Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL240W
Length:
1017
Number of sequences:
5887
Description:
YDL240W LRG1 SGDID:S000002399, Chr IV from 22823-25876, Genome Release 64-1-1, Verified ORF, "Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity; appears to specifically regulate 1,3-beta-glucan synthesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
331Q99J31    802   OPHN1_MOUSE Oligophrenin-1 OS=Mus musculus (M...1370.12     40     26     47GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.::GO:0043195; C:terminal button; IDA:MGI.
GO:0003779; F:actin binding; IDA:MGI.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IMP:MGI.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0030100; P:regulation of endocytosis; IMP:MGI.::GO:0051966; P:regulation of synaptic transmission, glutamatergic; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0048488; P:synaptic vesicle endocytosis; IMP:MGI.
332Q1LZ94    158   RBTN2_BOVIN Rhombotin-2 OS=Bos taurus (Bovine...422.1     34.7     36     52
GO:0008270; F:zinc ion binding; IEA:InterPro.
333Q7YQL5    802   OPHN1_PONPY Oligophrenin-1 OS=Pongo pygmaeus ...1370.12     40     26     47GO:0030424; C:axon; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
334Q7YQL6    802   OPHN1_PANTR Oligophrenin-1 OS=Pan troglodytes...1370.12     40     26     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
335Q7Z6B7    1085   SRGP1_HUMAN SLIT-ROBO Rho GTPase-activating p...1550.12     40     27     48GO:0005829; C:cytosol; TAS:Reactome.
GO:0007411; P:axon guidance; TAS:Reactome.
336Q9WTX7    284   FHL5_MOUSE Four and a half LIM domains protei...1601.9     35.4     29     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003713; F:transcription coactivator activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; TAS:MGI.
337O60890    802   OPHN1_HUMAN Oligophrenin-1 OS=Homo sapiens (H...1370.13     40     26     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0007411; P:axon guidance; TAS:ProtInc.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0006930; P:substrate-dependent cell migration, cell extension; TAS:ProtInc.
338O74335    361   RGA5_SCHPO Rho-GTPase-activating protein 5 OS...1540.13     39.3     27     45GO:0051286; C:cell tip; IDA:PomBase.::GO:0031097; C:medial cortex; IDA:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005100; F:Rho GTPase activator activity; IDA:PomBase.
GO:0008360; P:regulation of cell shape; IMP:PomBase.::GO:0090334; P:regulation of cell wall (1->3)-beta-D-glucan biosynthetic process; IMP:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro.
339Q5M8V8    158   RBTN2_XENTR Rhombotin-2 OS=Xenopus tropicalis...422.5     34.3     36     52GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.
340O43900    615   PRIC3_HUMAN Prickle-like protein 3 OS=Homo sa...1400.14     39.7     25     37
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
341Q5PQJ5    1266   RHG29_RAT Rho GTPase-activating protein 29 OS...1770.15     39.7     25     44GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
342Q55DS4    281   LIMG_DICDI LIM domain-containing protein G OS...459.3     33.5     36     51
GO:0008270; F:zinc ion binding; IEA:InterPro.
343P29673    469   APTE_DROME Protein apterous OS=Drosophila mel...1320.43     38.1     27     42GO:0005634; C:nucleus; IDA:FlyBase.
GO:0000977; F:RNA polymerase II regulatory region sequence-specific DNA binding; IDA:FlyBase.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0045165; P:cell fate commitment; NAS:FlyBase.::GO:0007451; P:dorsal/ventral lineage restriction, imaginal disc; TAS:FlyBase.::GO:0007559; P:histolysis; IMP:FlyBase.::GO:0036011; P:imaginal disc-derived leg segmentation; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; TAS:FlyBase.::GO:0007526; P:larval somatic muscle development; IMP:FlyBase.::GO:0007479; P:leg disc proximal/distal pattern formation; IMP:FlyBase.::GO:0007517; P:muscle organ development; IMP:FlyBase.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:FlyBase.::GO:0006351; P:transcription, DNA-dependent; IMP:FlyBase.::GO:0048190; P:wing disc dorsal/ventral pattern formation; IMP:FlyBase.
344Q6DJ06    165   LMO42_XENTR LIM domain transcription factor L...1400.18     37.7     26     40
GO:0003712; F:transcription cofactor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007369; P:gastrulation; IEA:UniProtKB-KW.::GO:0007498; P:mesoderm development; ISS:UniProtKB.::GO:0045665; P:negative regulation of neuron differentiation; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
345Q3B7M5    260   LASP1_BOVIN LIM and SH3 domain protein 1 OS=B...770.19     38.5     31     47GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.
