UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR059C

Length:

148

Number of sequences:

5887

Description:

YDR059C UBC5 SGDID:S000002466, Chr IV from 569633-569234,569770-569724, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived, abnormal, or excess proteins, including histone H3; central component of the cellular stress response; expression is heat inducible"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
151	A5PJC4	153	UB2L6_BOVIN Ubiquitin/ISG15-conjugating enzym...	153	3e-27	104	37	56
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
152	P40984	157	UBC9_SCHPO SUMO-conjugating enzyme ubc9 OS=Sc...	149	2e-26	103	36	54	GO:0005829; C:cytosol; IDA:PomBase.::GO:0000792; C:heterochromatin; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0019789; F:SUMO ligase activity; IPI:PomBase.
									GO:0000075; P:cell cycle checkpoint; IMP:PomBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016925; P:protein sumoylation; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.
153	Q86IZ3	149	UBCX_DICDI Ubiquitin-conjugating enzyme E2 pe...	120	3e-26	102	43	59	GO:0005777; C:peroxisome; ISS:dictyBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
									GO:0016558; P:protein import into peroxisome matrix; ISS:dictyBase.
154	Q28CQ4	158	UBC9_XENTR SUMO-conjugating enzyme UBC9 OS=Xe...	149	3e-26	102	36	54	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
155	P63282	158	UBC9_XENLA SUMO-conjugating enzyme UBC9 OS=Xe...	149	3e-26	102	36	54	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
156	Q2EF73	158	UBC9_SPETR SUMO-conjugating enzyme UBC9 OS=(I...	149	3e-26	102	36	54	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
157	P63281	158	UBC9_RAT SUMO-conjugating enzyme UBC9 OS=Ratt...	149	3e-26	102	36	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0030425; C:dendrite; IDA:RGD.::GO:0001650; C:fibrillar center; IDA:RGD.::GO:0045202; C:synapse; IDA:RGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043425; F:bHLH transcription factor binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IPI:RGD.::GO:0019789; F:SUMO ligase activity; IDA:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:RGD.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0033145; P:positive regulation of intracellular steroid hormone receptor signaling pathway; IDA:RGD.::GO:0051091; P:positive regulation of sequence-specific DNA binding transcription factor activity; IDA:RGD.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:RGD.::GO:0016925; P:protein sumoylation; IDA:RGD.::GO:0010469; P:regulation of receptor activity; IDA:RGD.
158	P63280	158	UBC9_MOUSE SUMO-conjugating enzyme UBC9 OS=Mu...	149	3e-26	102	36	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043398; F:HLH domain binding; IPI:UniProtKB.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.
159	P63279	158	UBC9_HUMAN SUMO-conjugating enzyme UBC9 OS=Ho...	149	3e-26	102	36	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016605; C:PML body; IDA:UniProtKB.::GO:0000795; C:synaptonemal complex; TAS:ProtInc.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:BHF-UCL.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0016925; P:protein sumoylation; IDA:BHF-UCL.
160	P63283	158	UBC9_CHICK SUMO-conjugating enzyme UBC9 OS=Ga...	149	3e-26	102	36	54
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
161	O14933	153	UB2L6_HUMAN Ubiquitin/ISG15-conjugating enzym...	150	4e-26	101	36	55	GO:0005829; C:cytosol; TAS:Reactome.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; TAS:ProtInc.
									GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.
162	Q9W6H5	158	UBC9A_DANRE SUMO-conjugating enzyme UBC9-A OS...	149	5e-26	101	35	55	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019789; F:SUMO ligase activity; IMP:ZFIN.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0016925; P:protein sumoylation; IMP:ZFIN.::GO:0007088; P:regulation of mitosis; IMP:ZFIN.
163	P28263	218	UBC8_YEAST Ubiquitin-conjugating enzyme E2-24...	149	6e-26	102	38	55	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.
									GO:0045721; P:negative regulation of gluconeogenesis; IMP:SGD.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IMP:SGD.::GO:0006513; P:protein monoubiquitination; TAS:SGD.::GO:0000209; P:protein polyubiquitination; TAS:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:SGD.
164	C3Z724	213	UBE2S_BRAFL Ubiquitin-conjugating enzyme E2 S...	143	6e-26	102	36	52	GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
									GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.::GO:0010994; P:free ubiquitin chain polymerization; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.
165	Q9DDJ0	157	UBC9B_DANRE SUMO-conjugating enzyme UBC9-B OS...	149	8e-26	101	35	54	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
166	Q9Y818	167	UBC15_SCHPO Ubiquitin-conjugating enzyme E2 1...	148	9e-26	101	31	57	GO:0005634; C:nucleus; ISS:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
									GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.
167	P50623	157	UBC9_YEAST SUMO-conjugating enzyme UBC9 OS=Sa...	150	1e-25	100	37	55	GO:0000794; C:condensed nuclear chromosome; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019789; F:SUMO ligase activity; IDA:SGD.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0000022; P:mitotic spindle elongation; IMP:SGD.::GO:0016925; P:protein sumoylation; IMP:SGD.
168	P42748	187	UBC4_ARATH Ubiquitin-conjugating enzyme E2 4 ...	123	1e-25	101	41	55
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
169	O00102	166	UBC7_SCHPO Ubiquitin-conjugating enzyme E2-18...	155	2e-25	100	29	53	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0000151; C:ubiquitin ligase complex; ISS:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.
									GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.::GO:0030433; P:ER-associated protein catabolic process; IMP:PomBase.::GO:0010620; P:negative regulation of transcription by transcription factor catabolism; IMP:PomBase.
170	P42749	185	UBC5_ARATH Ubiquitin-conjugating enzyme E2 5 ...	123	2e-25	100	41	55	GO:0005829; C:cytosol; IDA:TAIR.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
171	Q4V8J2	153	UB2L6_RAT Ubiquitin/ISG15-conjugating enzyme ...	150	3e-25	99.8	36	56
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
172	Q95017	166	UBC9_CAEEL SUMO-conjugating enzyme UBC9 OS=Ca...	153	5e-25	99.4	33	56
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0001085; F:RNA polymerase II transcription factor binding; IPI:WormBase.::GO:0032093; F:SAM domain binding; IPI:WormBase.::GO:0019789; F:SUMO ligase activity; IDA:WormBase.
									GO:0009952; P:anterior/posterior pattern specification; IMP:WormBase.::GO:0033554; P:cellular response to stress; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:WormBase.::GO:0040027; P:negative regulation of vulval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0043282; P:pharyngeal muscle development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0016925; P:protein sumoylation; IDA:WormBase.::GO:0032880; P:regulation of protein localization; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
173	Q9VSF3	181	UBC12_DROME NEDD8-conjugating enzyme Ubc12 OS...	144	5e-25	99.8	33	60
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019788; F:NEDD8 ligase activity; ISS:UniProtKB.::GO:0018169; F:ribosomal S6-glutamic acid ligase activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
									GO:0045879; P:negative regulation of smoothened signaling pathway; IMP:FlyBase.::GO:0045116; P:protein neddylation; ISS:UniProtKB.
174	Q5UQC9	158	UBC1_MIMIV Probable ubiquitin-conjugating enz...	150	6e-25	99	35	55
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
175	B4MA02	208	UBE2S_DROVI Ubiquitin-conjugating enzyme E2 S...	143	7e-25	99.8	36	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
									GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.
176	B4JKB7	208	UBE2S_DROGR Ubiquitin-conjugating enzyme E2 S...	143	9e-25	99.8	36	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
									GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.
177	Q9VX25	209	UBE2S_DROME Ubiquitin-conjugating enzyme E2 S...	143	2e-24	99	34	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
									GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; IMP:UniProtKB.
178	B4R6G1	209	UBE2S_DROSI Ubiquitin-conjugating enzyme E2 S...	143	2e-24	99	34	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
									GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.
179	B4IF39	209	UBE2S_DROSE Ubiquitin-conjugating enzyme E2 S...	143	2e-24	99	34	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
									GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.
180	B4L7V4	206	UBE2S_DROMO Ubiquitin-conjugating enzyme E2 S...	143	2e-24	98.6	35	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
									GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.
181	Q6Y1Z4	158	UBC9_PAGMA SUMO-conjugating enzyme UBC9 OS=Pa...	149	3e-24	97.4	34	54	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.

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