rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
91 | P11274 | 1271 | BCR_HUMAN Breakpoint cluster region protein O... | 200 | 0.00000002 | 62.4 | 27 | 46 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 92 | Q63358 | 1980 | MYO9B_RAT Unconventional myosin-IXb OS=Rattus... | 169 | 0.00000002 | 62.4 | 27 | 49 | GO:0005884; C:actin filament; IDA:RGD.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:RGD.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0001726; C:ruffle; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:RGD.::GO:0030898; F:actin-dependent ATPase activity; IDA:RGD.::GO:0043531; F:ADP binding; IDA:RGD.::GO:0005524; F:ATP binding; IDA:RGD.::GO:0043008; F:ATP-dependent protein binding; IDA:RGD.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IMP:RGD.::GO:0008270; F:zinc ion binding; IDA:RGD. | | | | | | | | | | GO:0007266; P:Rho protein signal transduction; IDA:RGD. | 93 | Q55GP8 | 684 | GACO_DICDI Rho GTPase-activating protein gacO... | 160 | 0.00000002 | 61.6 | 32 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 94 | P42331 | 645 | RHG25_HUMAN Rho GTPase-activating protein 25 ... | 153 | 0.00000002 | 61.6 | 27 | 54 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 95 | G5E5X0 | 674 | LIMD1_BOVIN LIM domain-containing protein 1 O... | 174 | 0.00000003 | 61.6 | 28 | 44 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0002076; P:osteoblast development; ISS:UniProtKB.::GO:0016310; P:phosphorylation; ISS:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 96 | P85298 | 464 | RHG08_HUMAN Rho GTPase-activating protein 8 O... | 154 | 0.00000003 | 60.8 | 31 | 51 | GO:0005829; C:cytosol; TAS:Reactome. | | | | | | | | | | GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0005100; F:Rho GTPase activator activity; IDA:BHF-UCL. | | | | | | | | | | GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 97 | Q12128 | 409 | BAG7_YEAST Rho-GTPase-activating protein BAG7... | 164 | 0.00000003 | 60.5 | 29 | 54 | GO:0005622; C:intracellular; TAS:SGD. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; IDA:SGD. | | | | | | | | | | GO:0007264; P:small GTPase mediated signal transduction; IPI:SGD. | 98 | Q9R059 | 289 | FHL3_MOUSE Four and a half LIM domains protei... | 74 | 2.8 | 35 | 26 | 41 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 99 | Q9WVM1 | 628 | RGAP1_MOUSE Rac GTPase-activating protein 1 O... | 151 | 0.00000004 | 61.2 | 30 | 50 | GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0097149; C:centralspindlin complex; ISS:UniProtKB.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0051233; C:spindle midzone; ISS:UniProtKB. | | | | | | | | | | GO:0043014; F:alpha-tubulin binding; ISS:UniProtKB.::GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.::GO:0043015; F:gamma-tubulin binding; ISS:UniProtKB.::GO:0005096; F:GTPase activator activity; ISS:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; ISS:UniProtKB. | | | | | | | | | | GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; ISS:UniProtKB.::GO:0007108; P:cytokinesis, initiation of separation; ISS:UniProtKB.::GO:0009790; P:embryo development; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0007405; P:neuroblast proliferation; IEP:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; ISS:UniProtKB.::GO:0007283; P:spermatogenesis; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB. | 100 | P97447 | 280 | FHL1_MOUSE Four and a half LIM domains protei... | 125 | 1.2 | 36.2 | 23 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 101 | Q9WUH4 | 280 | FHL1_RAT Four and a half LIM domains protein ... | 125 | 1.2 | 36.2 | 23 | 39 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. | 102 | Q2M1Z3 | 1444 | RHG31_HUMAN Rho GTPase-activating protein 31 ... | 193 | 0.00000004 | 61.2 | 29 | 49 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 103 | Q86IG9 | 566 | GACH_DICDI Rho GTPase-activating protein gacH... | 152 | 0.00000005 | 60.5 | 28 | 53 