Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YDL230W
Length:
335
Number of sequences:
5887
Description:
YDL230W PTP1 SGDID:S000002389, Chr IV from 42700-43707, Genome Release 64-1-1, Verified ORF, "Phosphotyrosine-specific protein phosphatase that dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria; proposed to be a negative regulator of filamentation"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91P54637    990   PTP3_DICDI Tyrosine-protein phosphatase 3 OS=...2842e-23     105     30     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0007243; P:intracellular protein kinase cascade; IMP:dictyBase.::GO:0034504; P:protein localization to nucleus; IMP:dictyBase.::GO:0006970; P:response to osmotic stress; IMP:dictyBase.::GO:0042501; P:serine phosphorylation of STAT protein; IMP:dictyBase.
92O02695    1013   PTPR2_MACNE Receptor-type tyrosine-protein ph...2942e-23     105     30     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
93Q92932    1015   PTPR2_HUMAN Receptor-type tyrosine-protein ph...2943e-23     105     30     47GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
94Q641Z2    593   PTN9_RAT Tyrosine-protein phosphatase non-rec...3003e-23     103     29     44
GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
95Q16849    979   PTPRN_HUMAN Receptor-type tyrosine-protein ph...2914e-23     104     30     46GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0000302; P:response to reactive oxygen species; IDA:UniProtKB.
96O35239    593   PTN9_MOUSE Tyrosine-protein phosphatase non-r...3005e-23     103     28     41
GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
97Q63259    983   PTPRN_RAT Receptor-type tyrosine-protein phos...2915e-23     104     30     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:RGD.
GO:0051020; F:GTPase binding; IPI:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0019221; P:cytokine-mediated signaling pathway; IDA:RGD.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0043627; P:response to estrogen stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0019932; P:second-messenger-mediated signaling; TAS:RGD.
98P56722    979   PTPRN_BOVIN Receptor-type tyrosine-protein ph...2916e-23     103     30     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.
99P34138    377   PTP2_DICDI Tyrosine-protein phosphatase 2 OS=...2487e-23     100     29     50
GO:0004725; F:protein tyrosine phosphatase activity; IDA:dictyBase.
GO:0031152; P:aggregation involved in sorocarp development; IMP:dictyBase.
100Q60673    979   PTPRN_MOUSE Receptor-type tyrosine-protein ph...2918e-23     103     30     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; TAS:MGI.::GO:0005886; C:plasma membrane; TAS:MGI.
GO:0004725; F:protein tyrosine phosphatase activity; TAS:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:MGI.
101P54829    565   PTN5_HUMAN Tyrosine-protein phosphatase non-r...2829e-23     102     29     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:UniProtKB.
GO:0001784; F:phosphotyrosine binding; IDA:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:UniProtKB.
102Q90687    593   PTN11_CHICK Tyrosine-protein phosphatase non-...2911e-22     102     30     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
103Q9W0G1    548   PTP61_DROME Tyrosine-protein phosphatase non-...2811e-22     102     27     45GO:0012505; C:endomembrane system; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.::GO:0005740; C:mitochondrial envelope; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0048471; C:perinuclear region of cytoplasm; IDA:FlyBase.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:FlyBase.
GO:0007411; P:axon guidance; IPI:FlyBase.::GO:0071456; P:cellular response to hypoxia; IMP:FlyBase.::GO:0007377; P:germ-band extension; IDA:UniProtKB.::GO:0000278; P:mitotic cell cycle; IMP:FlyBase.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:FlyBase.::GO:0032880; P:regulation of protein localization; IDA:FlyBase.::GO:0031647; P:regulation of protein stability; IMP:FlyBase.
104P70289    1705   PTPRV_MOUSE Receptor-type tyrosine-protein ph...2801e-22     103     30     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
105P41499    597   PTN11_RAT Tyrosine-protein phosphatase non-re...2952e-22     101     30     45GO:0005829; C:cytosol; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0043560; F:insulin receptor substrate binding; IPI:RGD.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0043274; F:phospholipase binding; IDA:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD.
GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.
106Q63475    1004   PTPR2_RAT Receptor-type tyrosine-protein phos...2883e-22     102     30     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD.::GO:0043195; C:terminal button; IDA:RGD.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0034260; P:negative regulation of GTPase activity; IDA:RGD.
107Q06124    597   PTN11_HUMAN Tyrosine-protein phosphatase non-...3003e-22     101     31     46GO:0005829; C:cytosol; TAS:Reactome.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IMP:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0048013; P:ephrin receptor signaling pathway; IDA:UniProtKB.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0033628; P:regulation of cell adhesion mediated by integrin; IMP:UniProtKB.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.
108P35235    597   PTN11_MOUSE Tyrosine-protein phosphatase non-...2944e-22     100     30     47GO:0005829; C:cytosol; TAS:Reactome.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0051428; F:peptide hormone receptor binding; IPI:MGI.::GO:0030971; F:receptor tyrosine kinase binding; IPI:UniProtKB.
