| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
211 | Q9HF75 | 2071 | BEM2_ASHGO GTPase-activating protein BEM2 OS=... | 191 | 0.00003 | 52.4 | 24 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. | 212 | P53670 | 638 | LIMK2_RAT LIM domain kinase 2 OS=Rattus norve... | 100 | 0.00003 | 52 | 31 | 43 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007286; P:spermatid development; TAS:RGD. | 213 | Q6DE55 | 1107 | HMHA1_XENLA Minor histocompatibility protein ... | 174 | 0.00003 | 52 | 26 | 46 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 214 | Q503U0 | 145 | LMO3_DANRE LIM domain only protein 3 OS=Danio... | 141 | 0.00003 | 48.9 | 28 | 43 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 215 | Q5T5U3 | 1957 | RHG21_HUMAN Rho GTPase-activating protein 21 ... | 311 | 0.00003 | 52 | 23 | 40 | GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0051683; P:establishment of Golgi localization; IDA:BHF-UCL.::GO:0007030; P:Golgi organization; IMP:BHF-UCL.::GO:0051684; P:maintenance of Golgi location; IMP:BHF-UCL.::GO:0072384; P:organelle transport along microtubule; IMP:BHF-UCL.::GO:0007165; P:signal transduction; IEA:InterPro. | 216 | P53671 | 638 | LIMK2_HUMAN LIM domain kinase 2 OS=Homo sapie... | 100 | 0.00003 | 51.6 | 26 | 43 | GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005634; C:nucleus; TAS:UniProtKB. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0042325; P:regulation of phosphorylation; IEA:InterPro. | 217 | Q9YH16 | 156 | LMO3_XENLA LIM domain only protein 3 OS=Xenop... | 141 | 0.00003 | 48.9 | 28 | 43 | | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | | 218 | Q93052 | 612 | LPP_HUMAN Lipoma-preferred partner OS=Homo sa... | 41 | 5.7 | 34.7 | 32 | 56 | GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 219 | O54785 | 638 | LIMK2_MOUSE LIM domain kinase 2 OS=Mus muscul... | 111 | 0.00003 | 51.6 | 29 | 41 | GO:0005801; C:cis-Golgi network; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007283; P:spermatogenesis; IMP:MGI. | 220 | Q1JQB5 | 378 | FBLI1_BOVIN Filamin-binding LIM protein 1 OS=... | 38 | 1.5 | 36.2 | 29 | 63 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; ISS:UniProtKB. | | | | | | | | | | GO:0031005; F:filamin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0033623; P:regulation of integrin activation; ISS:UniProtKB. | 221 | Q5U2Z2 | 548 | AJUBA_RAT LIM domain-containing protein ajuba... | 143 | 0.00004 | 51.2 | 30 | 43 | GO:0005911; C:cell-cell junction; IDA:MGI.::GO:0000932; C:cytoplasmic mRNA processing body; ISS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 222 | P53776 | 390 | LHX4_MOUSE LIM/homeobox protein Lhx4 OS=Mus m... | 47 | 4.4 | 34.7 | 36 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006916; P:anti-apoptosis; IMP:MGI.::GO:0021526; P:medial motor column neuron differentiation; IGI:MGI.::GO:0008045; P:motor axon guidance; IGI:MGI.::GO:0009887; P:organ morphogenesis; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 223 | Q969G2 | 390 | LHX4_HUMAN LIM/homeobox protein Lhx4 OS=Homo ... | 47 | 4.2 | 34.7 | 36 | 49 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 224 | Q7TQJ8 | 398 | WTIP_MOUSE Wilms tumor protein 1-interacting ... | 139 | 1.2 | 36.6 | 26 | 38 | GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0000932; C:cytoplasmic mRNA processing body; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 225 | Q91XC0 | 547 | AJUBA_MOUSE LIM domain-containing protein aju... | 143 | 0.00005 | 50.8 | 30 | 43 | GO:0000932; C:cytoplasmic mRNA processing body; ISS:UniProtKB.::GO:0005829; C:cytosol; IDA:MGI.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI. | | | | | | | | | | GO:0051015; F:actin filament binding; IDA:MGI.::GO:0045294; F:alpha-catenin binding; IDA:MGI.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0003714; F:transcription corepressor activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016339; P:calcium-dependent cell-cell adhesion; IMP:MGI.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0034613; P:cellular protein localization; IMP:MGI.::GO:0048041; P:focal adhesion assembly; IMP:MGI.::GO:0046474; P:glycerophospholipid biosynthetic process; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IMP:MGI.::GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0033673; P:negative regulation of kinase activity; IDA:MGI.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0031328; P:positive regulation of cellular biosynthetic process; IMP:MGI.