Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL240W
Length:
1017
Number of sequences:
5887
Description:
YDL240W LRG1 SGDID:S000002399, Chr IV from 22823-25876, Genome Release 64-1-1, Verified ORF, "Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity; appears to specifically regulate 1,3-beta-glucan synthesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q6TLK4    869   RHG27_RAT Rho GTPase-activating protein 27 OS...2060.0000000005     67.4     24     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:HGNC.::GO:0017124; F:SH3 domain binding; IDA:HGNC.
GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:HGNC.::GO:0006898; P:receptor-mediated endocytosis; IMP:HGNC.::GO:0007165; P:signal transduction; IEA:InterPro.
62B2RTY4    2548   MYO9A_HUMAN Unconventional myosin-IXa OS=Homo...1500.0000000006     67.8     25     57GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016461; C:unconventional myosin complex; NAS:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007601; P:visual perception; TAS:ProtInc.
63Q9Z1N3    2626   MYO9A_RAT Unconventional myosin-IXa OS=Rattus...1500.0000000006     67.8     25     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
64A2AB59    869   RHG27_MOUSE Rho GTPase-activating protein 27 ...2060.0000000006     67     24     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; ISS:UniProtKB.
GO:0043089; P:positive regulation of Cdc42 GTPase activity; ISS:UniProtKB.::GO:0006898; P:receptor-mediated endocytosis; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
65Q3ZBI6    280   FHL3_BOVIN Four and a half LIM domains protei...651.4     35.8     28     45
GO:0008270; F:zinc ion binding; IEA:InterPro.
66B9VTT2    1091   RHG07_CANFA Rho GTPase-activating protein 7 O...2010.0000000008     67     24     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
67Q9N261    386   LPXN_RABIT Leupaxin OS=Oryctolagus cuniculus ...1561.6     36.2     23     39GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
68Q62172    648   RBP1_MOUSE RalA-binding protein 1 OS=Mus musc...1820.0000000009     66.2     27     49GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; ISS:UniProtKB.
GO:0030675; F:Rac GTPase activator activity; IDA:UniProtKB.::GO:0017160; F:Ral GTPase binding; IPI:UniProtKB.
GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.
69Q9VTU3    476   RG68F_DROME Rho GTPase-activating protein 68F...2130.000000001     65.9     28     44GO:0005622; C:intracellular; IEA:InterPro.
GO:0005100; F:Rho GTPase activator activity; IDA:FlyBase.
GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007370; P:ventral furrow formation; IMP:FlyBase.
70Q9JKS4    723   LDB3_MOUSE LIM domain-binding protein 3 OS=Mu...550.81     37.4     33     51GO:0005856; C:cytoskeleton; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:MGI.
GO:0005080; F:protein kinase C binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
71Q54SL6    531   GACQ_DICDI Rho GTPase-activating protein gacQ...1810.000000001     65.5     29     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
72Q679P3    416   PDLI7_CHICK PDZ and LIM domain protein 7 OS=G...400.18     39.3     40     55GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.
73O60711    386   LPXN_HUMAN Leupaxin OS=Homo sapiens (Human). ...1420.13     39.7     23     39GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0002102; C:podosome; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003712; F:transcription cofactor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; NAS:ProtInc.::GO:0050859; P:negative regulation of B cell receptor signaling pathway; IDA:UniProtKB.::GO:0007162; P:negative regulation of cell adhesion; IDA:UniProtKB.::GO:0006461; P:protein complex assembly; TAS:ProtInc.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
74Q923Q2    1113   STA13_MOUSE StAR-related lipid transfer prote...2880.000000002     65.9     24     45GO:0005811; C:lipid particle; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
75Q13643    280   FHL3_HUMAN Four and a half LIM domains protei...654.3     34.3     28     43
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007517; P:muscle organ development; TAS:ProtInc.
76Q7Z6I6    1101   RHG30_HUMAN Rho GTPase-activating protein 30 ...1920.000000002     65.5     29     48GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
77Q640N3    1101   RHG30_MOUSE Rho GTPase-activating protein 30 ...1920.000000002     65.5     29     47GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
78Q09476    413   PXL1_CAEEL Paxillin homolog 1 OS=Caenorhabdit...591.5     36.2     27     51GO:0005912; C:adherens junction; IDA:WormBase.::GO:0031430; C:M band; IDA:WormBase.::GO:0002102; C:podosome; IDA:WormBase.::GO:0055120; C:striated muscle dense body; IDA:WormBase.
