Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR054C
Length:
295
Number of sequences:
5887
Description:
YDR054C CDC34 SGDID:S000002461, Chr IV from 562327-561440, Genome Release 64-1-1, reverse complement, Verified ORF, "Ubiquitin-conjugating enzyme (E2) and catalytic subunit of SCF ubiquitin-protein ligase complex (together with Skp1p, Rbx1p, Cdc53p, and an F-box protein) that regulates cell cycle progression by targeting key substrates for degradation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151Q96LR5    201   UB2E2_HUMAN Ubiquitin-conjugating enzyme E2 E...1660.000000000000006     75.1     30     47GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042296; F:ISG15 ligase activity; IDA:HGNC.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0032020; P:ISG15-protein conjugation; IDA:HGNC.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
152P52483    207   UB2E3_MOUSE Ubiquitin-conjugating enzyme E2 E...1290.000000000000006     75.1     32     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
153Q969T4    207   UB2E3_HUMAN Ubiquitin-conjugating enzyme E2 E...1290.000000000000006     75.1     32     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
154Q2T9X7    207   UB2E3_BOVIN Ubiquitin-conjugating enzyme E2 E...1290.000000000000006     75.1     32     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0040008; P:regulation of growth; IEA:UniProtKB-KW.
155A5PJC4    153   UB2L6_BOVIN Ubiquitin/ISG15-conjugating enzym...1460.000000000000007     73.9     29     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
156O13685    148   UBC13_SCHPO Ubiquitin-conjugating enzyme E2 1...1050.000000000000007     73.9     35     54GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IDA:PomBase.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0071479; P:cellular response to ionizing radiation; IDA:PomBase.::GO:0006301; P:postreplication repair; IMP:PomBase.::GO:0070534; P:protein K63-linked ubiquitination; IDA:PomBase.
157P52485    232   UBCD2_DROME Ubiquitin-conjugating enzyme E2-2...1290.000000000000009     75.1     31     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:FlyBase.
GO:0019915; P:lipid storage; IDA:FlyBase.
158O74549    177   UBC12_SCHPO NEDD8-conjugating enzyme ubc12 OS...1140.00000000000001     73.9     31     54GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019788; F:NEDD8 ligase activity; IC:PomBase.
GO:0045116; P:protein neddylation; ISS:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IGI:PomBase.
159P21734    215   UBC1_YEAST Ubiquitin-conjugating enzyme E2 1 ...1390.00000000000001     74.7     31     50GO:0000502; C:proteasome complex; IPI:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.
GO:0006897; P:endocytosis; TAS:SGD.::GO:0030433; P:ER-associated protein catabolic process; IMP:SGD.::GO:0006513; P:protein monoubiquitination; TAS:SGD.::GO:0000209; P:protein polyubiquitination; TAS:SGD.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IMP:SGD.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0009847; P:spore germination; TAS:SGD.::GO:0016050; P:vesicle organization; IMP:SGD.
160Q9CQ37    204   UBE2T_MOUSE Ubiquitin-conjugating enzyme E2 T...1260.00000000000001     74.3     32     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0044314; P:protein K27-linked ubiquitination; ISS:UniProtKB.::GO:0035519; P:protein K29-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.
161Q86K32    154   UBE2N_DICDI Probable ubiquitin-conjugating en...1100.00000000000002     73.2     34     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
162Q32LD2    195   UBE2T_BOVIN Ubiquitin-conjugating enzyme E2 T...1060.00000000000002     73.9     32     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0044314; P:protein K27-linked ubiquitination; ISS:UniProtKB.::GO:0035519; P:protein K29-linked ubiquitination; ISS:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.
163Q94490    148   UBCB_DICDI Ubiquitin conjugating enzyme E2 B ...1490.00000000000002     72.8     31     46
GO:0004842; F:ubiquitin-protein ligase activity; ISS:dictyBase.
GO:0009653; P:anatomical structure morphogenesis; IMP:dictyBase.
