UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YDR054C

Length:

295

Number of sequences:

5887

Description:

YDR054C CDC34 SGDID:S000002461, Chr IV from 562327-561440, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-conjugating enzyme (E2) and catalytic subunit of SCF ubiquitin-protein ligase complex (together with Skp1p, Rbx1p, Cdc53p, and an F-box protein) that regulates cell cycle progression by targeting key substrates for degradation"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P14682	295	UBC3_YEAST Ubiquitin-conjugating enzyme E2-34...	295	0	597	100	100	GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IDA:SGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.
									GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; TAS:SGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:SGD.::GO:0051865; P:protein autoubiquitination; IDA:SGD.::GO:0000209; P:protein polyubiquitination; IDA:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.
2	P42747	167	UBC14_ARATH Ubiquitin-conjugating enzyme E2 1...	150	4e-42	148	47	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
3	Q42541	166	UBC13_ARATH Ubiquitin-conjugating enzyme E2 1...	148	1e-40	144	47	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
4	Q42540	166	UBC7_ARATH Ubiquitin-conjugating enzyme E2 7 ...	148	2e-40	144	47	68
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
									GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
5	P49427	236	UB2R1_HUMAN Ubiquitin-conjugating enzyme E2 R...	231	6e-40	145	34	59	GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; NAS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
									GO:0006270; P:DNA-dependent DNA replication initiation; NAS:UniProtKB.::GO:0000082; P:G1/S transition of mitotic cell cycle; NAS:UniProtKB.::GO:0043951; P:negative regulation of cAMP-mediated signaling; IDA:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
6	Q8CFI2	235	UB2R1_MOUSE Ubiquitin-conjugating enzyme E2 R...	214	1e-39	144	35	61	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.
7	Q29503	238	UB2R2_RABIT Ubiquitin-conjugating enzyme E2 R...	199	6e-39	142	36	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
									GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.
8	Q6ZWZ2	238	UB2R2_MOUSE Ubiquitin-conjugating enzyme E2 R...	199	6e-39	142	36	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
									GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.
9	Q712K3	238	UB2R2_HUMAN Ubiquitin-conjugating enzyme E2 R...	199	6e-39	142	36	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
									GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0006513; P:protein monoubiquitination; IDA:UniProtKB.
10	Q9Y818	167	UBC15_SCHPO Ubiquitin-conjugating enzyme E2 1...	153	1e-38	139	46	69	GO:0005634; C:nucleus; ISS:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
									GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.
11	P25868	168	UBC7_WHEAT Ubiquitin-conjugating enzyme E2 7 ...	142	2e-38	139	45	69
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
12	P34477	164	UBC7_CAEEL Probable ubiquitin-conjugating enz...	164	3e-38	138	43	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
13	Q17QG5	165	UB2G2_BOVIN Ubiquitin-conjugating enzyme E2 G...	164	1e-37	137	45	65
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
									GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
14	Q5RF84	165	UB2G2_PONAB Ubiquitin-conjugating enzyme E2 G...	164	1e-37	137	45	65
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
									GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
15	P60605	165	UB2G2_MOUSE Ubiquitin-conjugating enzyme E2 G...	164	1e-37	137	45	65	GO:0005829; C:cytosol; IDA:MGI.::GO:0005783; C:endoplasmic reticulum; IDA:MGI.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
									GO:0030433; P:ER-associated protein catabolic process; IDA:MGI.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
16	P60604	165	UB2G2_HUMAN Ubiquitin-conjugating enzyme E2 G...	164	1e-37	137	45	65	GO:0005829; C:cytosol; IDA:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
									GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
17	Q02159	165	UBC7_YEAST Ubiquitin-conjugating enzyme E2 7 ...	162	6e-37	135	41	65	GO:0005789; C:endoplasmic reticulum membrane; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.
									GO:0006333; P:chromatin assembly or disassembly; IMP:SGD.::GO:0030433; P:ER-associated protein catabolic process; IDA:SGD.::GO:0031505; P:fungal-type cell wall organization; IGI:SGD.::GO:0046686; P:response to cadmium ion; IEA:UniProtKB-KW.
18	P62255	170	UB2G1_RAT Ubiquitin-conjugating enzyme E2 G1 ...	165	2e-36	134	42	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
									GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:RGD.
19	P62254	170	UB2G1_MOUSE Ubiquitin-conjugating enzyme E2 G...	165	2e-36	134	42	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
									GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
20	P62253	170	UB2G1_HUMAN Ubiquitin-conjugating enzyme E2 G...	165	2e-36	134	42	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
									GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:ProtInc.
21	P0C8G3	218	UBC_ASFK5 Ubiquitin-conjugating enzyme E2 OS=...	166	3e-36	134	43	62
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
22	Q4R5Y8	170	UB2G1_MACFA Ubiquitin-conjugating enzyme E2 G...	165	1e-35	131	41	65
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
									GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
23	P0C8G4	217	UBC_ASFP4 Ubiquitin-conjugating enzyme E2 OS=...	166	2e-35	132	42	66
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
24	P27949	215	UBC_ASFB7 Ubiquitin-conjugating enzyme E2 OS=...	166	4e-35	131	43	65
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
25	P25869	213	UBC_ASFM2 Ubiquitin-conjugating enzyme E2 OS=...	166	9e-35	130	43	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
26	P0C8G5	221	UBC_ASFWA Ubiquitin-conjugating enzyme E2 OS=...	166	2e-33	127	42	63
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
27	O00102	166	UBC7_SCHPO Ubiquitin-conjugating enzyme E2-18...	163	4e-33	124	40	61	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0000151; C:ubiquitin ligase complex; ISS:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.
									GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.::GO:0030433; P:ER-associated protein catabolic process; IMP:PomBase.::GO:0010620; P:negative regulation of transcription by transcription factor catabolism; IMP:PomBase.
28	Q8SSK3	216	Y1A1_ENCCU Probable ubiquitin-conjugating enz...	128	1e-30	119	44	62
									GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
29	Q58FS2	151	UBC2_TRIHA Ubiquitin-conjugating enzyme E2 2 ...	166	2e-27	109	38	55	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
30	P78717	151	UBC2_NECHA Ubiquitin-conjugating enzyme E2 2 ...	166	5e-27	108	37	55	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
									GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
31	P35130	152	UBC2_MEDSA Ubiquitin-conjugating enzyme E2 2 ...	163	1e-26	107	38	55
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.

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