Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL240W
Length:
1017
Number of sequences:
5887
Description:
YDL240W LRG1 SGDID:S000002399, Chr IV from 22823-25876, Genome Release 64-1-1, Verified ORF, "Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity; appears to specifically regulate 1,3-beta-glucan synthesis"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q8AVG0    862   ABR_XENLA Active breakpoint cluster region-re...1750.0000001     59.3     28     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
122Q03070    295   CHIO_RAT Beta-chimaerin OS=Rattus norvegicus ...1560.0000001     57.8     26     46GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0001565; F:phorbol ester receptor activity; TAS:RGD.::GO:0030675; F:Rac GTPase activator activity; IDA:RGD.
GO:0001675; P:acrosome assembly; IEP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
123A6X8Z5    1425   RHG31_MOUSE Rho GTPase-activating protein 31 ...1930.0000002     59.3     29     51GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0030027; C:lamellipodium; IDA:MGI.
GO:0005096; F:GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IDA:MGI.
GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.
124Q8IR79    1257   LIMK1_DROME LIM domain kinase 1 OS=Drosophila...1270.0000002     59.3     28     44GO:0005826; C:actomyosin contractile ring; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IDA:UniProtKB.::GO:0048749; P:compound eye development; IGI:FlyBase.::GO:0001737; P:establishment of imaginal disc-derived wing hair orientation; IMP:FlyBase.::GO:0050770; P:regulation of axonogenesis; IMP:FlyBase.::GO:0051124; P:synaptic growth at neuromuscular junction; IMP:FlyBase.
125Q61CA4    962   SYD1_CAEBR Rho GTPase-activating protein syd-...1290.0000002     58.9     27     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0045202; C:synapse; ISS:UniProtKB.
GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.
GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030030; P:cell projection organization; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
126Q80XD1    332   CHIO_MOUSE Beta-chimaerin OS=Mus musculus (Mo...1560.0000002     57.8     26     46GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
127Q8WZ64    1704   ARAP2_HUMAN Arf-GAP with Rho-GAP domain, ANK ...2710.0000002     58.9     25     48GO:0005829; C:cytosol; TAS:Reactome.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
128Q559A0    1164   GACU_DICDI Rho GTPase-activating protein gacU...1890.0000003     58.5     29     49GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
129A9LS46    690   WTIP_XENLA Wilms tumor protein 1-interacting ...951.1     37     29     46GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0014032; P:neural crest cell development; IMP:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
130Q3SX40    424   PDLI7_BOVIN PDZ and LIM domain protein 7 OS=B...450.087     40     38     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.
131Q14192    279   FHL2_HUMAN Four and a half LIM domains protei...841.1     36.2     29     49GO:0015629; C:actin cytoskeleton; IDA:HPA.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0050681; F:androgen receptor binding; NAS:UniProtKB.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0003713; F:transcription coactivator activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030521; P:androgen receptor signaling pathway; NAS:UniProtKB.::GO:0044255; P:cellular lipid metabolic process; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0009725; P:response to hormone stimulus; IMP:BHF-UCL.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
132Q5ZMM3    475   RHG15_CHICK Rho GTPase-activating protein 15 ...2170.0000003     57.8     23     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
133Q53QZ3    475   RHG15_HUMAN Rho GTPase-activating protein 15 ...1980.0000004     57.4     23     45GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI.
GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
134E9Q6X9    672   RHG40_MOUSE Rho GTPase-activating protein 40 ...1850.0000004     57.8     32     53GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
135A8DZE6    648   WTIP_DANRE Wilms tumor protein 1-interacting ...1740.0000004     57.8     28     42GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0014032; P:neural crest cell development; ISS:UniProtKB.::GO:0022604; P:regulation of cell morphogenesis; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
136Q8K031    1019   STAR8_MOUSE StAR-related lipid transfer prote...1850.0000004     57.8     26     48GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
137A4II46    862   ABR_XENTR Active breakpoint cluster region-re...1790.0000005     57.8     25     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
138Q06BR1    612   LIMD1_XENLA LIM domain-containing protein 1 O...1710.0000005     57.4     27     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0014032; P:neural crest cell development; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
139P52757    468   CHIO_HUMAN Beta-chimaerin OS=Homo sapiens (Hu...1560.0000005     57     25     46GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
140Q8CI51    591   PDLI5_MOUSE PDZ and LIM domain protein 5 OS=M...341.7     36.2     38     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0045211; C:postsynaptic membrane; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:MGI.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0061001; P:regulation of dendritic spine morphogenesis; ISS:UniProtKB.::GO:0051963; P:regulation of synapse assembly; ISS:UniProtKB.
141Q9NR12    457   PDLI7_HUMAN PDZ and LIM domain protein 7 OS=H...450.13     39.7     38     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0006898; P:receptor-mediated endocytosis; TAS:ProtInc.
142Q811M1    481   RHG15_MOUSE Rho GTPase-activating protein 15 ...1980.0000007     56.6     23     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
143B7ZUL2    593   LIMD1_XENTR LIM domain-containing protein 1 O...1430.0000008     56.6     27     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003714; F:transcription corepressor activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0014032; P:neural crest cell development; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
144Q6GPD0    1940   RHG32_XENLA Rho GTPase-activating protein 32 ...1430.0000008     57     31     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
145Q5F3G0    495   RHG19_CHICK Rho GTPase-activating protein 19 ...2530.0000008     56.6     27     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
146Q5REN1    375   FBLI1_PONAB Filamin-binding LIM protein 1 OS=...654     34.7     31     52GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0001725; C:stress fiber; ISS:UniProtKB.
GO:0031005; F:filamin binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016337; P:cell-cell adhesion; ISS:UniProtKB.::GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.::GO:0033623; P:regulation of integrin activation; ISS:UniProtKB.
147Q8BZ05    1703   ARAP2_MOUSE Arf-GAP with Rho-GAP domain, ANK ...2680.0000009     57     24     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
148Q86L99    1523   GACHH_DICDI Rho GTPase-activating protein gac...1500.0000009     57     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
149A7MB27    530   RHG36_BOVIN Rho GTPase-activating protein 36 ...1700.000001     56.2     27     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
150Q62523    564   ZYX_MOUSE Zyxin OS=Mus musculus (Mouse). GN=Z...410.33     38.5     39     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
151Q5SSL4    859   ABR_MOUSE Active breakpoint cluster region-re...1790.000001     56.2     25     47GO:0005829; C:cytosol; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0030675; F:Rac GTPase activator activity; IDA:MGI.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IGI:MGI.::GO:0007420; P:brain development; IGI:MGI.::GO:0042472; P:inner ear morphogenesis; IGI:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0030336; P:negative regulation of cell migration; IGI:MGI.::GO:0050728; P:negative regulation of inflammatory response; IMP:MGI.::GO:0043314; P:negative regulation of neutrophil degranulation; IGI:MGI.::GO:0050885; P:neuromuscular process controlling balance; IGI:MGI.::GO:0050766; P:positive regulation of phagocytosis; IGI:MGI.::GO:0032496; P:response to lipopolysaccharide; IMP:MGI.
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