164P52482    193   UB2E1_MOUSE Ubiquitin-conjugating enzyme E2 E...1290.00000000000005     72.4     31     46GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
165P51965    193   UB2E1_HUMAN Ubiquitin-conjugating enzyme E2 E...1290.00000000000005     72.4     31     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042296; F:ISG15 ligase activity; IDA:HGNC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.::GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0032020; P:ISG15-protein conjugation; IDA:HGNC.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
166Q941B6    409   UBC37_ARATH Probable ubiquitin-conjugating en...1160.00000000000006     75.1     30     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
167Q16763    222   UBE2S_HUMAN Ubiquitin-conjugating enzyme E2 S...1150.00000000000007     72.4     31     50GO:0005680; C:anaphase-promoting complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0051488; P:activation of anaphase-promoting complex activity; IDA:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; IDA:UniProtKB.::GO:0010994; P:free ubiquitin chain polymerization; IDA:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0044314; P:protein K27-linked ubiquitination; IDA:UniProtKB.::GO:0035519; P:protein K29-linked ubiquitination; IDA:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
168Q86IZ3    149   UBCX_DICDI Ubiquitin-conjugating enzyme E2 pe...1140.0000000000001     70.5     31     54GO:0005777; C:peroxisome; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0016558; P:protein import into peroxisome matrix; ISS:dictyBase.
169Q6P8D9    183   UBC12_XENTR NEDD8-conjugating enzyme Ubc12 OS...1610.0000000000001     71.2     27     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019788; F:NEDD8 ligase activity; ISS:UniProtKB.::GO:0018169; F:ribosomal S6-glutamic acid ligase activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0045116; P:protein neddylation; ISS:UniProtKB.
170P52487    153   UBC84_DROME Ubiquitin-conjugating enzyme E2-1...1580.0000000000001     70.5     29     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
171Q6DCZ9    183   UBC12_XENLA NEDD8-conjugating enzyme Ubc12 OS...1610.0000000000001     70.9     27     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019788; F:NEDD8 ligase activity; ISS:UniProtKB.::GO:0018169; F:ribosomal S6-glutamic acid ligase activity; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0045116; P:protein neddylation; ISS:UniProtKB.
172Q6C9W0    179   UBC12_YARLI NEDD8-conjugating enzyme UBC12 OS...1190.0000000000002     70.5     31     50
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
173Q1RML1    223   UBE2S_BOVIN Ubiquitin-conjugating enzyme E2 S...1150.0000000000002     71.2     31     50GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.::GO:0010994; P:free ubiquitin chain polymerization; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0044314; P:protein K27-linked ubiquitination; ISS:UniProtKB.::GO:0035519; P:protein K29-linked ubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
174Q9XVK5    180   UBC12_CAEEL NEDD8-conjugating enzyme ubc-12 O...1710.0000000000002     70.5     26     50
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019788; F:NEDD8 ligase activity; IDA:UniProtKB.
GO:0000910; P:cytokinesis; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0035046; P:pronuclear migration; IMP:WormBase.::GO:0045116; P:protein neddylation; IDA:UniProtKB.::GO:0016246; P:RNA interference; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
175B5DFI8    223   UBE2S_RAT Ubiquitin-conjugating enzyme E2 S O...1150.0000000000003     70.9     31     50GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.::GO:0010994; P:free ubiquitin chain polymerization; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0044314; P:protein K27-linked ubiquitination; ISS:UniProtKB.::GO:0035519; P:protein K29-linked ubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
176Q921J4    223   UBE2S_MOUSE Ubiquitin-conjugating enzyme E2 S...1150.0000000000003     70.5     31     50GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.::GO:0010994; P:free ubiquitin chain polymerization; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.::GO:0044314; P:protein K27-linked ubiquitination; ISS:UniProtKB.::GO:0035519; P:protein K29-linked ubiquitination; ISS:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
177A1L3K1    223   UB2SA_XENLA Ubiquitin-conjugating enzyme E2 S...1150.0000000000003     70.5     31     50GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.::GO:0010994; P:free ubiquitin chain polymerization; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.
178Q28F89    211   UBE2S_XENTR Ubiquitin-conjugating enzyme E2 S...1200.0000000000003     70.5     30     48GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.::GO:0010994; P:free ubiquitin chain polymerization; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.
179Q5JXB2    153   UE2NL_HUMAN Putative ubiquitin-conjugating en...1390.0000000000004     69.3     31     50
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
180Q6FVQ8    187   UBC12_CANGA NEDD8-conjugating enzyme UBC12 OS...1240.0000000000006     69.3     26     52
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
181C1C3R6    211   UBE2S_LITCT Ubiquitin-conjugating enzyme E2 S...1150.0000000000007     69.3     30     50GO:0005680; C:anaphase-promoting complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0051488; P:activation of anaphase-promoting complex activity; ISS:UniProtKB.::GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0010458; P:exit from mitosis; ISS:UniProtKB.::GO:0010994; P:free ubiquitin chain polymerization; ISS:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; ISS:UniProtKB.
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