Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR047W
Length:
362
Number of sequences:
5887
Description:
YDR047W HEM12 SGDID:S000002454, Chr IV from 551860-552948, Genome Release 64-1-1, Verified ORF, "Uroporphyrinogen decarboxylase, catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; a hem12 mutant has phenotypes similar to patients with porphyria cutanea tarda"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32347    362   DCUP_YEAST Uroporphyrinogen decarboxylase OS=...3620     750     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004853; F:uroporphyrinogen decarboxylase activity; IDA:SGD.
GO:0006783; P:heme biosynthetic process; IMP:SGD.
2Q9USJ5    355   DCUP_SCHPO Uroporphyrinogen decarboxylase OS=...3552e-156     451     59     78GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004853; F:uroporphyrinogen decarboxylase activity; ISS:PomBase.
GO:0006783; P:heme biosynthetic process; ISS:PomBase.
3Q9PTS2    369   DCUP_DANRE Uroporphyrinogen decarboxylase OS=...3551e-137     403     57     71GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
4P06132    367   DCUP_HUMAN Uroporphyrinogen decarboxylase OS=...3562e-124     370     52     69GO:0005829; C:cytosol; TAS:Reactome.::GO:0015630; C:microtubule cytoskeleton; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IDA:UniProtKB.
GO:0006783; P:heme biosynthetic process; IC:UniProtKB.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
5Q5RDK5    367   DCUP_PONAB Uroporphyrinogen decarboxylase OS=...3564e-124     369     52     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
6P70697    367   DCUP_MOUSE Uroporphyrinogen decarboxylase OS=...3562e-122     364     51     67GO:0005829; C:cytosol; IDA:MGI.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IDA:MGI.
GO:0006783; P:heme biosynthetic process; IMP:MGI.
7Q8HY31    367   DCUP_SHEEP Uroporphyrinogen decarboxylase OS=...3563e-122     364     51     67GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
8P32362    364   DCUP_RAT Uroporphyrinogen decarboxylase OS=Ra...3589e-119     355     51     66GO:0005829; C:cytosol; IDA:RGD.
GO:0008198; F:ferrous iron binding; IDA:RGD.::GO:0004853; F:uroporphyrinogen decarboxylase activity; IDA:RGD.
GO:0071243; P:cellular response to arsenic-containing substance; IEP:RGD.::GO:0006783; P:heme biosynthetic process; NAS:RGD.::GO:0001889; P:liver development; IEP:RGD.::GO:0014075; P:response to amine stimulus; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0060992; P:response to fungicide; IEP:RGD.::GO:0010039; P:response to iron ion; IEP:RGD.::GO:0046689; P:response to mercury ion; IEP:RGD.::GO:0051597; P:response to methylmercury; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0046502; P:uroporphyrinogen III metabolic process; IDA:RGD.
9Q2S1W0    354   DCUP_SALRD Uroporphyrinogen decarboxylase OS=...3574e-112     338     46     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
10Q54DF9    364   DCUP_DICDI Uroporphyrinogen decarboxylase OS=...3408e-112     337     50     67GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0004853; F:uroporphyrinogen decarboxylase activity; ISS:dictyBase.
GO:0006783; P:heme biosynthetic process; ISS:dictyBase.
11Q9V595    356   DCUP_DROME Uroporphyrinogen decarboxylase OS=...3555e-108     327     48     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
12A6GVN8    341   DCUP_FLAPJ Uroporphyrinogen decarboxylase OS=...3471e-103     315     47     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
13O18601    386   DCUP_DROVI Uroporphyrinogen decarboxylase OS=...3732e-103     317     46     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006783; P:heme biosynthetic process; IEA:UniProtKB-KW.
14A0M6C4    341   DCUP_GRAFK Uroporphyrinogen decarboxylase OS=...3479e-103     313     46     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
15A5FLE7    341   DCUP_FLAJ1 Uroporphyrinogen decarboxylase OS=...3534e-100     306     45     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
16B2HVF8    357   DCUP_ACIBC Uroporphyrinogen decarboxylase OS=...3585e-97     299     43     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
17A3M795    357   DCUP_ACIBT Uroporphyrinogen decarboxylase OS=...3589e-97     298     43     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
18B0VUQ9    357   DCUP_ACIBS Uroporphyrinogen decarboxylase OS=...3582e-96     298     43     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
19B0VBT2    357   DCUP_ACIBY Uroporphyrinogen decarboxylase OS=...3583e-96     297     43     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
20B7I451    357   DCUP_ACIB5 Uroporphyrinogen decarboxylase OS=...3583e-96     297     43     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
21B7GZK6    357   DCUP_ACIB3 Uroporphyrinogen decarboxylase OS=...3583e-96     297     43     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
22B3QXB5    353   DCUP_CHLT3 Uroporphyrinogen decarboxylase OS=...3497e-96     296     45     63GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
23Q6F9M1    358   DCUP_ACIAD Uroporphyrinogen decarboxylase OS=...3605e-95     294     42     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
24Q11X05    344   DCUP_CYTH3 Uroporphyrinogen decarboxylase OS=...3561e-93     290     44     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
25Q8P6X1    354   DCUP_XANCP Uroporphyrinogen decarboxylase OS=...3603e-93     289     41     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
26B0RQC7    354   DCUP_XANCB Uroporphyrinogen decarboxylase OS=...3603e-93     289     41     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
27Q4UX89    354   DCUP_XANC8 Uroporphyrinogen decarboxylase OS=...3603e-93     289     41     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
28Q489Q8    355   DCUP_COLP3 Uroporphyrinogen decarboxylase OS=...3537e-93     288     42     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
29Q4FRK8    378   DCUP_PSYA2 Uroporphyrinogen decarboxylase OS=...3722e-91     285     41     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
30B3EL29    351   DCUP_CHLPB Uroporphyrinogen decarboxylase OS=...3493e-91     284     42     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
31A5WFU9    368   DCUP_PSYWF Uroporphyrinogen decarboxylase OS=...3611e-90     283     41     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004853; F:uroporphyrinogen decarboxylase activity; IEA:EC.
GO:0006779; P:porphyrin-containing compound biosynthetic process; IEA:UniProtKB-KW.
records
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