Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL240W
Length:
1017
Number of sequences:
5887
Description:
YDL240W LRG1 SGDID:S000002399, Chr IV from 22823-25876, Genome Release 64-1-1, Verified ORF, "Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity; appears to specifically regulate 1,3-beta-glucan synthesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
241Q71M21    1902   RH21B_XENLA Rho GTPase-activating protein 21-...2530.0001     50.4     23     43GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
242O14639    778   ABLM1_HUMAN Actin-binding LIM protein 1 OS=Ho...363.6     35.4     36     61GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0007601; P:visual perception; TAS:ProtInc.
243Q17QN0    334   CHIN_BOVIN N-chimaerin OS=Bos taurus (Bovine)...1520.0001     48.9     25     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.
244Q55DK5    1337   MGP3_DICDI Mental retardation GTPase activati...1600.0001     49.7     28     47GO:0000331; C:contractile vacuole; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
245P53669    647   LIMK1_RAT LIM domain kinase 1 OS=Rattus norve...1220.0002     49.3     28     44GO:0044295; C:axonal growth cone; IDA:RGD.::GO:0005794; C:Golgi apparatus; IDA:RGD.::GO:0005634; C:nucleus; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045773; P:positive regulation of axon extension; ISS:UniProtKB.
246Q96IF1    538   AJUBA_HUMAN LIM domain-containing protein aju...1430.0002     49.3     29     43GO:0005911; C:cell-cell junction; IDA:MGI.::GO:0000932; C:cytoplasmic mRNA processing body; IDA:MGI.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
GO:0045294; F:alpha-catenin binding; IDA:MGI.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0035195; P:gene silencing by miRNA; IMP:MGI.::GO:0035331; P:negative regulation of hippo signaling cascade; IDA:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; IMP:UniProtKB.::GO:0031334; P:positive regulation of protein complex assembly; IDA:MGI.::GO:1900037; P:regulation of cellular response to hypoxia; IDA:UniProtKB.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
247Q9VIS1    1843   CDGAP_DROME GTPase-activating protein CdGAPr ...1410.0002     49.3     30     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0031290; P:retinal ganglion cell axon guidance; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
248P36200    395   LHX3_XENLA LIM/homeobox protein Lhx3 OS=Xenop...292.1     35.8     41     59GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
249Q5U4T3    771   RHG26_XENLA Rho GTPase-activating protein 26 ...1520.0002     48.9     25     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
250Q6PGG2    971   GMIP_MOUSE GEM-interacting protein OS=Mus mus...2180.0002     48.9     23     44GO:0005622; C:intracellular; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
251Q0VA45    674   ZYX_XENTR Zyxin OS=Xenopus tropicalis (Wester...930.076     40.8     26     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0001725; C:stress fiber; ISS:UniProtKB.
GO:0008134; F:transcription factor binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
252Q8K4G5    861   ABLM1_MOUSE Actin-binding LIM protein 1 OS=Mu...943.4     35.4     22     37GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007411; P:axon guidance; IDA:MGI.::GO:0007010; P:cytoskeleton organization; IEA:InterPro.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.
253O42565    615   LIMK1_XENLA LIM domain kinase 1 OS=Xenopus la...930.13     39.7     30     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
254P81128    1513   RHG35_RAT Rho GTPase-activating protein 35 OS...1790.0004     48.1     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
255Q9NRY4    1513   RHG35_HUMAN Rho GTPase-activating protein 35 ...1790.0005     48.1     25     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IC:UniProtKB.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; TAS:Reactome.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; TAS:ProtInc.
256B5DFQ4    759   RHG26_XENTR Rho GTPase-activating protein 26 ...1520.0005     47.8     24     51GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
257Q91Z67    1071   FNBP2_MOUSE SLIT-ROBO Rho GTPase-activating p...1610.0005     47.8     24     47GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
258P83509    1500   RHG35_CANFA Rho GTPase-activating protein 35 ...1790.0006     47.8     24     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042478; P:regulation of eye photoreceptor cell development; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
259Q91V57    459   CHIN_MOUSE N-chimaerin OS=Mus musculus (Mouse...1520.0006     47.4     24     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0048013; P:ephrin receptor signaling pathway; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008045; P:motor axon guidance; IMP:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IDA:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB.
260Q91YM2    1499   RHG35_MOUSE Rho GTPase-activating protein 35 ...1790.0006     47.8     25     41GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; TAS:MGI.
GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0007229; P:integrin-mediated signaling pathway; TAS:MGI.::GO:0043116; P:negative regulation of vascular permeability; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
261B2RWW0    714   TAGAP_MOUSE T-cell activation Rho GTPase-acti...1940.0007     47.4     29     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
262P48059    325   LIMS1_HUMAN LIM and senescent cell antigen-li...813.1     35     27     38GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0007569; P:cell aging; TAS:ProtInc.::GO:0034329; P:cell junction assembly; TAS:Reactome.::GO:0071560; P:cellular response to transforming growth factor beta stimulus; IEP:UniProtKB.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.
263Q99JW4    325   LIMS1_MOUSE LIM and senescent cell antigen-li...813.3     35     27     38GO:0005925; C:focal adhesion; IDA:MGI.
GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016337; P:cell-cell adhesion; IMP:MGI.::GO:0007160; P:cell-matrix adhesion; IMP:MGI.::GO:0043009; P:chordate embryonic development; IMP:MGI.::GO:0007163; P:establishment or maintenance of cell polarity; IMP:MGI.
264Q15654    476   TRIP6_HUMAN Thyroid receptor-interacting prot...1340.019     42.4     25     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005149; F:interleukin-1 receptor binding; IDA:UniProtKB.::GO:0019900; F:kinase binding; IPI:UniProtKB.::GO:0046966; F:thyroid hormone receptor binding; NAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048041; P:focal adhesion assembly; NAS:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0008588; P:release of cytoplasmic sequestered NF-kappaB; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
265Q5VT97    1194   SYDE2_HUMAN Rho GTPase-activating protein SYD...2160.0008     47.4     25     44GO:0005829; C:cytosol; TAS:Reactome.
GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.
GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
266Q6INE5    507   RHG19_XENLA Rho GTPase-activating protein 19 ...2540.0008     47     28     45GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
267Q20498    759   RRC1_CAEEL GTPase-activating protein rrc-1 OS...1580.0009     47     27     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007165; P:signal transduction; IEA:InterPro.
268Q5ZMW5    760   RHG26_CHICK Rho GTPase-activating protein 26 ...1520.001     47     25     49GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
269O75044    1071   FNBP2_HUMAN SLIT-ROBO Rho GTPase-activating p...1610.001     47     23     47GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
270Q54E35    570   GACEE_DICDI Rho GTPase-activating protein gac...1650.001     46.6     26     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
271Q54GD0    920   MGP1_DICDI Mental retardation GTPase activati...1810.001     47     25     49GO:0000331; C:contractile vacuole; IDA:dictyBase.::GO:0005829; C:cytosol; IDA:dictyBase.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0033298; P:contractile vacuole organization; IMP:dictyBase.::GO:0006887; P:exocytosis; IGI:dictyBase.::GO:0051490; P:negative regulation of filopodium assembly; IMP:dictyBase.::GO:0042331; P:phototaxis; IGI:dictyBase.::GO:0051270; P:regulation of cellular component movement; IMP:dictyBase.::GO:0007165; P:signal transduction; IEA:InterPro.
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