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0043406; P:positive regulation of MAP kinase activity; IDA:MGI.::GO:0030334; P:regulation of cell migration; IDA:MGI.::GO:0043087; P:regulation of GTPase activity; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035313; P:wound healing, spreading of epidermal cells; IMP:MGI. | 226 | P53412 | 395 | LHX3_CHICK LIM/homeobox protein Lhx3 OS=Gallu... | 87 | 3.9 | 34.7 | 25 | 43 | | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 227 | Q71FD7 | 375 | FBLI1_MOUSE Filamin-binding LIM protein 1 OS=... | 37 | 2.1 | 35.8 | 30 | 62 | GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; ISS:UniProtKB. | | | | | | | | | | GO:0031005; F:filamin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0033623; P:regulation of integrin activation; ISS:UniProtKB. | 228 | P50481 | 400 | LHX3_MOUSE LIM/homeobox protein Lhx3 OS=Mus m... | 41 | 2.9 | 35.4 | 34 | 54 | GO:0005667; C:transcription factor complex; IDA:MGI. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0000988; F:protein binding transcription factor activity; IPI:MGI.::GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0021526; P:medial motor column neuron differentiation; IGI:MGI.::GO:0008045; P:motor axon guidance; IGI:MGI.::GO:0043066; P:negative regulation of apoptotic process; IMP:MGI.::GO:0021983; P:pituitary gland development; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0021527; P:spinal cord association neuron differentiation; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0021521; P:ventral spinal cord interneuron specification; IDA:MGI. | 229 | Q9C0H5 | 1083 | RHG39_HUMAN Rho GTPase-activating protein 39 ... | 134 | 0.00006 | 50.8 | 31 | 49 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007411; P:axon guidance; TAS:Reactome.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 230 | P15882 | 459 | CHIN_HUMAN N-chimaerin OS=Homo sapiens (Human... | 152 | 0.00006 | 50.4 | 25 | 48 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc. | | | | | | | | | | GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 231 | P53668 | 647 | LIMK1_MOUSE LIM domain kinase 1 OS=Mus muscul... | 122 | 0.00007 | 50.4 | 29 | 44 | GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005925; C:focal adhesion; IDA:MGI.::GO:0043005; C:neuron projection; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:MGI. | | | | | | | | | | GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0045773; P:positive regulation of axon extension; IGI:MGI. | 232 | Q14CB8 | 494 | RHG19_HUMAN Rho GTPase-activating protein 19 ... | 162 | 0.00007 | 50.4 | 30 | 54 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome. | 233 | Q90421 | 398 | LHX3_DANRE LIM/homeobox protein Lhx3 OS=Danio... | 35 | 4.5 | 34.7 | 37 | 54 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 234 | A5H447 | 663 | ZYX_XENLA Zyxin OS=Xenopus laevis (African cl... | 92 | 0.63 | 37.7 | 26 | 46 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; ISS:UniProtKB.::GO:0001725; C:stress fiber; ISS:UniProtKB. | | | | | | | | | | GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 235 | Q3TBD2 | 1116 | HMHA1_MOUSE Minor histocompatibility protein ... | 175 | 0.00008 | 50.4 | 25 | 43 | GO:0005622; C:intracellular; IEA:InterPro. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. | | | | | | | | | | GO:0035556; P:intracellular signal transduction; IEA:InterPro. | 236 | E1BKA3 | 548 | AJUBA_BOVIN LIM domain-containing protein aju... | 143 | 0.00008 | 50.1 | 29 | 43 | GO:0000932; C:cytoplasmic mRNA processing body; ISS:UniProtKB.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035331; P:negative regulation of hippo signaling cascade; ISS:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 237 | Q54F80 | 514 | GACD_DICDI Rho GTPase-activating protein gacD... | 203 | 0.00008 | 50.1 | 28 | 44 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 238 | P59281 | 1107 | RHG39_MOUSE Rho GTPase-activating protein 39 ... | 134 | 0.00009 | 50.4 | 31 | 46 | GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. | 239 | Q8BFW7 | 613 | LPP_MOUSE Lipoma-preferred partner homolog OS... | 41 | 3.4 | 35.4 | 32 | 59 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0007155; P:cell adhesion; IEA:UniProtKB-KW. | 240 | Q9VY77 | 728 | AJUBA_DROME LIM domain-containing protein jub... | 140 | 0.0001 | 50.1 | 27 | 42 | GO:0005912; C:adherens junction; IDA:FlyBase. | | | | | | | | | | GO:0003779; F:actin binding; ISS:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro. | | | | | | | | | | GO:0035329; P:hippo signaling cascade; IMP:FlyBase.::GO:0045572; P:positive regulation of imaginal disc growth; IMP:FlyBase. | 241 | Q71M21 | 1902 | RH21B_XENLA Rho GTPase-activating protein 21-... | 253 | 0.0001 | 50.4 | 23 | 43 | GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro. | | | | | | | | | | GO:0007165; P:signal transduction; IEA:InterPro. |
