V2_CHICK Ubiquitin-conjugating enzyme E2 v...	103	0.0003	42	29	45
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
306	Q5R6C9	145	UB2V2_PONAB Ubiquitin-conjugating enzyme E2 v...	103	0.0003	42	29	45
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
307	Q15819	145	UB2V2_HUMAN Ubiquitin-conjugating enzyme E2 v...	103	0.0003	42	29	45	GO:0005737; C:cytoplasm; TAS:HGNC.::GO:0005634; C:nucleus; IDA:HGNC.::GO:0031372; C:UBC13-MMS2 complex; IDA:HGNC.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0000729; P:DNA double-strand break processing; IMP:HGNC.::GO:0000209; P:protein polyubiquitination; TAS:ProtInc.::GO:0006282; P:regulation of DNA repair; TAS:ProtInc.
308	Q3SZ43	145	UB2V2_BOVIN Ubiquitin-conjugating enzyme E2 v...	103	0.0003	42	29	45
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
309	Q7TSS2	422	UB2Q1_MOUSE Ubiquitin-conjugating enzyme E2 Q...	129	0.0005	42.4	24	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
310	Q7Z7E8	422	UB2Q1_HUMAN Ubiquitin-conjugating enzyme E2 Q...	129	0.0005	42.4	24	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
311	A0PJN4	161	U2QL1_MOUSE Ubiquitin-conjugating enzyme E2Q-...	117	0.0006	41.2	23	43
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
312	Q9VM35	306	U2QL1_DROME Ubiquitin-conjugating enzyme E2Q-...	124	0.0006	42	27	47
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
313	A1L167	161	U2QL1_HUMAN Ubiquitin-conjugating enzyme E2Q-...	117	0.002	40	23	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
314	Q9CZY3	147	UB2V1_MOUSE Ubiquitin-conjugating enzyme E2 v...	56	0.002	39.7	30	46	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
									GO:0042275; P:error-free postreplication DNA repair; IGI:MGI.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
315	Q5R4Z6	147	UB2V1_PONAB Ubiquitin-conjugating enzyme E2 v...	103	0.002	39.3	29	44	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
									GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
316	Q7ZYP0	145	UB2V2_XENLA Ubiquitin-conjugating enzyme E2 v...	52	0.003	38.9	35	48
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
317	Q7ZYX1	293	AKTIP_DANRE AKT-interacting protein OS=Danio ...	89	0.004	39.7	30	51	GO:0070695; C:FHF complex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0007032; P:endosome organization; ISS:UniProtKB.::GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.::GO:0007040; P:lysosome organization; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
318	B5X1G6	297	AKTIP_SALSA AKT-interacting protein OS=Salmo ...	89	0.025	37.4	28	51	GO:0070695; C:FHF complex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0007032; P:endosome organization; ISS:UniProtKB.::GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.::GO:0007040; P:lysosome organization; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
319	A1ZBR5	266	AKTP2_DROME Protein crossbronx-like OS=Drosop...	75	0.063	36.2	32	47
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
320	B4QEJ9	188	AKTP2_DROSI Protein crossbronx-like OS=Drosop...	81	0.18	34.7	30	44
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
321	Q28IA3	292	AKTIP_XENTR AKT-interacting protein OS=Xenopu...	89	0.19	34.7	26	49	GO:0070695; C:FHF complex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0007032; P:endosome organization; ISS:UniProtKB.::GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.::GO:0007040; P:lysosome organization; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
322	Q498F8	293	AKTPA_XENLA AKT-interacting protein homolog A...	89	0.21	34.7	26	49	GO:0070695; C:FHF complex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0007032; P:endosome organization; ISS:UniProtKB.::GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.::GO:0007040; P:lysosome organization; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
323	B4HPU1	266	AKTP2_DROSE Protein crossbronx-like OS=Drosop...	114	0.23	34.7	29	43
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
324	Q64362	292	AKTIP_MOUSE AKT-interacting protein OS=Mus mu...	89	0.27	34.3	26	49	GO:0070695; C:FHF complex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0007032; P:endosome organization; ISS:UniProtKB.::GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.::GO:0007040; P:lysosome organization; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
325	Q5FVH4	292	AKTIP_RAT AKT-interacting protein OS=Rattus n...	89	0.29	34.3	26	49	GO:0070695; C:FHF complex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0007032; P:endosome organization; ISS:UniProtKB.::GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.::GO:0007040; P:lysosome organization; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
326	Q5XGV8	292	AKTPB_XENLA AKT-interacting protein homolog B...	89	0.29	34.3	26	49	GO:0070695; C:FHF complex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0007032; P:endosome organization; ISS:UniProtKB.::GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.::GO:0007040; P:lysosome organization; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
327	Q4R5E1	292	AKTIP_MACFA AKT-interacting protein OS=Macaca...	89	0.32	34.3	26	49	GO:0070695; C:FHF complex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0007032; P:endosome organization; ISS:UniProtKB.::GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.::GO:0007040; P:lysosome organization; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
328	Q9H8T0	292	AKTIP_HUMAN AKT-interacting protein OS=Homo s...	89	0.32	34.3	26	49	GO:0070695; C:FHF complex; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:MGI.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.::GO:0007032; P:endosome organization; IMP:UniProtKB.::GO:0008333; P:endosome to lysosome transport; IMP:UniProtKB.::GO:0007040; P:lysosome organization; IMP:UniProtKB.::GO:0032092; P:positive regulation of protein binding; IDA:MGI.::GO:0001934; P:positive regulation of protein phosphorylation; IDA:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
329	Q5RE48	293	AKTIP_PONAB AKT-interacting protein OS=Pongo ...	89	0.33	33.9	26	49	GO:0070695; C:FHF complex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0007032; P:endosome organization; ISS:UniProtKB.::GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.::GO:0007040; P:lysosome organization; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.
330	B4MRW2	273	AKTP2_DROWI Protein crossbronx-like OS=Drosop...	51	0.37	33.9	41	51
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
331	Q5ZJJ5	293	AKTIP_CHICK AKT-interacting protein OS=Gallus...	89	0.61	33.1	26	48	GO:0070695; C:FHF complex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
									GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0007032; P:endosome organization; ISS:UniProtKB.::GO:0008333; P:endosome to lysosome transport; ISS:UniProtKB.::GO:0007040; P:lysosome organization; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.

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