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 104 | B5DEH0 | 663 | LIMD1_RAT LIM domain-containing protein 1 OS=... | 174 | 0.00000005 | 60.8 | 28 | 43 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0002076; P:osteoblast development; ISS:UniProtKB.::GO:0016310; P:phosphorylation; ISS:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 105 | Q9V9S7 | 1866 | SYDE_DROME Rho GTPase-activating protein 100F... | 188 | 0.00000005 | 61.2 | 25 | 47 | GO:0005622; C:intracellular; IEA:InterPro.::GO:0048786; C:presynaptic active zone; IDA:FlyBase. | | | | | | | | | | GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB. | | | | | | | | | | GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0048789; P:cytoskeletal matrix organization at active zone; IMP:FlyBase.::GO:0048790; P:maintenance of presynaptic active zone structure; IMP:FlyBase.::GO:0007165; P:signal transduction; IEA:InterPro. | 106 | Q9Z1Z9 | 457 | PDLI7_RAT PDZ and LIM domain protein 7 OS=Rat... | 45 | 0.067 | 40.4 | 38 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0045669; P:positive regulation of osteoblast differentiation; IDA:RGD. | 107 | Q9UGP4 | 676 | LIMD1_HUMAN LIM domain-containing protein 1 O... | 174 | 0.00000007 | 60.5 | 28 | 44 | GO:0000932; C:cytoplasmic mRNA processing body; IDA:MGI.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0016442; C:RNA-induced silencing complex; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc. | | | | | | | | | | GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0033962; P:cytoplasmic mRNA processing body assembly; IMP:MGI.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0035195; P:gene silencing by miRNA; IMP:MGI.::GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0035331; P:negative regulation of hippo signaling cascade; IDA:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; ISS:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0002076; P:osteoblast development; ISS:UniProtKB.::GO:0016310; P:phosphorylation; IDA:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; IMP:UniProtKB.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 108 | Q96HC4 | 596 | PDLI5_HUMAN PDZ and LIM domain protein 5 OS=H... | 34 | 1.3 | 36.6 | 38 | 53 | GO:0015629; C:actin cytoskeleton; IDA:LIFEdb.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003779; F:actin binding; ISS:UniProtKB.::GO:0042805; F:actinin binding; ISS:UniProtKB.::GO:0005080; F:protein kinase C binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0051963; P:regulation of synapse assembly; ISS:UniProtKB. | 109 | Q9H0H5 | 632 | RGAP1_HUMAN Rac GTPase-activating protein 1 O... | 183 | 0.00000007 | 60.1 | 28 | 48 | GO:0001669; C:acrosomal vesicle; IEA:UniProtKB-SubCell.::GO:0097149; C:centralspindlin complex; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0051233; C:spindle midzone; IDA:UniProtKB. | | | | | | | | | | GO:0043014; F:alpha-tubulin binding; IDA:UniProtKB.::GO:0048487; F:beta-tubulin binding; IDA:UniProtKB.::GO:0043015; F:gamma-tubulin binding; IDA:UniProtKB.::GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB. | | | | | | | | | | GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0000915; P:cytokinesis, actomyosin contractile ring assembly; IMP:UniProtKB.::GO:0007108; P:cytokinesis, initiation of separation; IMP:UniProtKB.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0007018; P:microtubule-based movement; TAS:Reactome.::GO:0007405; P:neuroblast proliferation; ISS:UniProtKB.::GO:0071777; P:positive regulation of cell cycle cytokinesis; IDA:UniProtKB.::GO:0051988; P:regulation of attachment of spindle microtubules to kinetochore; IMP:UniProtKB.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007283; P:spermatogenesis; IEP:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; IDA:UniProtKB.::GO:0008272; P:sulfate transport; IDA:UniProtKB. | 110 | Q3TJD7 | 457 | PDLI7_MOUSE PDZ and LIM domain protein 7 OS=M... | 45 | 0.3 | 38.5 | 36 | 51 | GO:0005737; C:cytoplasm; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI.::GO:0001725; C:stress fiber; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0030036; P:actin cytoskeleton organization; IPI:MGI.