GO:0017166; F:vinculin binding; IPI:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0061061; P:muscle structure development; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0043050; P:pharyngeal pumping; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.
79Q9Y3M8    1113   STA13_HUMAN StAR-related lipid transfer prote...2040.000000004     64.7     25     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005811; C:lipid particle; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
80Q9CXP4    425   RHG08_MOUSE Rho GTPase-activating protein 8 O...1540.000000005     63.2     31     53GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
81Q54VW7    1203   GACGG_DICDI Rho GTPase-activating protein gac...2180.000000005     64.3     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
82A4IF90    471   RHG15_BOVIN Rho GTPase-activating protein 15 ...1980.000000006     63.2     24     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
83Q13459    2157   MYO9B_HUMAN Unconventional myosin-IXb OS=Homo...1220.000000007     63.9     28     55GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0031941; C:filamentous actin; IDA:UniProtKB.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0003779; F:actin binding; IDA:UniProtKB.::GO:0043531; F:ADP binding; IDA:UniProtKB.::GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0016887; F:ATPase activity; IDA:UniProtKB.::GO:0005516; F:calmodulin binding; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0000146; F:microfilament motor activity; IDA:UniProtKB.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.
GO:0030048; P:actin filament-based movement; TAS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; IC:UniProtKB.
84Q8BYW1    648   RHG25_MOUSE Rho GTPase-activating protein 25 ...2260.000000008     63.2     27     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
85Q54NW4    553   LIMB_DICDI LIM domain-containing protein B OS...581.1     37     29     50GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; ISS:dictyBase.
GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.::GO:0007155; P:cell adhesion; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0031154; P:culmination involved in sorocarp development; IMP:dictyBase.
86O94988    1023   FA13A_HUMAN Protein FAM13A OS=Homo sapiens (H...1540.00000001     62.8     28     54GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
87Q8R5G7    1538   ARAP3_MOUSE Arf-GAP with Rho-GAP domain, ANK ...1510.00000002     62.8     27     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030336; P:negative regulation of cell migration; IDA:MGI.::GO:0035021; P:negative regulation of Rac protein signal transduction; IDA:MGI.::GO:0035024; P:negative regulation of Rho protein signal transduction; IDA:MGI.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.
88O74360    933   RGA4_SCHPO Probable Rho-type GTPase-activatin...1560.00000002     62.4     28     54GO:0032153; C:cell division site; IDA:PomBase.::GO:0071944; C:cell periphery; IDA:PomBase.::GO:0005737; C:cytoplasm; IDA:PomBase.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070650; P:actin filament bundle distribution; IMP:PomBase.::GO:0034613; P:cellular protein localization; IGI:PomBase.::GO:0060583; P:regulation of actin cortical patch localization; IMP:PomBase.::GO:0032231; P:regulation of actin filament bundle assembly; IMP:PomBase.::GO:0060305; P:regulation of cell diameter; IMP:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro.
89Q9QY06    2114   MYO9B_MOUSE Unconventional myosin-IXb OS=Mus ...1690.00000002     62.8     27     48GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
90Q6PAJ1    1270   BCR_MOUSE Breakpoint cluster region protein O...2000.00000002     62.4     27     46GO:0005829; C:cytosol; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0030675; F:Rac GTPase activator activity; IGI:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IGI:MGI.::GO:0007420; P:brain development; IGI:MGI.::GO:0042472; P:inner ear morphogenesis; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030336; P:negative regulation of cell migration; IGI:MGI.::GO:0050728; P:negative regulation of inflammatory response; IMP:MGI.::GO:0043314; P:negative regulation of neutrophil degranulation; IGI:MGI.::GO:0050885; P:neuromuscular process controlling balance; IGI:MGI.::GO:0050766; P:positive regulation of phagocytosis; IGI:MGI.::GO:0051726; P:regulation of cell cycle; IDA:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.
91P11274    1271   BCR_HUMAN Breakpoint cluster region protein O...2000.00000002     62.4     27     46GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
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