Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDR043C
Length:
231
Number of sequences:
5887
Description:
YDR043C NRG1 SGDID:S000002450, Chr IV from 543369-542674, Genome Release 64-1-1, reverse complement, Verified ORF, "Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121P11161    476   EGR2_HUMAN E3 SUMO-protein ligase EGR2 OS=Hom...830.0001     45.8     40     46GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0001102; F:RNA polymerase II activating transcription factor binding; ISS:BHF-UCL.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045444; P:fat cell differentiation; ISS:BHF-UCL.::GO:0006611; P:protein export from nucleus; ISS:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:BHF-UCL.
122Q5RJR4    594   ZN467_RAT Zinc finger protein 467 OS=Rattus n...550.88     34.3     33     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
123Q9JHX2    398   SP5_MOUSE Transcription factor Sp5 OS=Mus mus...660.00004     47.4     30     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060349; P:bone morphogenesis; IGI:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035121; P:tail morphogenesis; IGI:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
124Q6BEB4    398   SP5_HUMAN Transcription factor Sp5 OS=Homo sa...660.00005     47.4     30     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
125Q7TQG0    670   ZBTB5_MOUSE Zinc finger and BTB domain-contai...1200.000001     52.4     33     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
126Q5E9U0    613   SP2_BOVIN Transcription factor Sp2 OS=Bos tau...660.000003     51.2     38     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
127Q9EPU7    560   Z354C_RAT Zinc finger protein 354C OS=Rattus ...514.2     32     35     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.
128Q8N9F8    522   ZN454_HUMAN Zinc finger protein 454 OS=Homo s...572.8     32.7     33     49GO:0005622; C:intracellular; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
129Q02086    613   SP2_HUMAN Transcription factor Sp2 OS=Homo sa...580.000005     50.1     38     59GO:0005634; C:nucleus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006955; P:immune response; TAS:ProtInc.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
130Q569E7    569   ZN697_MOUSE Zinc finger protein 697 OS=Mus mu...430.25     35.8     40     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
131Q05159    412   EGR2B_DANRE Early growth response protein 2b ...830.0001     46.2     40     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
132P0CJ78    1059   ZN865_HUMAN Zinc finger protein 865 OS=Homo s...592.4     33.1     29     46GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
133Q9VDZ3    535   SQZ_DROME Zinc finger protein squeeze OS=Dros...600.0002     45.1     37     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070983; P:dendrite guidance; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0014019; P:neuroblast development; IMP:FlyBase.::GO:0048477; P:oogenesis; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
134Q8TF39    744   ZN483_HUMAN Zinc finger protein 483 OS=Homo s...573.4     32.3     33     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
135Q60636    856   PRDM1_MOUSE PR domain zinc finger protein 1 O...330.09     37.4     45     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0042826; F:histone deacetylase binding; IDA:MGI.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045165; P:cell fate commitment; IMP:MGI.::GO:0001892; P:embryonic placenta development; IMP:MGI.::GO:0007281; P:germ cell development; IGI:MGI.::GO:0001701; P:in utero embryonic development; IMP:MGI.::GO:0001893; P:maternal placenta development; IMP:MGI.::GO:0030889; P:negative regulation of B cell proliferation; IDA:MGI.::GO:0031665; P:negative regulation of lipopolysaccharide-mediated signaling pathway; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0045579; P:positive regulation of B cell differentiation; IDA:MGI.::GO:0010628; P:positive regulation of gene expression; IDA:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
136Q2V3L3    387   Y4634_ARATH Uncharacterized zinc finger prote...450.012     40     38     58GO:0005622; C:intracellular; IEA:InterPro.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
137Q9D2H6    612   SP2_MOUSE Transcription factor Sp2 OS=Mus mus...600.000006     50.1     37     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
138P08047    785   SP1_HUMAN Transcription factor Sp1 OS=Homo sa...620.000006     50.1     37     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:UniProtKB.