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW. | 111 | Q9QXD8 | 668 | LIMD1_MOUSE LIM domain-containing protein 1 O... | 174 | 0.00000008 | 60.1 | 28 | 44 | GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016477; P:cell migration; ISS:UniProtKB.::GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0045668; P:negative regulation of osteoblast differentiation; IMP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0002076; P:osteoblast development; IMP:UniProtKB.::GO:0016310; P:phosphorylation; ISS:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0001666; P:response to hypoxia; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 112 | Q92502 | 1023 | STAR8_HUMAN StAR-related lipid transfer prote... | 201 | 0.00000009 | 60.1 | 25 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 113 | Q8WWN8 | 1544 | ARAP3_HUMAN Arf-GAP with Rho-GAP domain, ANK ... | 151 | 0.0000001 | 60.1 | 26 | 48 | GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; ISS:UniProtKB. | | | | | | | | | | GO:0008060; F:ARF GTPase activator activity; ISS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0035024; P:negative regulation of Rho protein signal transduction; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0016192; P:vesicle-mediated transport; TAS:UniProtKB. | 114 | O35115 | 279 | FHL2_RAT Four and a half LIM domains protein ... | 139 | 0.25 | 38.5 | 27 | 41 | GO:0031430; C:M band; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:RGD. | | | | | | | | | | GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 115 | Q811P8 | 2089 | RHG32_MOUSE Rho GTPase-activating protein 32 ... | 146 | 0.0000001 | 60.1 | 34 | 49 | GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005938; C:cell cortex; IDA:MGI.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 116 | O70433 | 279 | FHL2_MOUSE Four and a half LIM domains protei... | 142 | 0.13 | 39.3 | 29 | 41 | GO:0005634; C:nucleus; IDA:BHF-UCL. | | | | | | | | | | GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0055014; P:atrial cardiac muscle cell development; IEP:BHF-UCL.::GO:0060347; P:heart trabecula formation; IEP:BHF-UCL.::GO:0043066; P:negative regulation of apoptotic process; ISS:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0001649; P:osteoblast differentiation; IEP:BHF-UCL.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0055015; P:ventricular cardiac muscle cell development; IEP:BHF-UCL. | 117 | A7KAX9 | 2087 | RHG32_HUMAN Rho GTPase-activating protein 32 ... | 146 | 0.0000001 | 59.7 | 34 | 49 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; IEA:UniProtKB-SubCell.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 118 | Q15311 | 655 | RBP1_HUMAN RalA-binding protein 1 OS=Homo sap... | 181 | 0.0000001 | 59.3 | 27 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IDA:UniProtKB. | | | | | | | | | | GO:0043492; F:ATPase activity, coupled to movement of substances; IDA:UniProtKB.::GO:0030675; F:Rac GTPase activator activity; IDA:UniProtKB.::GO:0048365; F:Rac GTPase binding; IPI:UniProtKB.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB. | | | | | | | | | | GO:0006935; P:chemotaxis; TAS:ProtInc.::GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IPI:UniProtKB.::GO:0006810; P:transport; IDA:UniProtKB. | 119 | Q9VDS5 | 740 | RG92B_DROME Rho GTPase-activating protein 92B... | 151 | 0.0000001 | 59.3 | 29 | 52 | GO:0005737; C:cytoplasm; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 120 | Q86I31 | 885 | GACFF_DICDI Rho GTPase-activating protein gac... | 178 | 0.0000001 | 59.3 | 26 | 47 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 121 | Q8AVG0 | 862 | ABR_XENLA Active breakpoint cluster region-re... | 175 | 0.0000001 | 59.3 | 28 | 47 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro. |