346Q9JKU8    382   LMX1A_MOUSE LIM homeobox transcription factor...1303.4     35     28     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IMP:MGI.::GO:0021953; P:central nervous system neuron differentiation; IMP:MGI.::GO:0021549; P:cerebellum development; IMP:MGI.::GO:0021542; P:dentate gyrus development; IMP:MGI.::GO:0071542; P:dopaminergic neuron differentiation; IMP:MGI.::GO:0030901; P:midbrain development; IMP:MGI.::GO:0045665; P:negative regulation of neuron differentiation; IMP:MGI.::GO:0001558; P:regulation of cell growth; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
347Q04650    382   LMX1A_MESAU LIM homeobox transcription factor...1303.5     35     28     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
348Q8I7C3    657   LASP1_DROME LIM and SH3 domain protein Lasp O...380.24     38.9     45     61GO:0005925; C:focal adhesion; IDA:FlyBase.::GO:0070864; C:sperm individualization complex; IDA:FlyBase.
GO:0003779; F:actin binding; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007279; P:pole cell formation; IMP:FlyBase.::GO:0045856; P:positive regulation of pole plasm oskar mRNA localization; IMP:FlyBase.::GO:0007291; P:sperm individualization; IMP:FlyBase.
349Q7ZXE9    422   TES_XENLA Testin OS=Xenopus laevis (African c...1610.27     38.5     25     38GO:0005938; C:cell cortex; IDA:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0001755; P:neural crest cell migration; IMP:UniProtKB.
350Q14847    261   LASP1_HUMAN LIM and SH3 domain protein 1 OS=H...770.28     38.1     31     48GO:0030864; C:cortical actin cytoskeleton; ISS:UniProtKB.
GO:0015075; F:ion transmembrane transporter activity; ISS:UniProtKB.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
351Q5R5W0    261   LASP1_PONAB LIM and SH3 domain protein 1 OS=P...770.3     38.1     31     48GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006811; P:ion transport; IEA:UniProtKB-KW.
352Q6DIR5    422   TES_XENTR Testin OS=Xenopus tropicalis (Weste...1820.31     38.5     25     38GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; ISS:UniProtKB.
GO:0001755; P:neural crest cell migration; ISS:UniProtKB.
353Q812A2    1099   SRGP3_MOUSE SLIT-ROBO Rho GTPase-activating p...1530.31     38.9     22     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0007165; P:signal transduction; IEA:InterPro.
354Q8CGF1    1266   RHG29_MOUSE Rho GTPase-activating protein 29 ...1770.32     38.9     25     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
355Q9DC07    270   LNEBL_MOUSE LIM zinc-binding domain-containin...400.32     38.1     40     58
GO:0008270; F:zinc ion binding; IEA:InterPro.
356Q10164    1275   RGA2_SCHPO Probable Rho-type GTPase-activatin...1830.33     38.9     24     44GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
357Q2YDK0    284   FHL5_BOVIN Four and a half LIM domains protei...1389.5     33.5     30     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
358P37137    402   LHX5_XENLA LIM/homeobox protein Lhx5 OS=Xenop...1191.6     36.2     25     39GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
359Q9PTJ3    159   RBTN2_DANRE Rhombotin-2 OS=Danio rerio (Zebra...423.3     33.9     36     50GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001568; P:blood vessel development; IMP:ZFIN.::GO:0035162; P:embryonic hemopoiesis; IMP:ZFIN.::GO:0030218; P:erythrocyte differentiation; IGI:ZFIN.
360P61969    165   LMO4_MOUSE LIM domain transcription factor LM...1270.37     37     27     39GO:0005667; C:transcription factor complex; IDA:MGI.
GO:0001158; F:enhancer sequence-specific DNA binding; IDA:MGI.::GO:0008134; F:transcription factor binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031333; P:negative regulation of protein complex assembly; IDA:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IGI:MGI.::GO:0050865; P:regulation of cell activation; IMP:MGI.::GO:0042659; P:regulation of cell fate specification; IMP:MGI.::GO:0021527; P:spinal cord association neuron differentiation; IGI:MGI.::GO:0021522; P:spinal cord motor neuron differentiation; IDA:MGI.::GO:0048538; P:thymus development; IGI:MGI.::GO:0006366; P:transcription from RNA polymerase II promoter; IDA:MGI.::GO:0021514; P:ventral spinal cord interneuron differentiation; IDA:MGI.::GO:0003281; P:ventricular septum development; IMP:MGI.
361P61968    165   LMO4_HUMAN LIM domain transcription factor LM...1270.37     37     27     39GO:0005667; C:transcription factor complex; ISS:UniProtKB.
GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0001843; P:neural tube closure; ISS:UniProtKB.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:UniProtKB.
records
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