GO:0043425; F:bHLH transcription factor binding; ISS:BHF-UCL.::GO:0003690; F:double-stranded DNA binding; IDA:BHF-UCL.::GO:0042826; F:histone deacetylase binding; IPI:BHF-UCL.::GO:0071837; F:HMG box domain binding; IPI:UniProtKB.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:UniProtKB.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; ISS:BHF-UCL.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; ISS:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043923; P:positive regulation by host of viral transcription; IDA:UniProtKB.
139Q9BRH9    671   ZN251_HUMAN Zinc finger protein 251 OS=Homo s...572     33.1     37     49GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
140Q6A085    867   ZN629_MOUSE Zinc finger protein 629 OS=Mus mu...363     32.7     39     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
141P28698    734   MZF1_HUMAN Myeloid zinc finger 1 OS=Homo sapi...550.13     37     33     45GO:0005634; C:nucleus; IDA:HPA.
GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; NAS:ProtInc.::GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0016032; P:viral reproduction; IEA:InterPro.
142Q9EPW2    415   KLF15_MOUSE Krueppel-like factor 15 OS=Mus mu...480.02     39.3     38     58
GO:0003677; F:DNA binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010001; P:glial cell differentiation; IDA:MGI.::GO:0015758; P:glucose transport; IDA:MGI.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
143Q5TEC3    545   ZN697_HUMAN Zinc finger protein 697 OS=Homo s...550.34     35.4     35     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
144Q293Q2    550   SQZ_DROPS Zinc finger protein squeeze OS=Dros...580.0007     43.9     36     60GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
145O89090    784   SP1_MOUSE Transcription factor Sp1 OS=Mus mus...620.000009     49.7     37     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.
GO:0043425; F:bHLH transcription factor binding; IPI:BHF-UCL.::GO:0003690; F:double-stranded DNA binding; IDA:MGI.::GO:0035326; F:enhancer binding; IDA:MGI.::GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IDA:BHF-UCL.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IDA:MGI.::GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:MGI.::GO:0001103; F:RNA polymerase II repressing transcription factor binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0060216; P:definitive hemopoiesis; IGI:MGI.::GO:0048596; P:embryonic camera-type eye morphogenesis; IGI:MGI.::GO:0001892; P:embryonic placenta development; IGI:MGI.::GO:0060136; P:embryonic process involved in female pregnancy; IGI:MGI.::GO:0048706; P:embryonic skeletal system development; IGI:MGI.::GO:0043353; P:enucleate erythrocyte differentiation; IGI:MGI.::GO:0001889; P:liver development; IGI:MGI.::GO:0030324; P:lung development; IGI:MGI.::GO:0030219; P:megakaryocyte differentiation; IGI:MGI.::GO:0001503; P:ossification; IGI:MGI.::GO:0001829; P:trophectodermal cell differentiation; IGI:MGI.
146Q01714    786   SP1_RAT Transcription factor Sp1 OS=Rattus no...620.000009     49.7     37     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:RGD.::GO:0032993; C:protein-DNA complex; IDA:RGD.
GO:0003690; F:double-stranded DNA binding; IDA:RGD.::GO:0035035; F:histone acetyltransferase binding; IPI:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
147Q9UIH9    416   KLF15_HUMAN Krueppel-like factor 15 OS=Homo s...480.018     39.3     38     58GO:0005730; C:nucleolus; IDA:HPA.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0001077; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; IC:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
148P57071    1507   PRD15_HUMAN PR domain zinc finger protein 15 ...540.12     37     41     59GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0003677; F:DNA binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
149Q8BI73    538   ZN775_MOUSE Zinc finger protein 775 OS=Mus mu...586.3     31.6     33     47GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
150Q62445    782   SP4_MOUSE Transcription factor Sp4 OS=Mus mus...590.00005     47.4     36     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008016; P:regulation of heart contraction; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
151Q02446    784   SP4_HUMAN Transcription factor Sp4 OS=Homo sa...590.00003     48.1     37     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003713; F:transcription coactivator activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
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