Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL240W
Length:
1017
Number of sequences:
5887
Description:
YDL240W LRG1 SGDID:S000002399, Chr IV from 22823-25876, Genome Release 64-1-1, Verified ORF, "Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity; appears to specifically regulate 1,3-beta-glucan synthesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181P34288    1605   PAC1_CAEEL GTPase-activating protein pac-1 OS...1690.000006     54.3     24     47GO:0030054; C:cell junction; IDA:WormBase.::GO:0005737; C:cytoplasm; NAS:UniProtKB.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.
GO:0008105; P:asymmetric protein localization; IMP:WormBase.::GO:0010470; P:regulation of gastrulation; IMP:WormBase.::GO:0007266; P:Rho protein signal transduction; IDA:UniProtKB.
182Q6P7E4    419   PDLI7_DANRE PDZ and LIM domain protein 7 OS=D...606.5     34.3     35     43GO:0031941; C:filamentous actin; IDA:ZFIN.::GO:0048471; C:perinuclear region of cytoplasm; IDA:ZFIN.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0003294; P:atrial ventricular junction remodeling; IMP:ZFIN.::GO:0003190; P:atrioventricular valve formation; IMP:ZFIN.::GO:0001947; P:heart looping; IMP:ZFIN.::GO:0001756; P:somitogenesis; IMP:ZFIN.
183Q92619    1136   HMHA1_HUMAN Minor histocompatibility protein ...1800.000007     53.9     27     43GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
184Q0P5B3    156   RBTN1_BOVIN Rhombotin-1 OS=Bos taurus (Bovine...1410.000007     50.8     28     44GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
185P20154    405   LIN11_CAEEL Protein lin-11 OS=Caenorhabditis ...650.15     39.3     29     45GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007413; P:axonal fasciculation; IMP:WormBase.::GO:0001708; P:cell fate specification; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040026; P:positive regulation of vulval development; IMP:WormBase.::GO:0045595; P:regulation of cell differentiation; IMP:WormBase.::GO:0030334; P:regulation of cell migration; IMP:WormBase.
186Q4LDD4    1452   ARAP1_MOUSE Arf-GAP with Rho-GAP domain, ANK ...1720.000009     53.5     27     49GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0070412; F:R-SMAD binding; ISS:BHF-UCL.::GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007184; P:SMAD protein import into nucleus; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
187Q86NH1    987   SYD1_CAEEL Rho GTPase-activating protein syd-...1560.000009     53.5     26     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0042734; C:presynaptic membrane; IDA:WormBase.
GO:0005100; F:Rho GTPase activator activity; IMP:UniProtKB.
GO:0032862; P:activation of Rho GTPase activity; IMP:UniProtKB.::GO:0008088; P:axon cargo transport; IGI:WormBase.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; IMP:UniProtKB.::GO:0034613; P:cellular protein localization; IGI:WormBase.::GO:0040011; P:locomotion; IGI:WormBase.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
188B1AUC7    590   RHG36_MOUSE Rho GTPase-activating protein 36 ...1340.00001     53.1     31     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
189Q9NYF5    915   FA13B_HUMAN Protein FAM13B OS=Homo sapiens (H...1860.00001     53.5     26     48GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
190Q8K2H3    851   FA13B_MOUSE Protein FAM13B OS=Mus musculus (M...1860.00001     53.1     26     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
191Q9P227    1491   RHG23_HUMAN Rho GTPase-activating protein 23 ...1670.00001     53.5     25     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
192Q6PCS4    1337   RHG29_DANRE Rho GTPase-activating protein 29 ...2250.00001     53.5     25     43GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
193Q5RB40    1163   HMHA1_PONAB Minor histocompatibility protein ...1800.00001     53.5     26     43GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
194Q80YF9    1305   RHG33_MOUSE Rho GTPase-activating protein 33 ...1870.00001     53.1     30     48GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
195Q55CK2    877   MGP2_DICDI Mental retardation GTPase activati...1730.00001     52.8     28     49GO:0000331; C:contractile vacuole; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0033298; P:contractile vacuole organization; IGI:dictyBase.::GO:0006887; P:exocytosis; IGI:dictyBase.::GO:0051490; P:negative regulation of filopodium assembly; IMP:dictyBase.::GO:0042331; P:phototaxis; IGI:dictyBase.::GO:0051270; P:regulation of cellular component movement; IMP:dictyBase.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0030587; P:sorocarp development; IMP:dictyBase.
196Q32L23    638   LIMK2_BOVIN LIM domain kinase 2 OS=Bos taurus...1110.00001     52.8     27     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
197P53666    642   LIMK2_CHICK LIM domain kinase 2 OS=Gallus gal...1000.00002     52.8     31     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
198Q69ZH9    1483   RHG23_MOUSE Rho GTPase-activating protein 23 ...1670.00002     52.8     25     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
199Q9UBR4    397   LHX3_HUMAN LIM/homeobox protein Lhx3 OS=Homo ...411.5     36.2     34     54GO:0005634; C:nucleus; TAS:ProtInc.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0048839; P:inner ear development; IEP:UniProtKB.::GO:0009887; P:organ morphogenesis; TAS:ProtInc.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
200O14559    1287   RHG33_HUMAN Rho GTPase-activating protein 33 ...1850.00002     52.8     30     49
GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
201Q6DFV3    1944   RHG21_MOUSE Rho GTPase-activating protein 21 ...3040.00002     52.8     24     40GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
202Q54XE8    576   GACP_DICDI Rho GTPase-activating protein gacP...2060.00002     52     30     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
203Q54QF4    909   MGP4_DICDI Mental retardation GTPase activati...1580.00002     52.4     26     50GO:0000331; C:contractile vacuole; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
204Q5RBW7    145   LMO3_PONAB LIM domain only protein 3 OS=Pongo...1410.00002     49.3     28     43
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
205Q8BZL8    145   LMO3_MOUSE LIM domain only protein 3 OS=Mus m...1410.00002     49.3     28     43
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
206Q8TAP4    145   LMO3_HUMAN LIM domain only protein 3 OS=Homo ...1410.00002     49.3     28     43
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
207Q2KIA3    145   LMO3_BOVIN LIM domain only protein 3 OS=Bos t...1410.00002     49.3     28     43
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
208O97581    383   LHX3_PIG LIM/homeobox protein Lhx3 OS=Sus scr...411.8     35.8     34     54GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; NAS:UniProtKB.
GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
209Q5XI07    632   LPP_RAT Lipoma-preferred partner homolog OS=R...412.4     35.8     32     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
210A6NIX2    430   WTIP_HUMAN Wilms tumor protein 1-interacting ...1440.00003     51.6     31     44GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0000932; C:cytoplasmic mRNA processing body; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0035195; P:gene silencing by miRNA; IMP:MGI.::GO:0035331; P:negative regulation of hippo signaling cascade; IDA:UniProtKB.::GO:2000637; P:positive regulation of gene silencing by miRNA; IMP:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0001666; P:response to hypoxia; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
211Q9HF75    2071   BEM2_ASHGO GTPase-activating protein BEM2 OS=...1910.00003     52.4     24     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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