GO:0000187; P:activation of MAPK activity; IMP:MGI.::GO:0007409; P:axonogenesis; IMP:MGI.::GO:0000077; P:DNA damage checkpoint; IMP:MGI.::GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0042593; P:glucose homeostasis; IMP:MGI.::GO:0042445; P:hormone metabolic process; IMP:MGI.::GO:0009755; P:hormone-mediated signaling pathway; IDA:MGI.::GO:0048609; P:multicellular organismal reproductive process; IMP:MGI.::GO:0051463; P:negative regulation of cortisol secretion; IMP:MGI.::GO:0060125; P:negative regulation of growth hormone secretion; IMP:MGI.::GO:0046676; P:negative regulation of insulin secretion; IMP:MGI.::GO:0048011; P:nerve growth factor receptor signaling pathway; IMP:MGI.::GO:0035265; P:organ growth; IMP:MGI.::GO:0046887; P:positive regulation of hormone secretion; IMP:MGI.::GO:0009967; P:positive regulation of signal transduction; IMP:MGI.::GO:0033628; P:regulation of cell adhesion mediated by integrin; ISS:UniProtKB.::GO:0040014; P:regulation of multicellular organism growth; IMP:MGI.::GO:0046825; P:regulation of protein export from nucleus; IMP:MGI.::GO:0006641; P:triglyceride metabolic process; IMP:MGI.
109P35831    775   PTN12_MOUSE Tyrosine-protein phosphatase non-...2814e-22     101     29     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:MGI.::GO:0002102; C:podosome; IDA:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
110P80560    1001   PTPR2_MOUSE Receptor-type tyrosine-protein ph...2946e-22     100     29     47GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030141; C:secretory granule; IDA:MGI.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
111Q05209    780   PTN12_HUMAN Tyrosine-protein phosphatase non-...2819e-22     100     28     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
112Q61152    453   PTN18_MOUSE Tyrosine-protein phosphatase non-...2952e-21     97.8     27     42GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.
113Q6YI48    1434   PTPRU_CHICK Receptor-type tyrosine-protein ph...2940.0000000008     63.9     24     42GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
114Q99952    460   PTN18_HUMAN Tyrosine-protein phosphatase non-...2808e-21     96.3     27     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.
115P28191    1026   PTP1_CAEEL Tyrosine-protein phosphatase 1 OS=...2721e-20     97.1     30     42GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
116Q64612    1711   PTPRV_RAT Receptor-type tyrosine-protein phos...2842e-20     97.1     29     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0046849; P:bone remodeling; IEP:RGD.
117Q24708    764   CSW_DROVI Tyrosine-protein phosphatase corksc...2451e-19     93.6     30     45GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0007362; P:terminal region determination; ISS:UniProtKB.::GO:0008293; P:torso signaling pathway; ISS:UniProtKB.
118Q92729    1446   PTPRU_HUMAN Receptor-type tyrosine-protein ph...2940.000000002     62.8     24     39GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; NAS:UniProtKB.
119P29349    845   CSW_DROME Tyrosine-protein phosphatase corksc...440.04     39.7     41     66GO:0005737; C:cytoplasm; NAS:UniProtKB.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:FlyBase.::GO:0004728; F:receptor signaling protein tyrosine phosphatase activity; NAS:FlyBase.
GO:0008069; P:dorsal/ventral axis specification, ovarian follicular epithelium; IMP:FlyBase.::GO:0007173; P:epidermal growth factor receptor signaling pathway; IMP:FlyBase.::GO:0007427; P:epithelial cell migration, open tracheal system; IMP:FlyBase.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; IMP:FlyBase.::GO:0007444; P:imaginal disc development; IMP:FlyBase.::GO:0007498; P:mesoderm development; IMP:FlyBase.::GO:0000278; P:mitotic cell cycle; IMP:FlyBase.::GO:0007428; P:primary branching, open tracheal system; TAS:FlyBase.::GO:0045314; P:regulation of compound eye photoreceptor development; IMP:FlyBase.::GO:0045500; P:sevenless signaling pathway; TAS:FlyBase.::GO:0007362; P:terminal region determination; IMP:UniProtKB.::GO:0008293; P:torso signaling pathway; IGI:UniProtKB.::GO:0007418; P:ventral midline development; IMP:FlyBase.
120Q8ISC9    555   CSW_DROSI Tyrosine-protein phosphatase corksc...2498e-19     90.5     29     45GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0007362; P:terminal region determination; ISS:UniProtKB.::GO:0008293; P:torso signaling pathway; ISS:UniProtKB.
121Q5I145    320   PTPH3_MDBVW Tyrosine phosphatase H3 OS=Microp...3211e-18     87.8     24     41
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0030683; P:evasion by virus of host immune response; IEA:UniProtKB-KW.
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